Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hantian Qiu"'
Publikováno v:
Biology Open, Vol 12, Iss 7 (2023)
Externí odkaz:
https://doaj.org/article/9a0fea094add44608357dcef76821448
Autor:
Ruijuan Zhuang, Yuxia Zhou, Ziyan Wang, Yating Cao, Jun Chen, Liju Xu, Yandan Ren, Yige Zheng, Ziheng Wei, Hantian Qiu, Liangcheng Li, Yang Han, Ye Yun, Xin Chen, Wanjin Hong, Tuanlao Wang
Publikováno v:
PLoS Biology, Vol 21, Iss 6, p e3002142 (2023)
Rab26 is known to regulate multiple membrane trafficking events, but its role in insulin secretion in pancreatic β cells remains unclear despite it was first identified in the pancreas. In this study, we generated Rab26-/- mice through CRISPR/Cas9 t
Externí odkaz:
https://doaj.org/article/50ab4331ce804b418c14a1d14646b0f4
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Cilia play crucial roles in sensing and transducing extracellular signals. Bidirectional protein trafficking within cilia is mediated by the intraflagellar transport (IFT) machinery containing IFT-A and IFT-B complexes, with the aid of kines
Externí odkaz:
https://doaj.org/article/1a32ca68ec684dd1852dae7dc93a57e0
Autor:
Huiying Liu, Yuxia Zhou, Hantian Qiu, Ruijuan Zhuang, Yang Han, Xiaoqing Liu, Xi Qiu, Ziyan Wang, Liju Xu, Ran Tan, Wanjin Hong, Tuanlao Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Abstract Rab proteins play crucial roles in membrane trafficking. Some Rab proteins are implicated in cancer development through regulating protein sorting or degradation. In this study, we found that the expression of Rab26 is suppressed in the aggr
Externí odkaz:
https://doaj.org/article/cf4f7a82476c496c8fb862fe1bdfa146
Publikováno v:
Biology Open, Vol 10, Iss 9 (2021)
INPP5E, a phosphoinositide 5-phosphatase, localizes on the ciliary membrane via its C-terminal prenyl moiety, and maintains the distinct ciliary phosphoinositide composition. The ARL3 GTPase contributes to the ciliary membrane localization of INPP5E
Externí odkaz:
https://doaj.org/article/5dc95fdd7b6d4a12a441bc7369127e03
Publikováno v:
Biology Open, Vol 10, Iss 1 (2021)
Compositions of proteins and lipids within cilia and on the ciliary membrane are maintained to be distinct from those of the cytoplasm and plasma membrane, respectively, by the presence of the ciliary gate. INPP5E is a phosphoinositide 5-phosphatase
Externí odkaz:
https://doaj.org/article/2c7c853c853c4ff7bd173fca789142f6
Autor:
Shunya Hiyamizu, Hantian Qiu, Laura Vuolo, Nicola L. Stevenson, Caroline Shak, Kate J. Heesom, Yuki Hamada, Yuta Tsurumi, Shuhei Chiba, Yohei Katoh, David J. Stephens, Kazuhisa Nakayama
Publikováno v:
Journal of Cell Science. 136
The dynein-2 complex must be transported anterogradely within cilia to then drive retrograde trafficking of the intraflagellar transport (IFT) machinery containing IFT-A and IFT-B complexes. Here, we screened for potential interactions between the dy
Autor:
Zhuang Zhou, Hantian Qiu, Roiner-Francisco Castro-Araya, Ryota Takei, Kazuhisa Nakayama, Yohei Katoh
Publikováno v:
Human Molecular Genetics. 31:1681-1693
The IFT-B complex mediates ciliary anterograde protein trafficking and membrane protein export together with the BBSome. Bardet-Biedl syndrome (BBS) is caused by mutations in not only all BBSome subunits but also in some IFT-B subunits, including IFT
Autor:
Ruijuan Zhuang, Yuxia Zhou, Ziyan Wang, Yating Cao, Liju Xu, Yandan Ren, Yige Zheng, Ziheng Wei, Jun Chen, Hantian Qiu, Liangcheng Li, Yang Han, Ye Yun, Xin Chen, Wanjin Hong, Tuanlao Wang
Rab26 is known to regulate multiple membrane trafficking events, but its role in insulin secretion of pancreatic β-cells remains unclear despite it was first identified in the pancreas. In this study, we generated Rab26−/− mice through CRISPR/Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::738656afd35f2ea67367a073c0f929b5
https://doi.org/10.21203/rs.3.rs-1726613/v1
https://doi.org/10.21203/rs.3.rs-1726613/v1
Autor:
Yuxia Zhou, Yang Han, Xiaoqing Liu, Ran Tan, Huiying Liu, Ziyan Wang, Wanjin Hong, Liju Xu, Xi Qiu, Ruijuan Zhuang, Hantian Qiu, Tuanlao Wang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Cell Death & Disease
Cell Death & Disease
Rab proteins play crucial roles in membrane trafficking. Some Rab proteins are implicated in cancer development through regulating protein sorting or degradation. In this study, we found that the expression of Rab26 is suppressed in the aggressive br