Zobrazeno 1 - 10
of 327
pro vyhledávání: '"Hans-Peter Horny"'
Autor:
Johannes Lübke, Nicole Naumann, Oliver Hoffmann, Hans-Peter Horny, Karl Sotlar, Martina Rudelius, Georgia Metzgeroth, Alice Fabarius, Wolf-Karsten Hofmann, Andreas Reiter, Juliana Schwaab
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract In 70 patients with KIT D816V positive systemic mastocytosis (SM) including 36 patients with advanced SM (AdvSM), we correlated the extent of reported mucosal mast cell ([m]MC) infiltration of the upper and/or lower gastrointestinal tract (U
Externí odkaz:
https://doaj.org/article/401bed6d276b43f0807e3552a3d9913f
Autor:
Johannes Lübke, Nicole Naumann, Georgia Metzgeroth, Alice Fabarius, Timo Brand, Hans-Peter Horny, Karl Sotlar, Wolf-Karsten Hofmann, Juliana Schwaab, Andreas Reiter
Publikováno v:
HemaSphere, Vol 7, p e472819b (2023)
Externí odkaz:
https://doaj.org/article/340457ea6c1f4b7cbd4ba14f78640ecd
Autor:
Julia Riffel, Johannes Lübke, Nicole Naumann, Sebastian Kreil, Georgia Metzgeroth, Alice Fabarius, Karl Sotlar, Hans-Peter Horny, Mohamad Jawhar, Daniel Overhoff, Stefan Schoenberg, Wolf-Karsten Hofmann, Thomas Henzler, Juliana Schwaab, Andreas Reiter, Philipp Riffel
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Systemic mastocytosis (SM) is characterized by multifocal accumulation of neoplastic mast cells (MCs), predominately affecting the bone marrow (BM). Imaging with computed tomography (CT) is used for assessment of bone mineral density and str
Externí odkaz:
https://doaj.org/article/2c12322153304911a38febee511dbcc1
Autor:
Nicole Naumann, Martina Rudelius, Johannes Lübke, Deborah Christen, Jakob Bresser, Karl Sotlar, Georgia Metzgeroth, Alice Fabarius, Wolf-Karsten Hofmann, Jens Panse, Hans-Peter Horny, Nicholas C. P. Cross, Andreas Reiter, Juliana Schwaab
Publikováno v:
Cancers, Vol 16, Iss 3, p 593 (2024)
Within our nationwide registry, we identified a KIT D816V mutation (KIT D816Vpos.) in 280/299 (94%) patients with advanced systemic mastocytosis (AdvSM). Age, cytopenias and the presence of additional somatic mutations confer inferior overall surviva
Externí odkaz:
https://doaj.org/article/4102360a4f7e43d58f625f4153e3774d
Autor:
Peter Valent, Cem Akin, Michel Arock, Karoline V. Gleixner, Hildegard Greinix, Olivier Hermine, Hans-Peter Horny, Daniel Ivanov, Alberto Orfao, Werner Rabitsch, Andreas Reiter, Axel Schulenburg, Karl Sotlar, Wolfgang R. Sperr, Celalettin Ustun
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 20, p 15125 (2023)
Advanced systemic mastocytosis (SM) is a heterogeneous group of myeloid neoplasms characterized by an uncontrolled expansion of mast cells (MC) in one or more internal organs, SM-induced tissue damage, and poor prognosis. Advanced SM can be categoriz
Externí odkaz:
https://doaj.org/article/6cb7db1987fb4a19b16cbf0a80918070
Autor:
Michael Willmann, Vilma Yuzbasiyan-Gurkan, Laura Marconato, Mauro Dacasto, Emir Hadzijusufovic, Olivier Hermine, Irina Sadovnik, Susanne Gamperl, Mathias Schneeweiss-Gleixner, Karoline V. Gleixner, Thomas Böhm, Barbara Peter, Gregor Eisenwort, Richard Moriggl, Zhixiong Li, Mohamad Jawhar, Karl Sotlar, Erika Jensen-Jarolim, Veronika Sexl, Hans-Peter Horny, Stephen J. Galli, Michel Arock, David M. Vail, Matti Kiupel, Peter Valent
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2021)
Mast cell neoplasms are one of the most frequently diagnosed malignancies in dogs. The clinical picture, course, and prognosis vary substantially among patients, depending on the anatomic site, grade and stage of the disease. The most frequently invo
Externí odkaz:
https://doaj.org/article/4d0b2c0063b54593ba1b2814f43e664c
Autor:
Peter Valent, Cem Akin, Karin Hartmann, Ivan Alvarez-Twose, Knut Brockow, Olivier Hermine, Marek Niedoszytko, Juliana Schwaab, Jonathan J. Lyons, Melody C. Carter, Hanneke Oude Elberink, Joseph H. Butterfield, Tracy I. George, Georg Greiner, Celalettin Ustun, Patrizia Bonadonna, Karl Sotlar, Gunnar Nilsson, Mohamad Jawhar, Frank Siebenhaar, Sigurd Broesby-Olsen, Selim Yavuz, Roberta Zanotti, Magdalena Lange, Boguslaw Nedoszytko, Gregor Hoermann, Mariana Castells, Deepti H. Radia, Javier I. Muñoz-Gonzalez, Wolfgang R. Sperr, Massimo Triggiani, Hanneke C. Kluin-Nelemans, Stephen J. Galli, Lawrence B. Schwartz, Andreas Reiter, Alberto Orfao, Jason Gotlib, Michel Arock, Hans-Peter Horny, Dean D. Metcalfe
Publikováno v:
HemaSphere, Vol 5, Iss 11, p e646 (2021)
Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract. The World Health Organization c
Externí odkaz:
https://doaj.org/article/baa6c70f9bed4d09abd7657782291f35
Autor:
Christof Wilke, Martina Blaschke, Annette Lamersdorf, Christina Heppner, Michael Metz, Hans-Peter Horny, Undine Lippert, Heide Siggelkow
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101023- (2021)
Externí odkaz:
https://doaj.org/article/9f24aa91221c4cba8862caab021aec67
Autor:
Anne Sophie Kubasch, Georg-Nikolaus Franke, Ali Aldaoud, Konstantin Weibl, Madlen Jentzsch, Osama Sabri, Hans-Peter Horny, Falko Fend, Gerhard Behre, Uwe Platzbecker, Vladan Vucinic
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Mast cell sarcoma comprises a rare aggressive mast cell neoplasia with histological, clinical, and genetic features distinct from other mast cell neoplasm. Until now, prognosis is still poor due to high rates of progression to mast cell leukemia and
Externí odkaz:
https://doaj.org/article/8ee55102aac04e13ae52ac767fdd704f
Autor:
Celalettin Ustun, Elizabeth Morgan, Erica E. M. Moodie, Sheeja Pullarkat, Cecilia Yeung, Sigurd Broesby‐Olsen, Robert Ohgami, Young Kim, Wolfgang Sperr, Hanne Vestergaard, Dong Chen, Philip M. Kluin, Michelle Dolan, Krzysztof Mrózek, David Czuchlewski, Hans‐Peter Horny, Tracy I. George, Thomas Kielsgaard Kristensen, Nam K. Ku, Cecilia Arana Yi, Michael Boe Møller, Guido Marcucci, Linda Baughn, Ana‐Iris Schiefer, J. R. Hilberink, Vinod Pullarkat, Ryan Shanley, Jessica Kohlschmidt, Janie Coulombe, Amandeep Salhotra, Lori Soma, Christina Cho, Michael A. Linden, Cem Akin, Jason Gotlib, Gregor Hoermann, Jason Hornick, Ryo Nakamura, Joachim Deeg, Clara D. Bloomfield, Daniel Weisdorf, Mark R. Litzow, Peter Valent, Gerwin Huls, Miguel‐Angel Perales, Gautam Borthakur
Publikováno v:
Cancer Medicine, Vol 7, Iss 9, Pp 4447-4455 (2018)
Abstract Background Although the prognosis of core‐binding factor (CBF) acute myeloid leukemia (AML) is better than other subtypes of AML, 30% of patients still relapse and may require allogeneic hematopoietic cell transplantation (alloHCT). Howeve
Externí odkaz:
https://doaj.org/article/094eb1a2e98b464ea81e0fe6a9fdcc3c