Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Hansjörg Eibl"'
Autor:
Doaa M. Ali, Himanshu Soni, Hansjörg Eibl, Björn Tews, Martin R. Berger, Ashwini Kumar Sharma, Rainer König, Shariq S. Ansari
Publikováno v:
Cell Death and Disease, Vol 9, Iss 3, Pp 1-15 (2018)
Cell Death & Disease
Cell Death & Disease
Endoplasmic reticulum (ER) plays an essential role in cell function and survival. Accumulation of unfolded or misfolded proteins in the lumen of the ER activates the unfolded protein response (UPR), resulting in ER stress and subsequent apoptosis. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b304c43cc7d724ea644c5b45cdbed14
http://link.springer.com/article/10.1038/s41419-018-0342-2
http://link.springer.com/article/10.1038/s41419-018-0342-2
Autor:
Hansjörg Eibl, Clemens Unger
Publikováno v:
Lipids. 22(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a625b683b0f1cb7c9b57525fb26af69
https://pubmed.ncbi.nlm.nih.gov/27519639
https://pubmed.ncbi.nlm.nih.gov/27519639
Autor:
Bernhard Erdlenbruch, Dagmar E H Heinemann, Anja Jünemann, Wilfried Kugler, T. Hansjörg Eibl, Max Lakomek
Publikováno v:
Journal of Neurochemistry. 82:1160-1170
Erucylphosphocholine (ErPC) is a promising anti-neoplastic drug for the treatment of malignant brain tumours. It exerts strong anti-cancer activity in vivo and in vitro and induces apoptosis even in chemoresistant glioma cell lines. The purpose of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9b2de428b79fe7ca4675542f125798c
https://doi.org/10.1046/j.1471-4159.2002.01034.x
https://doi.org/10.1046/j.1471-4159.2002.01034.x
Autor:
Wilfried Kugler, David S. Miller, Gert Fricker, Bernhard Erdlenbruch, Hansjörg Eibl, Mehrnaz Alipour, Max Lakomek
Publikováno v:
British Journal of Pharmacology. 140:1201-1210
1. The blood-brain barrier (BBB) represents the major impediment to successful delivery of therapeutic agents to target tissue within the central nervous system. Intracarotid alkylglycerols have been shown to increase the transfer of chemotherapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4bcd7046d6a2fd5052deb98b6dceaef3
https://doi.org/10.1038/sj.bjp.0705554
https://doi.org/10.1038/sj.bjp.0705554
Publikováno v:
Annals of the New York Academy of Sciences. 1010:307-310
At concentrations effecting apoptosis, the alkylphosphocholine ErPC3 induced increased expression of the Rb protein in breast cancer (MCF-7) and leukemia (SKW-3, AR-230) cell lines as well as hypophosphorylation (K-562, CMLT-1, DOHH-2) and fragmentat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d818e6f7c7a35fbd314d7e14280ae95
https://doi.org/10.1196/annals.1299.054
https://doi.org/10.1196/annals.1299.054
Autor:
Dagmar E H Heinemann, Bernhard Erdlenbruch, Claudia Schinkhof, Jochen Herms, Wilfried Kugler, Hansjörg Eibl, Max Lakomek
Publikováno v:
British Journal of Pharmacology. 139:685-694
The intracarotid administration of alkylglycerols has been reported previously by us to be a novel strategy for increased delivery of various chemotherapeutic drugs to the normal brain and brain tumors in rats. Effectiveness and structure–activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58eb9818ab842b57e37a28aff1303420
https://doi.org/10.1038/sj.bjp.0705302
https://doi.org/10.1038/sj.bjp.0705302