Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hans-Peter Luther"'
Publikováno v:
Voigtsberger, Stefanie; Bartsch, Holger; Baumann, Gert; Luther, Hans Peter (2009). Cell type-specific expression of endogenous cardiac Troponin I antisense RNA in the neonatal rat heart. Molecular and cellular biochemistry, 324(1-2), pp. 1-11. Springer 10.1007/s11010-008-9974-3
Since the number of detected natural antisense RNA is growing, investigations upon the expression pattern of the antisense RNA become more important. As we focused our work on natural occurring antisense transcripts in human and rat heart tissues, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1889c6eb14a72ef10170b2f60c1b04
http://doc.rero.ch/record/319100/files/11010_2008_Article_9974.pdf
http://doc.rero.ch/record/319100/files/11010_2008_Article_9974.pdf
Publikováno v:
Journal of Cellular Biochemistry. 94:848-855
Naturally occurring antisense RNA has been detected for a range of eukaryotic genes. Its abundance compared to levels of its complementary sense mRNA appears to be a factor indicating its possible regulatory function. In previous studies, we detected
Publikováno v:
Journal of Cellular Biochemistry. 85:198-207
Natural antisense RNA is now thought to regulate, at least in part, a growing number of eukaryotic genes. It is becoming increasingly apparent that such endogenous antisense RNA molecules may modulate gene expression in a manner analogous to syntheti
Publikováno v:
Journal of Cellular Biochemistry. 80:596-605
Naturally occurring antisense RNA has the potential to form a duplex with its complementary sense mRNA, thereby regulating protein expression. Previously, we demonstrated considerable amounts of endogenous antisense RNA for both alpha- and beta-myosi
Autor:
Hans Peter Luther, Svenia Podlowski, Wolfgang Schulze, Rosemarie Morwinski, Igor Buchwalow, Gert Baumann
Publikováno v:
Molecular and Cellular Biochemistry. 224:69-79
Three α1AR subtypes have been cloned so far and are designated as α1a, α1b, and α1d. Organspecific distribution pattern and subtype-specific effects are known but not fully understood. To address a cell-type specific expression pattern in the hea
Autor:
Gerd Wallukat, Margret R. Hoehe, Karla Köpke, Svenia Podlowski, Astrid Speer, Roland Hetzer, Johannes Müller, Gert Baumann, Stephan B. Felix, Peter Bramlage, Hans Peter Luther, Katrin Wenzel
Publikováno v:
Scopus-Elsevier
A substantial body of evidence suggests involvement of the human beta1-adrenoceptor (beta1-AR) gene in the pathophysiology of dilated cardiomyopathy (DCM), a severe heart disease of significant public health impact. Beta1-AR-mediated signal transduct
Autor:
Gert Baumann, Ingo Morano, Leonidas G. Baltas, Hannelore Haase, Hans Peter Luther, Hagen D. Schulte, Oliver Ritter
Publikováno v:
Journal of Molecular Medicine. 77:677-685
The adult rodent heart adapts to increased work load by reexpression of its fetal genes, for example, beta-myosin heavy chain (MHC), in order to improve contractile function. However, the human ventricle regulates contractility by expression of atria
Publikováno v:
Circulation. 98:2470-2476
Background —Autoantibodies directed against the β 1 -adrenergic receptor have been described in patients with dilated cardiomyopathy. These autoantibodies exert an agonistic, chronotropic effect on spontaneously beating cultured neonatal rat cardi
Publikováno v:
Journal of Cellular Biochemistry. 70:110-120
Analysis of mRNA by Northern blot and reverse transcription–polymerase chain reaction demonstrated the expression of sense and considerable amounts of naturally occurring antisense mRNA for β-myosin heavy chain (MHC) and α-MHC in the neonatal rat
Publikováno v:
Journal of Cellular Biochemistry. 64:458-465
It is generally accepted that mechanical stress of cardiomyocytes increases RNA and protein synthesis of myosin heavy chain (MHC) quantitatively but it is still a matter of debate whether MHC gene expression is also changed qualitatively. We investig