Zobrazeno 1 - 10
of 338
pro vyhledávání: '"Hansruedi, Glatt"'
Autor:
Hansruedi Glatt, Sarah Yasmin Weißenberg, Anke Ehlers, Alfonso Lampen, Albrecht Seidel, Fabian Schumacher, Wolfram Engst, Walter Meinl
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 7, p 3824 (2024)
We previously found that feeding rats with broccoli or cauliflower leads to the formation of characteristic DNA adducts in the liver, intestine and various other tissues. We identified the critical substances in the plants as 1-methoxy-3-indolylmethy
Externí odkaz:
https://doaj.org/article/f8ec43083ae74669a074b02890305dc4
The comparison of cytotoxic and genotoxic activities of glucosinolates, isothiocyanates, and indoles
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Chemopreventive properties of Brassica vegetables are attributed mainly to their characteristic compounds—glucosinolates (GLs) and their main hydrolysis products—isothiocyanates (ITCs) and indoles. In this study, we compared antiprolifer
Externí odkaz:
https://doaj.org/article/3972d092a4934c0caf42361d93ec23d3
Autor:
Yun Li, Zhidan Chen, Joseph D. Paonessa, Walter Meinl, Arup Bhattacharya, Hansruedi Glatt, Paul Vouros, Yuesheng Zhang
Publikováno v:
Cancer Medicine, Vol 7, Iss 11, Pp 5604-5610 (2018)
Abstract Bladder cancer risk is 3‐4 times higher in men than women, but the reason is poorly understood. In mice, male bladder is also more susceptible than female bladder to 4‐aminobiphenyl (ABP), a major human bladder carcinogen; however, femal
Externí odkaz:
https://doaj.org/article/0bd0fa53678549dd93c5657143a196ac
Autor:
Yujian Wang, Zongying Yang, Hansruedi Glatt, Keqi Hu, Yungang Liu, Hang Yu, Ruifang Fan, Meiqi Song, Albert Braeuning
Publikováno v:
Environmental Science & Technology. 55:10001-10011
Bisphenol (BP) compounds are endocrine-disrupting organic pollutants. BPs may increase the messenger RNA (mRNA) transcripts of nuclear receptors (NRs) regulating the expression of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes. Their impact on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd72e8d243aff78f3a26e7e0152999d
https://doi.org/10.1021/acs.est.1c02189
https://doi.org/10.1021/acs.est.1c02189
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 7, Pp 14996-15016 (2013)
Pak choi plants (Brassica rapa ssp. chinensis) were treated with different signaling molecules methyl jasmonate, jasmonic acid, linolenic acid, and methyl salicylate and were analyzed for specific changes in their glucosinolate profile. Glucosinolate
Externí odkaz:
https://doaj.org/article/4830d4c6917347b5ace458675920f210
Publikováno v:
Archives of Toxicology. 95:703-713
1-Methylpyrene (1-MP) is a common environmental pollutant and animal carcinogen. After sequential activation by cytochromes P450 and sulfotransferases, it induced gene mutations and micronuclei in mammalian cells. The type of micronuclei formed, enti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e04ab43adf256a3104834ce6564df3
https://doi.org/10.1007/s00204-020-02933-w
https://doi.org/10.1007/s00204-020-02933-w
Publikováno v:
Environmental and Molecular Mutagenesis. 61:622-634
Benzene is a human carcinogen that requires metabolic activation. We previously observed that benzene and its hydroxylated metabolites induce micronuclei in mammalian cells expressing human CYP2E1. This study was initially aimed to study another endp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c976a498d77d1b92572a11adacacc95
https://doi.org/10.1002/em.22375
https://doi.org/10.1002/em.22375
Publikováno v:
Archives of toxicology, 96(3):933–944
Juices of Brassica vegetables are mutagenic and form characteristic DNA adducts in bacteria and mammalian cells. In this study, we examined whether such adducts are also formed in vivo in animal models. Rats fed raw broccoli ad libitum in addition to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c059e1627c5dde5f953462bb0733165
https://link.springer.com/article/10.1007/s00204-021-03216-8#Sec18
https://link.springer.com/article/10.1007/s00204-021-03216-8#Sec18
Autor:
Hansruedi Glatt
Publikováno v:
Current Drug Metabolism. 23:1089-1089
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aa24b62a9fb7dedd06155bee372a911
https://doi.org/10.2174/138920022314230214155111
https://doi.org/10.2174/138920022314230214155111
The comparison of cytotoxic and genotoxic activities of glucosinolates, isothiocyanates, and indoles
Publikováno v:
Scientific reports. 12(1)
Chemopreventive properties of Brassica vegetables are attributed mainly to their characteristic compounds—glucosinolates (GLs) and their main hydrolysis products—isothiocyanates (ITCs) and indoles. In this study, we compared antiproliferative act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3887e4b4437f02cfb6f583daaab9be
https://pubmed.ncbi.nlm.nih.gov/35318378
https://pubmed.ncbi.nlm.nih.gov/35318378