Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hanuman T. Kale"'
Autor:
Bess P. Rosen, Qing V. Li, Hyein S. Cho, Dingyu Liu, Dapeng Yang, Sarah Graff, Jielin Yan, Renhe Luo, Nipun Verma, Jeyaram R. Damodaran, Hanuman T. Kale, Samuel J. Kaplan, Michael A. Beer, Simone Sidoli, Danwei Huangfu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Pluripotent stem cells have remarkable self-renewal capacity: the ability to proliferate indefinitely while maintaining the pluripotent identity essential for their ability to differentiate into almost any cell type in the body. To investiga
Externí odkaz:
https://doaj.org/article/83f39b20ccbe4f7c9720d5859d8c1675
Publikováno v:
Stem Cell Research, Vol 39, Iss , Pp - (2019)
Caudal-type homeobox 2 (.Cdx2) transcription factor is an essential regulator of differentiation to the intestinal epithelium, somatic mesoderm and trophectoderm function in the mouse. However, the regulation of Cdx2 in these processes is poorly unde
Externí odkaz:
https://doaj.org/article/08319b1287f6438ba9e2d900d661dcd5
Autor:
Debabrata Jana, Priya Singh, Purnima Sailasree, Mansi Srivast, Nithyapriya Kumar, Vijay V Vishnu, Hanuman T Kale, Jyothi Lakshmi, Gunda Srini, Divya Tej Sowpati, P Chandra Shekar
Mouse epiblast and embryonic stem cells (mESCs) are considered to adhere strict lineage restriction and lack the potential to contribute to trophoectoderm (TE). In contrast, here we report the derivation of trophoblast stem cells (ESTS) from the mESC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64293250c4067e3707b68403a5fe24f4
https://doi.org/10.21203/rs.3.rs-2882798/v1
https://doi.org/10.21203/rs.3.rs-2882798/v1
Autor:
Debabrata Jana, Purnima Sailasree, Priya Singh, Mansi Srivastava, Vijay V Vishnu, Hanuman T Kale, Jyothi Lakshmi, Gunda Srinivas, Divya Tej Sowpati, P Chandra Shekar
SUMMARYmESCs and epiblast are considered to follow strict lineage adherence and lack the potential to contribute to trophoectoderm. Here, we report the derivation of trophoblast stem cells (ESTS) from the mESCs. The single-cell transcriptome and mole
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d8d09eafcf96583ffd27b9d08c5d66a
https://doi.org/10.1101/2023.04.19.537518
https://doi.org/10.1101/2023.04.19.537518
Autor:
Debabrata Jana, Priya Singh, Purnima Sailasree, Nithyapriya Kumar, Vijay V Vishnu, Hanuman T Kale, Jyothi Lakshmi, Asha Kumari, Divya Tej Sowpati, P Chandra Shekar
SummaryHuman pluripotent stem cells (hPSCs) can self-organize into a blastocyst-like structure (blastoid) by virtue of their full developmental potential. The pluripotent mouse embryonic stem cells (mESC) are considered to lack this potential and hen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb1ca18d51dc120af26ec7274815ffc1
https://doi.org/10.1101/2023.04.12.536583
https://doi.org/10.1101/2023.04.12.536583
A NANOG-pERK reciprocal regulatory circuit regulates Nanog autoregulation and ERK signaling dynamics
Autor:
Hanuman T Kale, Rajendra Singh Rajpurohit, Debabrata Jana, Vijay V Vishnu, Mansi Srivastava, Preeti R Mourya, Gunda Srinivas, P Chandra Shekar
Publikováno v:
EMBO reports. 23(11)
The self-renewal and differentiation potential of embryonic stem cells (ESCs) is maintained by the regulated expression of core pluripotency factors. Expression levels of the core pluripotency factor Nanog are tightly regulated by a negative feedback
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbeeef3b8f643c168116c7cfb0aec7e1
https://pubmed.ncbi.nlm.nih.gov/36066347
https://pubmed.ncbi.nlm.nih.gov/36066347
Autor:
Umesh Kumar, Digumarthi V S Sudhakar, Nithyapriya Kumar, Hanuman T Kale, Rajan Kumar Jha, Nalini J Gupta, B N Chakravarthy, Mamata Deenadayal, Aarti Deenadayal Tolani, Swasti Raychaudhuri, P Chandra Shekar, Kumarasamy Thangaraj
The recent epidemiological studies suggest that nearly one out of every 7 reproductive age couples face problem to conceive a child after trying for at least one year. Impaired fertility of the male partner is causative in approximately 50% of the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1234587c45add5609cf6a0ccea7e2caa
https://doi.org/10.1101/2022.01.11.475851
https://doi.org/10.1101/2022.01.11.475851
Autor:
Vishnu V Vijay, Debabrata Jana, Hanuman T. Kale, G. Srinivas, P. Chandra Shekar, Rajendra Singh Rajpurohit, Preeti R Mourya, Mansi Srivastava
The self-renewal and differentiation potential of Embryonic stem cells (ESCs) is maintained by the regulated expression of core pluripotency factors. The expression level of core pluripotency factor Nanog is tightly regulated by a negative feedback a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de8ca268ac2c845347fabc286b0f6948
https://doi.org/10.1101/2021.06.28.450121
https://doi.org/10.1101/2021.06.28.450121
Autor:
Shipra Sharma, Sejal Patwardhan, Hanuman T. Kale, Tanusri Roy, Lakshmi Kavitha Sthanam, P. Chandra Shekar, Shamik Sen, Kiran Kondabagil, Pradip V. Shinde, Avi Shukla
Publikováno v:
Biomaterials. 280
Stem cell differentiation is dictated by the dynamic crosstalk between cells and their underlying extracellular matrix. While the importance of matrix degradation mediated by enzymes such as matrix metalloproteinases (MMPs) in the context of cancer i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3291bcc147b60cc3d63ad75990205125
https://pubmed.ncbi.nlm.nih.gov/34871878
https://pubmed.ncbi.nlm.nih.gov/34871878
Publikováno v:
Stem Cell Research, Vol 39, Iss, Pp-(2019)
Caudal-type homeobox 2 (.Cdx2) transcription factor is an essential regulator of differentiation to the intestinal epithelium, somatic mesoderm and trophectoderm function in the mouse. However, the regulation of Cdx2 in these processes is poorly unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c702083eb65a4463b7ce2aa93ab3bb74
http://www.sciencedirect.com/science/article/pii/S1873506119301515
http://www.sciencedirect.com/science/article/pii/S1873506119301515