Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hanumanth Rao, Pantangi"'
Autor:
Ramakrishna Nirogi, Ilayaraja Kalaikadhiban, Lakshmi Prasanna Rayapati, Hanumanth Rao Pantangi, Prathyusha Chunduru, Satish Jetta, Avinash Jubre, Abdul Rasheed Mohammed
Publikováno v:
Journal of Chromatography Open, Vol 3, Iss , Pp 100073- (2023)
SUVN-911 (Ropanicant) is a novel alpha-4 beta-2 nicotinic acetylcholine receptor (α4β2 nAChR) antagonist being developed for the treatment of major depressive disorders (MDD). An Ultra high-performance liquid chromatography-tandem mass spectrometry
Externí odkaz:
https://doaj.org/article/ea9e09b796bd4eacb6f7dfaae3a236aa
Autor:
Ramakrishna, Nirogi, Ilayaraja, Kalaikadhiban, Naga Surya Prakash, Padala, Hanumanth Rao, Pantangi, Prathyusha, Chunduru, Abdul Rasheed, Mohammed
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 211
Liquid chromatography and the tandem mass spectrometry method to quantitate SUVN-D4010 (Usmarapride) in human plasma and urine have been developed and fully validated in compliance with regulatory guidelines. The sample preparation technique is simpl
Autor:
Rajesh Kumar Boggavarapu, Abdul Rasheed Mohammed, Devender Reddy Ajjala, Ramakrishna Nirogi, Jagadeesh Babu Thentu, Naga Surya Prakash Padala, Hanumanth Rao Pantangi
Publikováno v:
Bioanalysis. 11:971-986
Aim: To evaluate suitability of the LC–MS/MS method to quantify 3,4-dihydroxyphenylglycol (DHPG) that is used as a biomarker for monoamine oxidase (MAO) inhibition. Methods: DHPG was extracted using alumina basic cartridges and quantified on a trip
Autor:
Ramakrishna Nirogi, Ilayaraja Kalaikadhiban, Naga Surya Prakash Padala, Hanumanth Rao Pantangi, Prathyusha Chunduru, Abdul Rasheed Mohammed
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 211:114617
Autor:
Nagasurya Prakash Padala, Gopinadh Bhyrapuneni, Prathyusha Chunduru, Jagadeesh Babu Thentu, Hanumanth Rao Pantangi, Ramakrishna Nirogi
Publikováno v:
Neurochemistry International. 145:105006
Monoamine oxidase (MAO) enzymes, type A and B metabolise the amine neurotransmitters of the body. Selective inhibition of either enzyme is an approach for treating neurodegenerative and stress-induced disorders, and inhibition of an enzyme is proport
Autor:
Hanumanth Rao Pantangi, Rajesh Kumar Boggavarapu, Naga Surya Prakash Padala, Lakshmiprasanna Rayapati, Devender Reddy Ajjala, Raghupathi Aleti, Ramakrishna Nirogi
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 145:423-430
A sensitive and rapid LC-MS/MS method was developed and validated for the quantification of SUVN-502 and M1 of SUVN-502, a 5-HT6 receptor antagonist for the treatment of dementia associated with Alzheimer's disease. Following solid-phase extraction,
Autor:
Gopinadh Bhyrapuneni, Himabindu Vurimindi, Hanumanth Rao Pantangi, Mahesh Reddy Jonnala, Devender Reddy Ajjala, Vishwottam Kandikere, Ramakrishna Nirogi, N. R. Muddana
Publikováno v:
Biomedical Chromatography. 27:1431-1437
A simple and sensitive LC-MS/MS method was developed and validated for the quantitation of pitolisant, an H3 receptor antagonist/inverse agonist. Acetonitrile protein precipitation technique was used to prepare rat blood and brain tissue homogenate s
Autor:
Ramakrishna, Nirogi, Devender Reddy, Ajjala, Vishwottam, Kandikere, Hanumanth Rao, Pantangi, Mahesh Reddy, Jonnala, Gopinadh, Bhyrapuneni, Nageswar Rao, Muddana, Himabindu, Vurimindi
Publikováno v:
Biomedical chromatography : BMC. 27(11)
A simple and sensitive LC-MS/MS method was developed and validated for the quantitation of pitolisant, an H3 receptor antagonist/inverse agonist. Acetonitrile protein precipitation technique was used to prepare rat blood and brain tissue homogenate s
Autor:
Surya Rao Srikakolapu, Vishwottam Kandikere, Hanumanth Rao Pantangi, Devender Reddy Ajjala, Himabindu Vurimindi, Raghupathi Aleti, Vijay Benade, Gopinadh Bhyrapuneni, Ramakrishna Nirogi
Publikováno v:
Journal of pharmaceutical and biomedical analysis.
A sensitive LC-MS/MS method was developed and validated for the quantification of almotriptan in rat brain and blood dialysates. Almotriptan is a 5HT1B/1D receptor agonist used for the treatment of migraine pain. Method consists of rapid gradient elu