Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Hansjürgen Agostini"'
Autor:
Stefaniya K. Boneva, Julian Wolf, Malte Jung, Gabriele Prinz, Toco Y. P. Chui, Jacqueline Jauch, Anne Drougard, J. Andrew Pospisilik, Anja Schlecht, Felicitas Bucher, Richard B. Rosen, Hansjürgen Agostini, Günther Schlunck, Clemens A. K. Lange
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Background Despite great advances in proliferative diabetic retinopathy (PDR) therapy over the last decades, one third of treated patients continue to lose vision. While resident vitreous macrophages called hyalocytes have been implicated in
Externí odkaz:
https://doaj.org/article/827468ebd85945bda91aa82c724d8c7e
Autor:
Paula Liang, Jan Ness, Julian Rapp, Stefaniya Boneva, Melanie Schwämmle, Malte Jung, Günther Schlunck, Hansjürgen Agostini, Felicitas Bucher
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Background The IL-6 cytokine family, with its crucial and pleiotropic intracellular signaling pathway STAT3, is a promising target for treating vasoproliferative retinal diseases. Previous research has shown that IL-6 cis-signaling (via memb
Externí odkaz:
https://doaj.org/article/7cb48b4b0707425787674009e469b030
Autor:
Hinrich J. Hufnagel, Claas Lahmann, Hansjürgen Agostini, Clemens Lange, Laurenz J. B. Pauleikhoff, on behalf of the Retina.net CCS study group
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background Central serous chorioretinopathy (CSC) has frequently been associated with increased stress levels as well as an increased prevalence of other psychiatric conditions. This study used standardized psychometric scores to assess stre
Externí odkaz:
https://doaj.org/article/af77bf2425df43bc824eb037ffe39858
Autor:
Focke Ziemssen, Hansjürgen Agostini, Nicolas Feltgen, Robert P. Finger, Christos Haritoglou, Hans Hoerauf, Matthias Iwersen, Martina Porstner, Andreas Clemens, Benjamin Gmeiner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Neovascular age-related macular degeneration (nAMD) is a progressive retinal disease that often leads to severe and permanent vision loss. Early initiation of anti-vascular endothelial growth factor (anti-VEGF) therapy has been shown to pres
Externí odkaz:
https://doaj.org/article/bbd635caba394520bf94b6167c71da92
Autor:
Peipei Zhang, Anja Schlecht, Julian Wolf, Stefaniya Boneva, Yannik Laich, Jana Koch, Franziska Ludwig, Myriam Boeck, Adrian Thien, Carmen Härdtner, Katrin Kierdorf, Hansjürgen Agostini, Günther Schlunck, Marco Prinz, Ingo Hilgendorf, Peter Wieghofer, Clemens Lange
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-18 (2021)
Abstract Background Microglia cells represent the resident innate immune cells of the retina and are important for retinal development and tissue homeostasis. However, dysfunctional microglia can have a negative impact on the structural and functiona
Externí odkaz:
https://doaj.org/article/f0b2242fbf2d4c6787d1cd668f61b8e7
Autor:
Anja Schlecht, Stefaniya Boneva, Henrike Salie, Saskia Killmer, Julian Wolf, Rozina Ida Hajdu, Claudia Auw-Haedrich, Hansjürgen Agostini, Thomas Reinhard, Günther Schlunck, Bertram Bengsch, Clemens AK Lange
Publikováno v:
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Imaging mass cytometry (IMC) combines the principles of flow cytometry and mass spectrometry (MS) with laser scanning spatial resolution and offers unique advantages for the analysis of tissue samples in unprecedented detail. In c
Externí odkaz:
https://doaj.org/article/73d3a0361d9c42be97daa3a33524a5ea
Autor:
Thomas Wecker, Bastian Grundel, Milena Grundel, Marie-Christine Bründer, Simon Trick, Clemens Lange, Daniel Böhringer, Hansjürgen Agostini, Andreas Stahl
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Macular edema (ME) is the most frequent vision threatening consequence after retinal vein occlusion (RVO). In this study, we evaluate the effect of dexamethasone intravitreal implants (DII, Ozurdex) in a real-life cohort of 99 patients with
Externí odkaz:
https://doaj.org/article/a618870fd8174289bae2b33e07f100e2
Autor:
Julian Wolf, Stefaniya Boneva, Dennis-Dominik Rosmus, Hansjürgen Agostini, Günther Schlunck, Peter Wieghofer, Anja Schlecht, Clemens Lange
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Microglia are the tissue-resident macrophages of the retina and brain, being critically involved in organ development, tissue homeostasis, and response to cellular damage. Until now, little is known about the molecular signature of human retinal micr
Externí odkaz:
https://doaj.org/article/099f2dc871014833af472a271940d16a
Autor:
Julian Wolf, Rozina Ida Hajdu, Stefaniya Boneva, Anja Schlecht, Thabo Lapp, Katrin Wacker, Hansjürgen Agostini, Thomas Reinhard, Claudia Auw-Hädrich, Günther Schlunck, Clemens Lange
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
With a worldwide prevalence of ~12%, pterygium is a common degenerative and environmentally triggered ocular surface disorder characterized by wing-shaped growth of conjunctival tissue onto the cornea that can lead to blindness if left untreated. Thi
Externí odkaz:
https://doaj.org/article/907a6eef25cd4843b9014c4ee31c215d
Autor:
Stefaniya Konstantinova Boneva, Julian Wolf, Rozina Ida Hajdú, Gabriele Prinz, Henrike Salié, Anja Schlecht, Saskia Killmer, Yannik Laich, Henrik Faatz, Albrecht Lommatzsch, Martin Busch, Felicitas Bucher, Andreas Stahl, Daniel Böhringer, Bertram Bengsch, Günther Schlunck, Hansjürgen Agostini, Clemens A. K. Lange
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundRetinal neovascularization (RNV) membranes can lead to a tractional retinal detachment, the primary reason for severe vision loss in end-stage disease proliferative diabetic retinopathy (PDR). The aim of this study was to characterize the m
Externí odkaz:
https://doaj.org/article/f02067e509894f23bc36ee86663e2653