Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Hans-Martin Pogoda"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The vertebral column, with the centra as its iteratively arranged building blocks, represents the anatomical key feature of the vertebrate phylum. In contrast to amniotes, where vertebrae are formed from chondrocytes and osteoblasts deriving from the
Externí odkaz:
https://doaj.org/article/88cf3704eef04f3d949b6271b1354f16
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101034- (2021)
Externí odkaz:
https://doaj.org/article/af75db5fc48b4106aa4aef04314b9c78
Autor:
Amelie T van der Ven, Birgit Kobbe, Stefan Kohl, Shirlee Shril, Hans-Martin Pogoda, Thomas Imhof, Hadas Ityel, Asaf Vivante, Jing Chen, Daw-Yang Hwang, Dervla M Connaughton, Nina Mann, Eugen Widmeier, Mary Taglienti, Johanna Magdalena Schmidt, Makiko Nakayama, Prabha Senguttuvan, Selvin Kumar, Velibor Tasic, Elijah O Kehinde, Shrikant M Mane, Richard P Lifton, Neveen Soliman, Weining Lu, Stuart B Bauer, Matthias Hammerschmidt, Raimund Wagener, Friedhelm Hildebrandt
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191224 (2018)
Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause (40-50%) of chronic kidney disease (CKD) in children. About 40 monogenic causes of CAKUT have so far been discovered. To date less than 20% of CAKUT cases can be e
Externí odkaz:
https://doaj.org/article/2bc11b7231c74bacbf98e8696e293ebc
Autor:
Gerhard Sengle, Matthias Hammerschmidt, Douglas R. Keene, S. Luetke, Wilhelm Bloch, Julia Hatzold, Hans-Martin Pogoda, S. Richetti, D. Welcker, T. Ramezani, F. Zaucke, Jin-Li Zhang
Publikováno v:
Matrix Biol
Hemicentins are large proteins of the extracellular matrix that belong to the fibulin family and play pivotal roles during development and homeostasis of a variety of invertebrate and vertebrate tissues. However, bona fide interaction partners of hem
Autor:
Andrea Nist, Thorsten Stiewe, Yanpeng Ren, Robert Liefke, Clara Simon, Sabrina K. Phanor, Bastian Stielow, Iris Rohner, Martha L. Bulyk, Yinghua Cao, Yang Shi, Matthias Hammerschmidt, Zhanxin Wang, Yuqiao Zhou, Hans-Martin Pogoda, Junyi Jiang
Publikováno v:
Science Advances
SAMD1 is a newly identified repressive CpG island regulator.
CpG islands (CGIs) are key regulatory DNA elements at most promoters, but how they influence the chromatin status and transcription remains elusive. Here, we identify and characterize
CpG islands (CGIs) are key regulatory DNA elements at most promoters, but how they influence the chromatin status and transcription remains elusive. Here, we identify and characterize
Autor:
Koichi Kawakami, Hans-Martin Pogoda, Jerónimo R. Miranda-Rodríguez, Indra Wibowo, Filipe Pinto-Teixeira, Matthias Hammerschmidt, Augusto Borges, Hernán López-Schier
Mutations in the transcriptional co-activator Eya1 cause branchio-oto-renal syndrome (BOR) in humans. BOR has an incidence of 1/40,000 and is characterized by congenital branchial fistulas, malformations of the inner ear and kidney hypoplasia. Therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061e9931d471bc98b39532fcea9488fc
https://doi.org/10.1101/2021.01.27.428404
https://doi.org/10.1101/2021.01.27.428404
Publikováno v:
Dev Biol
We have previously shown that the Kunitz-type serine protease inhibitor Spint1a, also named Hai1a, is required in the zebrafish embryonic epidermis to restrict the activity of the type II transmembrane serine protease (TTSP) Matriptase1a / St14a, the
Autor:
Michel Michaelides, Costin Leu, Neringa Jurkute, Susanne Motameny, Anthony T. Moore, Andrew R. Webster, Holger Thiele, Gavin Arno, Wolfgang Höhne, Marcela Votruba, Gudrun Nürnberg, Anthony G. Robson, Matthias Hammerschmidt, Patrick Yu-Wai-Man, Kate Powell, Janine Altmüller, Mohammad R. Toliat, Peter Nürnberg, Hans-Martin Pogoda
Publikováno v:
Ann Neurol
Annals of neurology, vol 86, iss 3
Annals of neurology, vol 86, iss 3
OBJECTIVE: Autosomal dominant optic atrophy (ADOA) starts in early childhood with loss of visual acuity and color vision deficits. OPA1 mutations are responsible for the majority of cases, but in a portion of patients with a clinical diagnosis of ADO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6129cb11ca2c5153292922d2c085f4e1
Autor:
Iris Riedl-Quinkertz, Joshua S. Waxman, Hans Martin Pogoda, Jacek Topczewski, Stefan Schulte-Merker, Matthias Hammerschmidt, Rodney M. Dale, Heiko Löhr
Publikováno v:
Development (Cambridge), 145(9). Company of Biologists Ltd
Zebrafish mutants with increased retinoic acid (RA) signaling due to the loss of the RA-inactivating enzyme Cyp26b1 develop a hyper-mineralized spine with gradually fusing vertebral body precursors (centra). However, the underlying cellular mechanism
Autor:
Richard P. Lifton, Elijah O. Kehinde, Shirlee Shril, Amelie T. van der Ven, Mary E. Taglienti, Raimund Wagener, Weining Lu, Neveen A. Soliman, Asaf Vivante, Birgit Kobbe, Makiko Nakayama, Selvin Kumar, Shrikant M. Mane, Nina Mann, Jing Chen, Stuart B. Bauer, Hadas Ityel, Thomas Imhof, Hans-Martin Pogoda, Dervla M. Connaughton, Eugen Widmeier, Johanna Magdalena Schmidt, Velibor Tasic, Daw-Yang Hwang, Friedhelm Hildebrandt, Prabha Senguttuvan, Stefan Kohl, Matthias Hammerschmidt
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 1, p e0191224 (2018)
PLoS ONE, Vol 13, Iss 1, p e0191224 (2018)
Congenital anomalies of the kidney and urinary tract (CAKUT) are the most common cause (40-50%) of chronic kidney disease (CKD) in children. About 40 monogenic causes of CAKUT have so far been discovered. To date less than 20% of CAKUT cases can be e