Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Hansjörg, Schild"'
Autor:
David Gomez-Zepeda, Danielle Arnold-Schild, Julian Beyrle, Arthur Declercq, Ralf Gabriels, Elena Kumm, Annica Preikschat, Mateusz Krzysztof Łącki, Aurélie Hirschler, Jeewan Babu Rijal, Christine Carapito, Lennart Martens, Ute Distler, Hansjörg Schild, Stefan Tenzer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Human leukocyte antigen (HLA) class I peptide ligands (HLAIps) are key targets for developing vaccines and immunotherapies against infectious pathogens or cancer cells. Identifying HLAIps is challenging due to their high diversity, low abund
Externí odkaz:
https://doaj.org/article/154f3e9e47394f8b9f6d870b4ac45be5
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/7059dddd547944caa62d6a1afe0077df
Autor:
Julian Sohl, Ann-Kathrin Hartmann, Jennifer Hahlbrock, Joschka Bartneck, Michael Stassen, Matthias Klein, Matthias Bros, Stephan Grabbe, Federico Marini, Kevin Woods, Borhane Guezguez, Matthias Mack, Hansjörg Schild, Sabine Muth, Felix Melchior, Hans Christian Probst, Peter Langguth, Markus P. Radsak
Publikováno v:
npj Vaccines, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/f8b0c33b4f3c4a62a0d15ea12f4f381c
Autor:
Joschka Bartneck, Ann-Kathrin Hartmann, Lara Stein, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Federico Marini, Jonas Pielenhofer, Sophie Luise Meiser, Peter Langguth, Matthias Mack, Sabine Muth, Hans-Christian Probst, Hansjörg Schild, Markus Philipp Radsak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tumor development and progression is shaped by the tumor microenvironment (TME), a heterogeneous assembly of infiltrating and resident host cells, their secreted mediators and intercellular matrix. In this context, tumors are infiltrated by various i
Externí odkaz:
https://doaj.org/article/b6b81cbb0f6c4c90b928a7619a5c1a38
Autor:
Ann-Kathrin Hartmann, Joschka Bartneck, Jonas Pielenhofer, Sophie Luise Meiser, Danielle Arnold-Schild, Matthias Klein, Michael Stassen, Hansjörg Schild, Sabine Muth, Hans Christian Probst, Peter Langguth, Stephan Grabbe, Markus P. Radsak
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionTranscutaneous immunization (TCI) is a non-invasive vaccination method promoting strong cellular immune responses, crucial for the immunological rejection of cancer. Previously, we reported on the combined application of the TLR7 agonist
Externí odkaz:
https://doaj.org/article/45104fbc88c34ace9bbdff9da15c6608
Autor:
Julian Sohl, Ann-Kathrin Hartmann, Jennifer Hahlbrock, Joschka Bartneck, Michael Stassen, Matthias Klein, Matthias Bros, Stephan Grabbe, Federico Marini, Kevin Woods, Borhane Guezguez, Matthias Mack, Hansjörg Schild, Sabine Muth, Felix Melchior, Hans Christian Probst, Peter Langguth, Markus P. Radsak
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Transcutaneous immunization (TCI) utilizing the TLR7 agonist imiquimod (IMQ-TCI) induces T cell-driven protective immunity upon application onto intact skin. In our present work, we combine the anti-psoriatic agent dithranol with IMQ-TCI to
Externí odkaz:
https://doaj.org/article/7d6f5fd597ff43259826599506c19bbf
Autor:
Kristina Riegel, Hajime Yurugi, Janine Schlöder, Helmut Jonuleit, Manuel Kaulich, Friederike Kirschner, Danielle Arnold-Schild, Stefan Tenzer, Hansjörg Schild, Krishnaraj Rajalingam
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-14 (2021)
Abstract Tumors exhibit a variety of strategies to dampen antitumor immune responses. With an aim to identify factors that are secreted from tumor cells, we performed an unbiased mass spectrometry-based secretome analysis in lung cancer cells. Interl
Externí odkaz:
https://doaj.org/article/98255791638d4d7f9a6010011fe837a6
Autor:
Jonas Pielenhofer, Sophie Luise Meiser, Karsten Gogoll, Anna-Maria Ciciliani, Mark Denny, Michael Klak, Berenice M. Lang, Petra Staubach, Stephan Grabbe, Hansjörg Schild, Markus P. Radsak, Hilde Spahn-Langguth, Peter Langguth
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 514 (2023)
The present article exemplifies the application of the concept of quality by design (QbD) for the systematic development of a nanoparticulate imiquimod (IMQ) emulsion gel formulation as an investigational medicinal product (IMP) for evaluation in an
Externí odkaz:
https://doaj.org/article/21953749a5224c1b9daae569bac7ee79
Autor:
Benedikt Jacobs, Veronika Gebel, Lukas Heger, Victoria Grèze, Hansjörg Schild, Diana Dudziak, Evelyn Ullrich
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cellular therapy has entered the daily clinical life with the approval of CAR T cell therapeutics and dendritic cell (DCs) vaccines in the US and the EU. In addition, numerous other adoptive cellular products, including natural killer (NK) cells, are
Externí odkaz:
https://doaj.org/article/17797aafec86438e91508a05b6075534
Autor:
Katarzyna Bogucka, Malvika Pompaiah, Federico Marini, Harald Binder, Gregory Harms, Manuel Kaulich, Matthias Klein, Christian Michel, Markus P Radsak, Sebastian Rosigkeit, Peter Grimminger, Hansjörg Schild, Krishnaraj Rajalingam
Publikováno v:
eLife, Vol 9 (2020)
ERK3 is a ubiquitously expressed member of the atypical mitogen activated protein kinases (MAPKs) and the physiological significance of its short half-life remains unclear. By employing gastrointestinal 3D organoids, we detect that ERK3 protein level
Externí odkaz:
https://doaj.org/article/aa245781e7d048d6adf5fe6eec0917b5