Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Hans-Michael Kaltenbach"'
Publikováno v:
BMC Bioinformatics, Vol 24, Iss S1, Pp 1-27 (2023)
Abstract Background Synthetic biologists use and combine diverse biological parts to build systems such as genetic circuits that perform desirable functions in, for example, biomedical or industrial applications. Computer-aided design methods have be
Externí odkaz:
https://doaj.org/article/72293d81f54c47938469b21e84e3d803
Autor:
Julia Deichmann, Sara Bachmann, Marie-Anne Burckhardt, Marc Pfister, Gabor Szinnai, Hans-Michael Kaltenbach
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 2, p e1010289 (2023)
Accurate treatment adjustment to physical activity (PA) remains a challenging problem in type 1 diabetes (T1D) management. Exercise-driven effects on glucose metabolism depend strongly on duration and intensity of the activity, and are highly variabl
Externí odkaz:
https://doaj.org/article/3e2656e76b3c42d69a2b2e1d486ccdf4
Autor:
Julia Deichmann, Sara Bachmann, Marie-Anne Burckhardt, Gabor Szinnai, Hans-Michael Kaltenbach
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Regular exercise is beneficial and recommended for people with type 1 diabetes, but increased glucose demand and changes in insulin sensitivity require treatment adjustments to prevent exercise-induced hypoglycemia. Several different adjustment strat
Externí odkaz:
https://doaj.org/article/ba745684db3a45e1bc022e57b6b19049
Autor:
Anja Henseleit, Carolin Pohl, Hans-Michael Kaltenbach, Karina Hettwer, Kirsten Simon, Steffen Uhlig, Natalie Haustein, Thomas Bley, Elke Boschke
Publikováno v:
Biosensors, Vol 5, Iss 1, Pp 27-36 (2015)
We used the interaction between human serum albumin (HSA) and a high-affinity antibody to evaluate binding affinity measurements by the bench-top liSPR system (capitalis technology GmbH). HSA was immobilized directly onto a carboxylated sensor layer,
Externí odkaz:
https://doaj.org/article/8110307a787e4cc0a9d8b118247291aa
Relating metabolite and enzyme abundances to metabolic fluxes requires reaction kinetics, core elements of dynamic and enzyme cost models. However, kinetic parameters have been measured only for a fraction of all known enzymes, and the reliability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92c2cc9f73fdc8a1ade9addd5e08a283
https://doi.org/10.1101/2023.03.08.531697
https://doi.org/10.1101/2023.03.08.531697
Autor:
Furkan Gökçe, Alicia Kaestli, Christian Lohasz, Martina de Geus, Hans‐Michael Kaltenbach, Kasper Renggli, Beat Bornhauser, Andreas Hierlemann, Mario Modena
Publikováno v:
Advanced Healthcare Materials, 12 (6)
Despite increasing survival rates of pediatric leukemia patients over the past decades, the outcome of some leukemia subtypes has remained dismal. Drug sensitivity and resistance testing on patient-derived leukemia samples provide important informati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9583b17ef7eb2d68e048d3bbb1c722d3
Publikováno v:
IFAC-PapersOnLine, 54 (15)
Insulin sensitivity is an important physiological parameter for determining insulin requirements for patients with type 1 diabetes. In addition to being highly variable between patients, insulin sensitivity increases substantially during exercise and
Autor:
Hans-Michael Kaltenbach
Publikováno v:
SASB
Electronic notes in theoretical computer science, 350
Proceedings of SASB 2018, the Ninth International Workshop on Static Analysis and Systems Biology
Electronic notes in theoretical computer science, 350
Proceedings of SASB 2018, the Ninth International Workshop on Static Analysis and Systems Biology
The Jacobian matrix of a dynamic system and its principal minors play a prominent role in the study of qualitative dynamics and bifurcation analysis. When interpreting the Jacobian as an adjacency matrix of an interaction graph, its principal minors
Publikováno v:
Yeast. 37:336-347
Saccharomyces cerevisiae cells grown in a small volume of chemically defined media neither reach the desired cell density nor grow at a fast enough rate to scale down the volume and increase the sample number of classical biochemical assays, as the d
Publikováno v:
IFAC-PapersOnLine, 53 (2)
21th IFAC World Congress. Proceedings
21th IFAC World Congress. Proceedings
Deterministic dynamic models play a crucial role in elucidating the function of biological networks. However, the underlying biological mechanisms are often only partially known, and different biological hypotheses on the unknown molecular mechanisms