Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hanspeter Schawalder"'
Autor:
Florence A. Scholl, Peter Maier, Bashar Saad, Veronika Streit, F. Waechter, Hanspeter Schawalder, Helmut Thomas
Publikováno v:
European Journal of Biochemistry. 213:805-814
The influence of cell-substrata interactions on the preservation of basal or in-vivo-induced microsomal cytochrome P-450 isoenzyme contents in cultured rat hepatocytes and on the adaptive responses after exposure to phenobarbital or 3-methylcholanthr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758f7a5cc8a77ecf80467b0a502da61f
https://doi.org/10.1111/j.1432-1033.1993.tb17823.x
https://doi.org/10.1111/j.1432-1033.1993.tb17823.x
Publikováno v:
European journal of pharmacology. 368(1)
Nonparenchymal cells, particularly Kupffer cells, might play an important role in the modulation of xenobiotic metabolism in liver and its pharmacological and toxicological consequences. This intercellular communication via the exchange of soluble fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2d9fb5198944a9066d09fb500105241
https://pubmed.ncbi.nlm.nih.gov/10096772
https://pubmed.ncbi.nlm.nih.gov/10096772
Publikováno v:
Toxicology and applied pharmacology. 126(2)
The role of oxygen tension, insulin, and glucagon on the preservation and induction of cytochrome P450 isoenzyme activities and contents was investigated in rat hepatocytes cultured for 4 days on crude liver membrane fractions at 4 or 13% O2. At 13%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad26c24983bb1731e0b7623ca9a347ce
https://pubmed.ncbi.nlm.nih.gov/8209390
https://pubmed.ncbi.nlm.nih.gov/8209390
Autor:
Peter Maier, Hanspeter Schawalder
Publikováno v:
Journal of cellular physiology. 156(1)
Freshly isolated rat hepatocytes were cultured at periportal- (13% 0,) or perivenous-like (4% 0,) oxygen tension and exposed to subtoxic exposure levels of cyproterone acetate (CPA: 10-330 pM), phenobarbital (PB: 0.75-6 mM), and dimethylsulfoxide (DM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bfd12025f1d3870211a7551feb4ac83
https://pubmed.ncbi.nlm.nih.gov/8314852
https://pubmed.ncbi.nlm.nih.gov/8314852
Publikováno v:
In vitro cellulardevelopmental biology : journal of the Tissue Culture Association. (1)
Over time, rat hepatocytes cultured on collagen lose the capacity to express liver-specific functions. The influence on this degradation process of an alternative substratum--crude membrane fractions prepared from the liver of the same rat strain--wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af346761cd645d814a99e2d71a73077d
https://pubmed.ncbi.nlm.nih.gov/7680337
https://pubmed.ncbi.nlm.nih.gov/7680337
Publikováno v:
Environmental and Molecular Mutagenesis. 10:275-284
The mutagenic activities of aristolochic acid I (AAI) and II (AAII), the two main components of aristolochic acid (AA), were tested for mutagenicity in vivo in a subcutaneous granulation tissue in rats and in vitro in the corresponding freshly isolat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc008205f85c92a670dc600f842241c
https://doi.org/10.1002/em.2850100306
https://doi.org/10.1002/em.2850100306
Publikováno v:
Mutation research. 143(3)
The mutagenic activity of the natural plant product aristolochic acid (AA) was tested in the Granuloma Pouch Assay, which detects gene mutations induced in a subcutaneous granuloma tissue of rats. After direct exposure of the target tissue, AA induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e60a61a74c9bbfc557f73c97b968344
https://pubmed.ncbi.nlm.nih.gov/4010694
https://pubmed.ncbi.nlm.nih.gov/4010694
Publikováno v:
Toxicology. 25(1)
Cell detachment and cloning efficiency of Baby Hamster Kidney cells (BHK-21 C13) were used as parameters to quantify cytotoxicity in vitro of 3 endogenous chemicals (glutathione, L-methionine, L-cysteine HCl) and 4 organotin compounds (tributyltinoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1736ef525b494f4e3fdc0918df27304
https://pubmed.ncbi.nlm.nih.gov/7157390
https://pubmed.ncbi.nlm.nih.gov/7157390