Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hanuma Kumar Karnati"'
Autor:
David Tweedie, Hanuma Kumar Karnati, Roger Mullins, Chaim G Pick, Barry J Hoffer, Edward J Goetzl, Dimitrios Kapogiannis, Nigel H Greig
Publikováno v:
eLife, Vol 9 (2020)
Traumatic brain injury (TBI) is a serious global health problem, many individuals live with TBI-related neurological dysfunction. A lack of biomarkers of TBI has impeded medication development. To identify new potential biomarkers, we time-dependentl
Externí odkaz:
https://doaj.org/article/a33459bcae204b97993da13e520fc0a6
Autor:
Nigel H. Greig, Barry J. Hoffer, Edward J. Goetzl, Chaim G. Pick, Hanuma Kumar Karnati, David Tweedie, Roger J. Mullins, Dimitrios Kapogiannis
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Traumatic brain injury (TBI) is a serious global health problem, many individuals live with TBI-related neurological dysfunction. A lack of biomarkers of TBI has impeded medication development. To identify new potential biomarkers, we time-dependentl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1999e5d1e86ce8be11321de5dfb3abf7
https://elifesciences.org/articles/55827
https://elifesciences.org/articles/55827
Autor:
Roger J. Mullins, David Tweedie, Hanuma Kumar Karnati, Chaim G. Pick, Barry J. Hoffer, Edward J. Goetzl, Dimitrios Kapogiannis, Nigel H. Greig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62ce1ff08fbf82debdc833f8b46b1d89
https://doi.org/10.7554/elife.55827.sa2
https://doi.org/10.7554/elife.55827.sa2
Autor:
Nigel H. Greig, Balmiki Ray, Peter T. Nelson, Hanuma Kumar Karnati, Kumar Sambamurti, Bryan Maloney, Debomoy K. Lahiri
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-17 (2020)
Translational Psychiatry, Vol 10, Iss 1, Pp 1-17 (2020)
Rivastigmine (or Exelon) is a cholinesterase inhibitor, currently used as a symptomatic treatment for mild-to-moderate Alzheimer’s disease (AD). Amyloid-β peptide (Aβ) generated from its precursor protein (APP) by β-secretase (or BACE1) and γ-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a699e14e783d58ea377ba5d558f35f
http://europepmc.org/articles/PMC7026402
http://europepmc.org/articles/PMC7026402
Autor:
Joseph H. Garcia, David Tweedie, Dimitrios Kapogiannis, Robert E. Becker, Nigel H. Greig, Hanuma Kumar Karnati
Traumatic brain injury (TBI) is a major cause of injury-related death throughout the world and lacks effective treatment. Surviving TBI patients often develop neuropsychiatric symptoms, and the molecular mechanisms underlying the neuronal damage and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d723cbcbbcb708a44f08c0aeccab874
https://europepmc.org/articles/PMC6444902/
https://europepmc.org/articles/PMC6444902/
Autor:
Seema Gulyani, David Tweedie, Maja Mustapić, Yazhou Li, Simon S. Skene, Dimitrios Kapogiannis, Hanuma Kumar Karnati, Sahil Chawla, Dilan Athauda, Kashfia Chowdhury, Nigel H. Greig, Thomas Foltynie
Publikováno v:
JAMA neurology. 76(4)
Importance: Exenatide, a glucagon-like peptide 1 agonist used in type 2 diabetes, was recently found to have beneficial effects on motor function in a randomized, placebo-controlled trial in Parkinson disease (PD). Accumulating evidence suggests that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67720cf13ab8bb60c37e3ad19a7e4496
https://pubmed.ncbi.nlm.nih.gov/30958554
https://pubmed.ncbi.nlm.nih.gov/30958554
Autor:
Jia Yi Wang, Chong Chi Chiu, David Tweedie, Yi En Liao, Ling Yu Yang, Nigel H. Greig, Jing Ya Wang, Hanuma Kumar Karnati
Publikováno v:
Journal of Neuroscience Methods. 272:38-49
Traumatic brain injury (TBI) is a leading cause of mortality and morbidity worldwide. Neuroinflammation is prominent in the short and long-term consequences of neuronal injuries that occur after TBI. Neuroinflammation involves the activation of glia,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033779ccd8b39a8ad7a72b27e022a3b3
https://doi.org/10.1016/j.jneumeth.2016.06.018
https://doi.org/10.1016/j.jneumeth.2016.06.018
Publikováno v:
Current Pharmaceutical Design. 23
Adipokines are bioactive proteins that mediate proliferation, metabolism, inflammation, and angiogenesis. Adiponectin is an important adipokine that exerts multiple key functions via its anti-metabolic syndrome and anti-inflammatory properties. A num
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3376a45fbe1e7c775c2182e3e14fb178
https://doi.org/10.2174/1381612823666170208123553
https://doi.org/10.2174/1381612823666170208123553
Autor:
Ravi Kumar Gutti, Itishri Sahu, Hanuma Kumar Karnati, Satya Ratan Pasupuleti, Ram Babu Undi, Madhuri Subbiah, Ravinder Kandi, T.R. Kannaki
Publikováno v:
Veterinary Research Communications. 39:73-78
Toll-like receptors (TLRs) that sense the microbial pathogens are important components of host immune system. TLRs play key roles in the innate defence mechanism against pathogens, in the development of adaptive immunity, and are possibly the major d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718308890585f3a3b093add1dc8f2562
https://doi.org/10.1007/s11259-014-9621-2
https://doi.org/10.1007/s11259-014-9621-2
Autor:
Nigel H. Greig, Noor Ahmad Shaik, Manas Kumar Panigrahi, Nagaiah Kapalavayi, S. Appala R. Bagadi, Hanuma Kumar Karnati, Mohammad Amjad Kamal
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 13:1413-1426
Glioblastoma multiforme is the most common form of intracranial malignancy in humans, and is characterized by aggressive tumor growth, tissue invasion and neurodegenerative properties. The present study investigated the expression status of tight jun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22f33a347b13b0e257bb1475f6369650
https://doi.org/10.2174/1871527313666141023121550
https://doi.org/10.2174/1871527313666141023121550