Výsledky vyhledávání - "Hans-Werner Fries"

Maturation of dendritic cells leads to up-regulation of cellular FLICE-inhibitory protein and concomitant down-regulation of death ligand–mediated apoptosis

Autor: Martin Leverkus, Henning Walczak, Alexander D. McLellan, Hans-Werner Fries, Gabi Terbeck, Eckhart Kämpgen, Eva-B. Bröcker

Publikováno v: Blood. 96:2628-2631

Dendritic cells (DCs) disappear from lymph nodes 1 to 2 days after antigen presentation, presumably by apoptosis. To evaluate the role of death ligands in elimination of DCs, we analyzed the sensitivity of human DCs to CD95 ligand (CD95L) and tumor n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f437a10130a59facdc2a4315b9b183da
https://doi.org/10.1182/blood.v96.7.2628

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Differential expression of Rel/NF-κB and octamer factors is a hallmark of the generation and maturation of dendritic cells

Autor: Annette Kolb-Mäurer, C. Scheicher, Eckhart Kämpgen, Petra Keikavoussi, Hans-Werner Fries, Edgar Serfling, Eva-B. Bröcker, Manfred Neumann

Publikováno v: Blood. 95:277-285

A key feature of maturation of dendritic cells is the down-regulation of antigen-processing and up-regulation of immunostimulatory capacities. To study the differential expression of transcription factors in this process, we investigated the nuclear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a15c3dadf416b9c7a3db113daf5427c
https://doi.org/10.1182/blood.v95.1.277.001k45_277_285

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Listeria monocytogenes-infected human dendritic cells: uptake and host cell response

Autor: Werner Goebel, Eva-Bettina Bröcker, Ivaylo Gentschev, Hans-Werner Fries, Eckhart Kämpgen, Annette Kolb-Mäurer, Franz Fiedler

Publikováno v: Infection and immunity. 68(6)

Dendritic cells (DCs) are potent antigen-presenting cells and play a crucial role in initiation and modulation of specific immune responses. Various pathogens are able to persist inside DCs. However, internalization of the gram-positive bacteriumList

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2677c4b180eb94124872db30da3613c
https://pubmed.ncbi.nlm.nih.gov/10816528

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The ins and outs of Raf kinases

Autor: Hans-Werner Fries, Günter Daum, Ulf R. Rapp, Jakob Troppmair, Iris Eisenmann-Tappe

Publikováno v: Trends in biochemical sciences. 19(11)

Raf kinases are signal-integrating enzymes that have the ability to switch tyrosine kinase signalling to serine/threonine phosphorylation and connect growth factor receptors with transcription factors. The connection involves a cascade of protein kin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa6347cc3fc0a862e6cc8fea0f2a84b
https://pubmed.ncbi.nlm.nih.gov/7855890

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