Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Hans-Peter Holthoff"'
Autor:
Clara Wenhart, Hans-Peter Holthoff, Andreas Reimann, Zhongmin Li, Julia Faßbender, Martin Ungerer
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Rheumatoid arthritis (RA) is a systemic inflammatory autoimmune disease which affects primarily the joints. Peptides of several proteins have shown an effect in some experimental animal models of RA. We investigated arthritis development in
Externí odkaz:
https://doaj.org/article/50b17eb211e643d9b23f8b73fc7115ee
Autor:
Jennifer R. Richardson, Ralph Götz, Vanessa Mayr, Martin J. Lohse, Hans-Peter Holthoff, Martin Ungerer
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Objective We investigated blood samples from fully SARS-CoV2-vaccinated subjects and from previously positive tested patients up to one year after infection with SARS-CoV2, and compared short- and long-term T cell and antibody responses, with a speci
Externí odkaz:
https://doaj.org/article/461a758c7d4a4169a226bb4f202935f0
Autor:
Zhongmin Li, Martin Ungerer, Julia Faßbender, Clara Wenhart, Hans-Peter Holthoff, Goetz Muench
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
The standard histological processing procedure, which produces excellent staining of sections for most tissues, fails to yield satisfactory results in adult mouse orbits or eyeballs. Here, we show that a protocol using tissue block staining and domes
Externí odkaz:
https://doaj.org/article/8f549b28924148bd8a55bba32f279f4e
Autor:
Teresa L. Krammer, Stephan Zeibig, Waltraud C. Schrottmaier, Anita Pirabe, Silvia Goebel, Andreas B. Diendorfer, Hans-Peter Holthoff, Alice Assinger, Matthias Hackl
Publikováno v:
Cells, Vol 11, Iss 8, p 1254 (2022)
Dysregulation of platelet function is causally connected to thrombus formation and cardiovascular diseases. Therefore, assessing platelet reactivity is crucial. However, current platelet function tests come with pitfalls, limiting clinical use. Plasm
Externí odkaz:
https://doaj.org/article/f22953e7465e427f8d89447c8e0eb377
Autor:
Marion Mussbacher, Teresa L. Krammer, Stefan Heber, Waltraud C. Schrottmaier, Stephan Zeibig, Hans-Peter Holthoff, David Pereyra, Patrick Starlinger, Matthias Hackl, Alice Assinger
Publikováno v:
Cells, Vol 9, Iss 8, p 1915 (2020)
Blood-derived microRNA signatures have emerged as powerful biomarkers for predicting and diagnosing cardiovascular disease, cancer, and metabolic disorders. Platelets and platelet-derived microvesicles are a major source of microRNAs. We have previou
Externí odkaz:
https://doaj.org/article/519f71a3c9324273b77233c43a2f4719
Autor:
Valérie Boivin-Jahns, Kerstin Uhland, Hans-Peter Holthoff, Niklas Beyersdorf, Vladimir Kocoski, Thomas Kerkau, Götz Münch, Martin J Lohse, Martin Ungerer, Roland Jahns
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201160 (2018)
RATIONALE:Despite advances in pharmacotherapy, heart failure still incurs significant morbidity and mortality. Stimulating antibodies directed against the secondextracellular loop of the human ß1-adrenergic receptor (anti-ß1EC2) cause myocyte damag
Externí odkaz:
https://doaj.org/article/d7cea84fe6d649979c26f8103e1de8d4
Autor:
Silvia Goebel, Zhongmin Li, Jasmin Vogelmann, Hans-Peter Holthoff, Heidrun Degen, Dirk M Hermann, Meinrad Gawaz, Martin Ungerer, Götz Münch
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e66960 (2013)
OBJECTIVES: We examined the effect of Revacept, an Fc fusion protein which is specifically linked to the extracellular domain of glycoprotein VI (GPVI), on thrombus formation after vessel wall injury and on experimental stroke in mice. BACKGROUND: Se
Externí odkaz:
https://doaj.org/article/937b3af4b40a4cc6996c43a0a8fe2f9b
Autor:
Martin Ungerer, Zhongmin Li, Christine Baumgartner, Silvia Goebel, Jasmin Vogelmann, Hans-Peter Holthoff, Meinrad Gawaz, Götz Münch
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71193 (2013)
AIMS: Glycoprotein VI (GPVI) is a key platelet receptor which mediates plaque-induced platelet activation and consecutive atherothrombosis, but GPVI is also involved in platelet-mediated atheroprogression. Therefore, interference in GPVI-mediated pla
Externí odkaz:
https://doaj.org/article/7f93eb77fe3d482d804c1b79735edc17
Autor:
Andreas Reimann, Zhongmin Li, Silvia Goebel, Julia Fassbender, Hans-Peter Holthoff, Meinrad Gawaz, Götz Münch, Martin Ungerer
Publikováno v:
Heart International, Vol 11, Iss 1, Pp 0-0 (2016)
BackgroundThrombolytic therapy with recombinant tissue plasminogen activator (rtPA) remains the only approved medication for acute ischemic stroke, but incurs significant bleeding risks. Therefore, approaches to combine lower doses of thrombolytic th
Externí odkaz:
https://doaj.org/article/d2f98ed9def6452f95059e9174aa3bac
Autor:
Martin Ungerer, Silvia Wagner, Julia Ullrich, Hans-Peter Holthoff, Zhongmin Li, Andreas Bültmann, Götz Münch
Publikováno v:
Heart International, Vol 7, Iss 2, Pp e12-e12 (2012)
The ABCG1 protein is centrally involved in reverse cholesterol transport from the vessel wall. Investigation of the effects of ABCG1 overexpression or knockdown in vivo has produced controversial results and strongly depended on the gene intervention
Externí odkaz:
https://doaj.org/article/7f764985fd694962b7bcd6ba46351428