Pharmacological TRPC6 inhibition improves survival and muscle function in mice with Duchenne muscular dystrophy.

Autor: Lin BL; Department of Cardiology., Shin JY; Department of Cardiology., Jeffreys WP; Department of Cardiology., Wang N; Department of Cardiology., Lukban CA; Department of Cardiology., Moorer MC; Department of Orthopaedics, and., Velarde E; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Baltimore, Maryland, USA., Hanselman OA; Department of Cardiology., Kwon S; Department of Cardiology., Kannan S; Department of Cardiology., Riddle RC; Department of Orthopaedics, and., Ward CW; Department of Orthopedics, University of Maryland, Baltimore, Maryland, USA., Pullen SS; Cardiometabolic Diseases Research and., Filareto A; Research Beyond Borders, Boehringer Ingelheim Pharmaceuticals, Ridgefield, Connecticut, USA., Kass DA; Department of Cardiology.; Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, Maryland, USA.

Publikováno v: JCI insight [JCI Insight] 2022 Oct 10; Vol. 7 (19). Date of Electronic Publication: 2022 Oct 10.