Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hansjoerg Schild"'
Autor:
Bernd Heinrich, Markus Moehler, Manfred P. Lutz, Maria Alsina Maqueda, Catherine Julié, Daniela Aust, Niels Halama, Murielle Mauer, Heike I. Grabsch, Michel Ducreux, Carl C. Schimanski, Florian Lordick, Katrin Goepfert, Hansjoerg Schild, Maike Delic, Anna-Dorothea Wagner, Arnaud Roth
Publikováno v:
European Journal of Cancer, 59, 160-170. ELSEVIER SCI LTD
The new therapeutic approach of using immune checkpoint inhibitors as anticancer agents is a landmark innovation. Early studies suggest that immune checkpoint inhibition might also be effective in patients with gastrointestinal cancer. To improve the
Autor:
Dennis Vogel, Sabine Muth, Jochem Koenig, Danielle Arnold-Schild, Vanessa Popp, Jacques Pouysségur, Natascha Luther, Jennifer Hahlbrock, Steffen Rapp, Hans Christian Probst, Magdalena Huber, Pamela Aranda Lopez, Marina Kreutz, Kathrin Renner, Esther von Stebut, Toszka Bohn, Christina Lueckel, Shogo Endo, Stefanie Pektor, Tobias Bopp, Till-Julius Bruehl, Matthias Klein, Christian Becker, Hansjoerg Schild, Katharina Gerlach, Nobuhiko Kojima, Almut Brand, Benno Weigmann, Edgar Schmitt
Publikováno v:
Nature immunology. 19(12)
Many tumors evolve sophisticated strategies to evade the immune system, and these represent major obstacles for efficient antitumor immune responses. Here we explored a molecular mechanism of metabolic communication deployed by highly glycolytic tumo
Autor:
Stefan Tenzer, Elmar Jaenicke, Beatrice Mindykowski, Heinz Decker, Hansjoerg Schild, Thorsten Schweikardt, Sebahattin Cirak
Publikováno v:
Developmental & Comparative Immunology. 34:722-733
Allergens from cockroaches cause major asthma-related health problems worldwide. Among them Per a 3 belongs to the most potent allergens. Although the sequences of some members of the Per a 3-family are known, their biochemical and biophysical proper
Autor:
Holger Hebart, Markus P. Radsak, Andreas Michan, Hansjoerg Schild, Hermann Einsele, Juergen Loeffler, Ziad Haddad, Jean-Paul Latgé, Sibylla Braedel, Ulrich Grigoleit
Publikováno v:
British Journal of Haematology. 125:392-399
Summary Invasive aspergillosis (IA) is a leading cause of mortality in haematological patients. Appropriate activation of the innate immune system is crucial for the successful clearance of IA. Therefore, we studied the Aspergillus fumigatus-mediated
Autor:
Matthias Bros, Katharina Plein, Markus P. Radsak, Hansjoerg Schild, Daniel Teschner, Matthias Theobald, Christian Michel, Steve Pruefer, Eva Wagner
Publikováno v:
Blood. 128:3679-3679
Background and Aims: Immunosuppressive medication e.g. by calcineurin inhibitors substantially contributes to the risk for opportunistic fungal infections in patients after allogeneic transplantation (HSCT). It is well known that the nuclear factor o
Autor:
Hansjoerg Schild, Steve Pruefer, Markus P. Radsak, Christian Michel, Daniel Teschner, Matthias Theobald
Publikováno v:
Web of Science
Background and Aims: Immunodeficient patients after allogeneic stem cell transplantation (HSCT) are heavily threatened by opportunistic fungal infections like invasive pulmonary aspergillosis (IPA), partly due to immunosuppressive medication e.g. by
Autor:
Hansjoerg Schild, Mark Denny, Tanja Peters, Markus P. Radsak, Stefan Stevanovic, Peter Langguth, Stefan Tenzer, Karsten Gogoll, Matthias Theobald, Pamela Stein
Publikováno v:
Blood. 126:2224-2224
Introduction: Transcutaneous immunization (TCI) is a novel vaccination strategy to induce strong therapeutic cytotoxic T-lymphocyte (CTL) responses by directly targeting skin-resident professional antigen-presenting cells (APC). This vaccination appr
Autor:
Graham Pawelec, Peter van Endert, Christiane Kellert, Nadja Akkad, Hansjoerg Schild, Barbara Seliger, Stefan Tenzer, Tarish Abbas, Esther Kamphausen
Publikováno v:
Cancer immunology, immunotherapy : CII. 59(8)
Immune surveillance of tumour cells by CD8(+) cytotoxic T cells plays a key role in the establishment and control of an anti-tumour response. This process requires the generation of antigenic peptides, which are largely produced by the proteasome in
Autor:
Gerd Rechtsteiner, Markus P. Radsak, Hans-Georg Rammensee, Helmut Jonuleit, Christopher V. Nicchitta, Deanna M. Carrick, Tobias Warger, Hansjoerg Schild, Philipp Haselmayer, Philipp von Landenberg, Norbert Hilf
Publikováno v:
The Journal of biological chemistry. 281(32)
Activation of dendritic cells by ligands for Toll-like receptors (TLR) is a crucial event in the initiation of innate and adaptive immune responses. Several classes of TLR ligands have been identified that interact with distinct members of the TLR-fa