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Specific communication between gene promoters and enhancers is critical for accurate regulation of gene expression. However, it remains unclear how specific interactions between multiple regulatory elements and genes contained within a single chromat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9699e5c0b6a2e4aa03d0f6e7bc061dbe
Autor:
King AJ; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Songdej D; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Division of Hematology/Oncology, Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand., Downes DJ; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Beagrie RA; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Liu S; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; Chinese Academy of Medical Sciences Oxford Institute, University of Oxford, Oxford, UK., Buckley M; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Hua P; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Suciu MC; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Marieke Oudelaar A; Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Hanssen LLP; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Jeziorska D; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Roberts N; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Carpenter SJ; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Francis H; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Telenius J; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Olijnik AA; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Sharpe JA; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Sloane-Stanley J; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Eglinton J; National Haemoglobinopathy Reference Laboratory, Department of Haematology, Level 4, John Radcliffe Hospital, Oxford, UK., Kassouf MT; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Orkin SH; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School and Howard Hughes Medical Institute, Boston, MA, USA., Pennacchio LA; Functional Genomics Department, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.; Comparative Biochemistry Program, University of California, Berkeley, CA, USA., Davies JOJ; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK., Hughes JR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Higgs DR; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. doug.higgs@imm.ox.ac.uk., Babbs C; MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. christian.babbs@imm.ox.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2021 Jul 21; Vol. 12 (1), pp. 4439. Date of Electronic Publication: 2021 Jul 21.
Autor:
Hua P; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Badat M; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hanssen LLP; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hentges LD; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Crump N; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Downes DJ; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Jeziorska DM; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Oudelaar AM; Max Planck Institute for Biophysical Chemistry, Göttingen, Germany., Schwessinger R; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Taylor S; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Milne TA; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hughes JR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Higgs DR; Laboratory of Gene Regulation, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Davies JOJ; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. james.davies@imm.ox.ac.uk.
Publikováno v:
Nature [Nature] 2021 Jul; Vol. 595 (7865), pp. 125-129. Date of Electronic Publication: 2021 Jun 09.
Autor:
Taylor, Tiegh1 (AUTHOR), Zhu, Hongyu Vicky1 (AUTHOR), Moorthy, Sakthi D.1 (AUTHOR), Khader, Nawrah1 (AUTHOR), Mitchell, Jennifer A.1,2 (AUTHOR) ja.mitchell@utoronto.ca
Publikováno v:
PLoS Genetics. 12/13/2024, Vol. 20 Issue 12, p1-19. 19p.
Autor:
Conneely, Lee J.1,2,3 (AUTHOR), Hurgobin, Bhavna1,2 (AUTHOR), Ng, Sophia1,2 (AUTHOR), Tamiru-Oli, Muluneh1,2 (AUTHOR), Lewsey, Mathew G.1,2,3 (AUTHOR) M.Lewsey@latrobe.edu.au
Publikováno v:
BMC Plant Biology. 11/14/2024, p1-20. 20p.
The 3D Genome in Brain Development: An Exploration of Molecular Mechanisms and Experimental Methods.
Autor:
Rahman, Samir1,2,3,4,5 (AUTHOR) rahman.samir33@gmail.com, Roussos, Panos1,2,3,4,5,6,7 (AUTHOR)
Publikováno v:
Neuroscience Insights. 10/29/2024, p1-15. 15p.
Autor:
Dhillon, Namrita1 (AUTHOR), Kamakaka, Rohinton T.2 (AUTHOR) Rohinton@ucsc.edu
Publikováno v:
Epigenetics & Chromatin. 9/14/2024, Vol. 17 Issue 1, p1-18. 18p.
Autor:
Di Berardino, Chiara1 (AUTHOR) cdiberardino@unite.it, Peserico, Alessia1 (AUTHOR), Camerano Spelta Rapini, Chiara1 (AUTHOR), Liverani, Liliana2,3 (AUTHOR), Capacchietti, Giulia1 (AUTHOR), Russo, Valentina1 (AUTHOR), Berardinelli, Paolo1 (AUTHOR), Unalan, Irem2 (AUTHOR), Damian-Buda, Andrada-Ioana2 (AUTHOR), Boccaccini, Aldo R.2 (AUTHOR), Barboni, Barbara1 (AUTHOR)
Publikováno v:
Reproductive Biology & Endocrinology. 8/2/2024, Vol. 22 Issue 1, p1-19. 19p.
Autor:
Oudelaar AM; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Harrold CL; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hanssen LLP; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Telenius JM; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Higgs DR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hughes JR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. jim.hughes@imm.ox.ac.uk.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. jim.hughes@imm.ox.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2019 Nov 27; Vol. 10 (1), pp. 5412. Date of Electronic Publication: 2019 Nov 27.
Autor:
Oudelaar AM; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Davies JOJ; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hanssen LLP; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Telenius JM; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Schwessinger R; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Liu Y; Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA., Brown JM; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Downes DJ; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Chiariello AM; Dipartimento di Fisica, Università di Napoli Federico II, and INFN Napoli, Complesso di Monte Sant'Angelo, Naples, Italy., Bianco S; Dipartimento di Fisica, Università di Napoli Federico II, and INFN Napoli, Complesso di Monte Sant'Angelo, Naples, Italy., Nicodemi M; Dipartimento di Fisica, Università di Napoli Federico II, and INFN Napoli, Complesso di Monte Sant'Angelo, Naples, Italy., Buckle VJ; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Dekker J; Program in Systems Biology, Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Higgs DR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Hughes JR; MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. jim.hughes@imm.ox.ac.uk.; MRC WIMM Centre for Computational Biology, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK. jim.hughes@imm.ox.ac.uk.
Publikováno v:
Nature genetics [Nat Genet] 2018 Dec; Vol. 50 (12), pp. 1744-1751. Date of Electronic Publication: 2018 Oct 29.