Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Hanwei Cao"'
Autor:
Liyuan Mao, Yan-yan Zhan, Bin Wu, Qiang Yu, Liang Xu, Xiaoting Hong, Linhai Zhong, Panying Mi, Li Xiao, Xinquan Wang, Hanwei Cao, Wenqing Zhang, Binbin Chen, Jingzhou Xiang, Kunrong Mei, Ravi Radhakrishnan, Wei Guo, Tianhui Hu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Elevated expression of ULK1 is known to be inversely correlated with breast cancer metastasis. Here, the authors report Exo70 as a substrate of ULK1 that suppresses cancer metastasis, and show that ERK1/2 mediated phosphorylation of Exo70 leads to op
Externí odkaz:
https://doaj.org/article/7a8d91e583c5427ba8f9a268e2cf0b5b
Autor:
Dandan Li, Li Xiao, Yuetan Ge, Yu Fu, Wenqing Zhang, Hanwei Cao, Binbin Chen, Haibin Wang, Yan-yan Zhan, Tianhui Hu
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-6 (2018)
Abstract Tob1, a Tob/BTG anti-proliferative protein family member, functions as a tumour suppressor in many cancers. Here, we reveal a unique oncogenic role of Tob1 in colon cancer. Tob1 expression was upregulated during colon cancer progression, was
Externí odkaz:
https://doaj.org/article/7d1a53b12c5045cc8502e2f6b9662a61
Autor:
Xiaoting Hong, Linhai Zhong, Yurou Xie, Kaifeng Zheng, Jinglong Pang, Yesen Li, Yifan Yang, Xiaolin Xu, Panying Mi, Hanwei Cao, Wenqing Zhang, Tianhui Hu, Gang Song, Daxuan Wang, Yan-yan Zhan
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
The Warburg effect is a peculiar feature of cancer’s metabolism, which is an attractive therapeutic target that could aim tumor cells while sparing normal tissue. Matrine is an alkaloid extracted from the herb root of a traditional Chinese medicine
Externí odkaz:
https://doaj.org/article/ece995cda1a645419194407b80d39d78
Autor:
Hasan Ejaz, Nancy Wang, Jonathan J. Wilksch, Andrew J. Page, Hanwei Cao, Shruti Gujaran, Jacqueline A. Keane, Trevor Lithgow, Ikram ul-Haq, Gordon Dougan, Richard A. Strugnell, Eva Heinz
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 11, Pp 1872-1875 (2017)
Klebsiella pneumoniae shows increasing emergence of multidrug-resistant lineages, including strains resistant to all available antimicrobial drugs. We conducted whole-genome sequencing of 178 highly drug-resistant isolates from a tertiary hospital in
Externí odkaz:
https://doaj.org/article/d759a0888f15462d9918e1a903a62f48
Autor:
Yujie Zhao, Xiaoting Hong, Xiong Chen, Chun Hu, Weihong Lu, Baoying Xie, Linhai Zhong, Wenqing Zhang, Hanwei Cao, Binbin Chen, Qian Liu, Yanyan Zhan, Li Xiao, Tianhui Hu
Publikováno v:
Cancers, Vol 13, Iss 14, p 3467 (2021)
Whilst researches elucidating a diversity of intracellular mechanisms, platinum-resistant epithelial ovarian cancer (EOC) remains a major challenge in the treatment of ovarian cancer. Here we report that Exo70, a key subunit of the exocyst complex, c
Externí odkaz:
https://doaj.org/article/ccd3f92dd7144a36b3733934e4da2463
Autor:
Li Xiao, Kaifeng Zheng, Xia Lv, Jihuan Hou, Liang Xu, Yujie Zhao, Fei Song, Yaqiong Fan, Hanwei Cao, Wenqing Zhang, Xiaoting Hong, Yan-yan Zhan, Tianhui Hu
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Exo70, a key component of the Exocyst complex, plays important roles in human cancer progression beyond exocytosis. However, the expression of Exo70 and its prognostic value for patients with colon cancer has not been well investigated to da
Externí odkaz:
https://doaj.org/article/6da550d0c62d4b198d039f062b907a59
Autor:
Lihong Wang, Liping Liu, Yan Shi, Hanwei Cao, Rupesh Chaturvedi, M Wade Calcutt, Tianhui Hu, Xiubao Ren, Keith T Wilson, D Brent Polk, Fang Yan
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36418 (2012)
Berberine, an isoquinoline alkaloid derived from plants, is a traditional medicine for treating bacterial diarrhea and intestinal parasite infections. Although berberine has recently been shown to suppress growth of several tumor cell lines, informat
Externí odkaz:
https://doaj.org/article/a440c293e88a40539fa74725efb7eb4c
Autor:
Jonathan J Wilksch, Ji Yang, Abigail Clements, Jacinta L Gabbe, Kirsty R Short, Hanwei Cao, Rosalia Cavaliere, Catherine E James, Cynthia B Whitchurch, Mark A Schembri, Mary L C Chuah, Zhao-Xun Liang, Odilia L Wijburg, Adam W Jenney, Trevor Lithgow, Richard A Strugnell
Publikováno v:
PLoS Pathogens, Vol 7, Iss 8, p e1002204 (2011)
Klebsiella pneumoniae causes significant morbidity and mortality worldwide, particularly amongst hospitalized individuals. The principle mechanism for pathogenesis in hospital environments involves the formation of biofilms, primarily on implanted me
Externí odkaz:
https://doaj.org/article/1b9418132280410ca0559776e41d2207
Autor:
Yuan Li, Hanwei Cao, Tingting Dong, Xiaoke Wang, Liang Ma, Kun Li, Huiqiang Lou, Chun‐Peng Song, Dongtao Ren
Publikováno v:
Journal of Integrative Plant Biology.
Autor:
Jinying Shen, Yujie Zhao, Linhai Zhong, Tianhui Hu, Xiong Chen, Xiaolin Xu, Daxuan Wang, Yan-yan Zhan, Xiaoting Hong, Hanwei Cao, Yitong Zhou, Jianben Wu, Ying Lin, Wenqing Zhang, Jihuan Hou
Publikováno v:
Cancer Research. 81:5904-5918
Invasive mucinous lung adenocarcinoma (IMA) is a subtype of lung adenocarcinoma with a strong invasive ability. IMA frequently carries "undruggable" KRAS mutations, highlighting the need for new molecular targets and therapies. Nuclear receptor HNF4