Psilocybin-induced reduction in chronic cluster headache attack frequency correlates with changes in hypothalamic functional connectivity

Autor: Madsen, M. K., Petersen, A. S., Stenbaek, D. S., Sorensen, I. M., Schionning, H., Fjeld, T., Nykjaer, C., Larsen, S. M. U., Grzywacz, M., Mathiesen, T., Klausen, I., Hansen, O. O., Brendstrup-Brix, K., Linnet, K., Johansen, S. S., Fisher, P. M., Jensen, R. H., Knudsen, G. M.

Publikováno v: Madsen, M K, Petersen, A S, Stenbaek, D S, Sorensen, I M, Schionning, H, Fjeld, T, Nykjaer, C, Larsen, S M U, Grzywacz, M, Mathiesen, T, Klausen, I, Hansen, O O, Brendstrup-Brix, K, Linnet, K, Johansen, S S, Fisher, P M, Jensen, R H, Knudsen, G M & Madsen, M K 2022 ' Psilocybin-induced reduction in chronic cluster headache attack frequency correlates with changes in hypothalamic functional connectivity ' medRxiv . https://doi.org/10.1101/2022.07.10.22277414

Chronic cluster headache (CCH) is an excruciating disorder of unknown pathophysiology, but hypothalamic dysfunction has been implicated. CCH is difficult to treat but on a case-basis, the psychedelic compound psilocybin is said to have beneficial eff

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