The structural basis of the multi-step allosteric activation of Aurora B kinase.

Autor: Segura-Peña D; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Faculty of Medicine, Oslo, Norway., Hovet O; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Faculty of Medicine, Oslo, Norway.; Department of Biosciences, University of Oslo, Oslo, Norway.; Hylleraas Centre for Quantum Molecular Sciences, University of Oslo, Oslo, Norway., Gogoi H; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Faculty of Medicine, Oslo, Norway., Dawicki-McKenna J; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States., Hansen Wøien SM; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Faculty of Medicine, Oslo, Norway., Carrer M; Hylleraas Centre for Quantum Molecular Sciences, University of Oslo, Oslo, Norway.; Department of Chemistry, University of Oslo, Oslo, Norway., Black BE; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States., Cascella M; Hylleraas Centre for Quantum Molecular Sciences, University of Oslo, Oslo, Norway.; Department of Chemistry, University of Oslo, Oslo, Norway., Sekulic N; Centre for Molecular Medicine Norway (NCMM), Nordic EMBL Partnership, Faculty of Medicine, Oslo, Norway.

Publikováno v: ELife [Elife] 2023 May 25; Vol. 12. Date of Electronic Publication: 2023 May 25.