A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians

Autor: Piaggi, P, Masindova, I, Muller, Yl, Mercader, J, Wiessner, Gb, Chen, P, Sigma Type, 2 Diabetes Consortium, Kobes, S, Hsueh, Wc, Mongalo, M, Knowler, Wc, Krakoff, J, Hanson, Rl, Bogardus, C, Baier, Lj

Publikováno v: Diabetes

Pima Indians living in Arizona have a high prevalence of obesity, and we have previously shown that a relatively lower energy expenditure (EE) predicts weight and fat mass gain in this population. EE is a familial trait (heritability = 0.52); therefo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52245e55e4e99e30945ae3c96d583862
https://doi.org/10.2337/db16-1565

Linkage disequilibrium mapping of the type 2 diabetes susceptibility variants on chromosome Iq in European populations

Autor: Zeggini, E, Rayner, W, Groves, CJ, Hanson, RL, Mitchell, BD, O'Connell, J, Vaxillaire, M, Froguel, P, Hunt, S, Cardon, L, Elbein, SC, Shuldiner, A, Deloukas, P, McCarthy, MI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c2c06168dfda887123e3c93230e133e9
https://ora.ox.ac.uk/objects/uuid:e2ce62f7-cc22-414b-b7ec-d73f3b1c7af7

Selecting SNPs informative for African, American Indian and European Ancestry: Application to the Family Investigation of Nephropathy and Diabetes (FIND)

Autor: Williams, RC, Elston, RC, Kumar, P, Knowler, WC, Abboud, HE, Adler, S, Bowden, DW, Divers, J, Freedman, BI, Igo, RP, Ipp, E, Iyengar, SK, Kimmel, PL, Klag, MJ, Kohn, O, Langefeld, CD, Leehey, DJ, Nelson, RG, Nicholas, SB, Pahl, MV, Parekh, RS, Rotter, JI, Schelling, JR, Sedor, JR, Shah, VO, Smith, MW, Taylor, KD, Thameem, F, Thornley-Brown, D, Winkler, CA, Guo, X, Zager, P, Hanson, RL, FIND Research Group, S.K. Iyengar, Goddard, KAB, Olson, JM, Ialacci, S, Fondran, J, Horvath, A, Igo, R, Jun, G, Kramp, K, Molineros, J, Quade, SRE, Schelling, J, Pickens, A, Humbert, L, Getz-Fradley, L, Pahl, M, Seldin, MF, Snyder, S, Tayek, J, Hernandez, E, LaPage, J, Garcia, C, Gonzalez, J, Aguilar, M, Klag, M, Parekh, R, Kao, L, Meoni, L, Whitehead, T, Chester, J, Wolford, J, Jones, L, Juan, R, Lovelace, R, Luethe, C, Phillips, LM, Sewemaenewa, J, Sili, I, Waseta, B, Saad, MF, Chen, YDI, Rotter, J, Taylor, K, Budgett, M, Hariri, F, Shah, V, Scavini, M, Bobelu, A, Abboud, H, Arar, N, Duggirala, R, Kasinath, BS, Stern, M

Publikováno v: Williams, RC; Elston, RC; Kumar, P; Knowler, WC; Abboud, HE; Adler, S; et al.(2016). Selecting SNPs informative for African, American Indian and European Ancestry: Application to the Family Investigation of Nephropathy and Diabetes (FIND). BMC Genomics, 17(1), 325. doi: 10.1186/s12864-016-2654-x. UCLA: Retrieved from: http://www.escholarship.org/uc/item/75f580zv

© 2016 Williams et al. Background: The presence of population structure in a sample may confound the search for important genetic loci associated with disease. Our four samples in the Family Investigation of Nephropathy and Diabetes (FIND), European

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::91cf6123a411ce24ad4e490acd6aadeb
http://www.escholarship.org/uc/item/75f580zv

Identification of a New Signal for Type 2 Diabetes in the Previously Established GLIS3 Gene

Autor: Muller, Y, Hanson, Rl, Piaggi, P, Wiessner, G, Okani, C, Kobes, S, Knowler, Wc, Bogar-Dus, C, Baier, Lj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3728::cec9ab5fe79ef455730388b3451d6e49
http://hdl.handle.net/11568/925378

Identification of Novel Autoantibodies Including Anti-PPARG among Individuals with Type 2 Diabetes

Autor: Chang, Dc, Piaggi, P, Hanson, Rl, Knowler, Wc, Bucci, J, Thio, G, Hohenadel, Mg, Bogardus, C, Krakoff, J

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3728::879a79ee09535d4b79dce15909bad1aa
http://hdl.handle.net/11568/925436