Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Hans-René Bjørsvik"'
Autor:
Shahin Sarowar, Davide Cirillo, Pablo Játiva, Mette Hartmark Nilsen, Sarah-Muheha Anni Otragane, Jan Heggdal, Frode Selheim, Valentín Ceña, Hans-René Bjørsvik, Per Øyvind Enger
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Metastatic tumors with moderate radiosensitivity account for most cancer-related deaths, highlighting the limitations of current radiotherapy regimens. The xCT-inhibitor sulfasalazine (SAS) sensitizes cancer cells to radiotherapy by blocking cystine
Externí odkaz:
https://doaj.org/article/dd9a9a4b0be142ba87cf11186be1469d
Publikováno v:
European Journal of Organic Chemistry. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3100fc10e48fef4663300cc6f9502f1
https://doi.org/10.1002/ejoc.202201504
https://doi.org/10.1002/ejoc.202201504
Publikováno v:
European Journal of Organic Chemistry
A selective oxidative Heck cross-coupling method was developed and optimized as a pivotal step for a synthetic route leading to the trans-stilbene framework. The developed method and synthesis were needed in a SAR study in progress that concerned des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246e368f223dfdae4f6c5559226cba41
https://doi.org/10.1002/ejoc.202100493
https://doi.org/10.1002/ejoc.202100493
Publikováno v:
Chemmedchem
ChemMedChem
ChemMedChem
The xCT antiporter is a cell membrane protein involved in active counter‐transportation of glutamate (outflux) with cystine (influx) over the human cell membrane. This feature makes the xCT antiporter a crucial element of the biosynthesis of the vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784c2f482aeb5444f68863dfa27aae56
https://doi.org/10.1002/cmdc.202100204
https://doi.org/10.1002/cmdc.202100204
Publikováno v:
Advanced Synthesis and Catalysis
A general and selective Pd-catalyzed cross-coupling of aromatic boronic acids with vinyl-imidazoles is disclosed. Unlike most cross-coupling reactions, this method operates well in absence of bases avoiding the formation of by-products. The reactivit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f8ea056cf05ed0cf303fb988f34ba8
https://doi.org/10.1002/adsc.202000909
https://doi.org/10.1002/adsc.202000909
Publikováno v:
ChemMedChem. 15:862-870
A previously designed and developed 12-step total synthesis that includes [1,1'-biphenyl]-2-amine and carbazole intermediates and that ultimately produces the carbazole alkaloid carbazomycin G was exploited as a screening compound library with the go
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c380f24c6cfd7ecf61ab695b9d9b695e
https://doi.org/10.1002/cmdc.202000066
https://doi.org/10.1002/cmdc.202000066
Publikováno v:
e202200437
European Journal of Organic Chemistry
European Journal of Organic Chemistry
A selective and high-rate Ru-catalyzed cross-metathesis reaction of alkenes with vinylimidazole is disclosed. Cross-metathesis is known to operate less efficiently on N-heterocycles, but through optimization by means of statistical experimental desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2fd5e5fbda12c9ba86360ac13733bc
https://hdl.handle.net/11250/3045327
https://hdl.handle.net/11250/3045327
Autor:
Stephanie Schwab, Katharina Sarnow, Eirin Alme, Roland Goldbrunner, Hans-René Bjørsvik, Rolf Bjerkvig
Publikováno v:
Neuro Oncol
BACKGROUND Although withdrawn from the market due to cardiotoxicity, we showed that the antipsychotic drug Thioridazine shows chemosensitizing effects in combination with Temozolomide (TMZ) for the treatment of glioblastoma multiforme (GBM). Based on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6e9a68e6212eb43c444713a7324aea
https://europepmc.org/articles/PMC8598767/
https://europepmc.org/articles/PMC8598767/
Publikováno v:
Reaction Chemistry & Engineering. 4:41-51
Primary and benzylic alcohols were cost-effectively transformed into their corresponding nitriles using a classical batch approach and a continuous flow process implemented on a multi-jet oscillating disk (MJOD) reactor platform. The alcohols as subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44d5011428b9a60543b0e391e9ffaf9
https://doi.org/10.1039/c8re00129d
https://doi.org/10.1039/c8re00129d
Autor:
Shahin Sarowar, Davide Cirillo, Pablo Jativa, Mette H. Nilsen, Sarah-Muheha A. Otragane, Jan I. Heggdal, Frode Selheim, Valentín Ceña, Hans-René Bjørsvik, Per Øyvind Enger
Publikováno v:
Cancer Research. 82:214-214
Metastatic tumors with moderate radiosensitivity account for most cancer-related deaths, highlighting the limitations of current radiotherapy regimens. The xCT-inhibitor sulfasalazine (SAS) sensitizes cancer cells by blocking xCT-mediated cystine upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::093f45b7ffb519e3e0e2899d38055d7e
https://doi.org/10.1158/1538-7445.am2022-214
https://doi.org/10.1158/1538-7445.am2022-214