Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Hans-Martin Jack"'
Autor:
Lu Zhang, Hsiu-Hsin Cheng, Nadine Krüger, Bojan Hörnich, Luise Graichen, Alexander S Hahn, Sebastian R Schulz, Hans-Martin Jäck, Metodi V Stankov, Georg M N Behrens, Marcel A Müller, Christian Drosten, Onnen Mörer, Martin Sebastian Winkler, ZhaoHui Qian, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
PLoS Pathogens, Vol 20, Iss 11, p e1012653 (2024)
The COVID-19 pandemic, caused by SARS-CoV-2, demonstrated that zoonotic transmission of animal sarbecoviruses threatens human health but the determinants of transmission are incompletely understood. Here, we show that most spike (S) proteins of horse
Externí odkaz:
https://doaj.org/article/dd59c1eaa458436d8dfc21d5782cf2ec
Autor:
Anupriya Aggarwal, Alberto Stella, Gregory Walker, Anouschka Akerman, Vanessa Milogiannakis, Fabienne Brilot, Supavadee Amatayakul-Chantler, Nathan Roth, Germano Coppola, Peter Schofield, Jennifer Jackson, Helen Lenthall, Ohan Mazigi, David Langley, Yonghui Lu, Charles Forster, Samantha McAllery, Vennila Mathivanan, Christina Fitcher, Alexandra Carey Hoppe, C. Mee Ling Munier, Hans-Martin Jack, Deborah Cromer, David Darley, Gail Matthews, Daniel Christ, David Khoury, Miles Davenport, William Rawlinson, Anthony Kelleher, Stuart Turville
Genetically distinct viral variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been recorded since January 2020. Over this time global vaccine programs have been introduced, contributing to lowered COVID-19 hospitalisation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf5fd572c3a5b28731191620ce8ce65
https://doi.org/10.21203/rs.3.rs-1207364/v1
https://doi.org/10.21203/rs.3.rs-1207364/v1
Autor:
Ariful Haque Abir, Leonie Weckwerth, Artur Wilhelm, Jana Thomas, Clara M. Reichardt, Luis Munoz, Simon Völkl, Uwe Appelt, Markus Mroz, Raluca Niesner, Anja Hauser, Rebecca Sophie Fischer, Katharina Pracht, Hans-Martin Jäck, Georg Schett, Gerhard Krönke, Dirk Mielenz
Publikováno v:
Molecular Metabolism, Vol 87, Iss , Pp 101981- (2024)
Objective: The metabolism of different cells within the same microenvironment can differ and dictate physiological or pathological adaptions. Current single-cell analysis methods of metabolism are not label-free. Methods: The study introduces a label
Externí odkaz:
https://doaj.org/article/5b381a534cf04e8f9f71a6a2532ba488
Autor:
Nianzhen Chen, Katharina Emma Decker, Sebastian R. Schulz, Amy Kempf, Inga Nehlmeier, Anna-Sophie Moldenhauer, Alexandra Dopfer-Jablonka, Georg M. N. Behrens, Metodi V. Stankov, Luis Manthey, Hans-Martin Jäck, Markus Hoffmann, Stefan Pöhlmann, Prerna Arora
Publikováno v:
Vaccines, Vol 12, Iss 11, p 1236 (2024)
New SARS-CoV-2 lineages continue to evolve and may exhibit new characteristics regarding host cell entry efficiency and potential for antibody evasion. Here, employing pseudotyped particles, we compared the host cell entry efficiency, ACE2 receptor u
Externí odkaz:
https://doaj.org/article/0c55e3d4b4ff40df90a59f5934cc15f5
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1131 (2024)
Introducing genetic material into hard-to-transfect mammalian cell lines and primary cells is often best achieved through retroviral infection. An ideal retroviral vector should offer a compact, selectable, and screenable marker while maximizing tran
Externí odkaz:
https://doaj.org/article/5813c95a2a794d7ebaedb953f0816c93
Autor:
Theresa E.H. Bierling, Amelie Gumann, Shannon R. Ottmann, Sebastian R. Schulz, Leonie Weckwerth, Jana Thomas, Arne Gessner, Magdalena Wichert, Frederic Kuwert, Franziska Rost, Manuela Hauke, Tatjana Freudenreich, Dirk Mielenz, Hans-Martin Jäck, Katharina Pracht
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113739- (2024)
Summary: Glucose uptake increases during B cell activation and antibody-secreting cell (ASC) differentiation, but conflicting findings prevent a clear metabolic profile at different stages of B cell activation. Deletion of the glucose transporter typ
Externí odkaz:
https://doaj.org/article/a98e110be8b745b0865c6927784df68d
Autor:
Lu Zhang, Alexandra Dopfer-Jablonka, Inga Nehlmeier, Amy Kempf, Luise Graichen, Noemí Calderón Hampel, Anne Cossmann, Metodi V. Stankov, Gema Morillas Ramos, Sebastian R. Schulz, Hans-Martin Jäck, Georg M. N. Behrens, Stefan Pöhlmann, Markus Hoffmann
Publikováno v:
Vaccines, Vol 12, Iss 5, p 487 (2024)
Transmissibility and immune evasion of the recently emerged, highly mutated SARS-CoV-2 BA.2.87.1 are unknown. Here, we report that BA.2.87.1 efficiently enters human cells but is more sensitive to antibody-mediated neutralization than the currently d
Externí odkaz:
https://doaj.org/article/cd69a4083c014053bc288930db5d3c65
Autor:
Romain Rouet, Jake Y. Henry, Matt D. Johansen, Meghna Sobti, Harikrishnan Balachandran, David B. Langley, Gregory J. Walker, Helen Lenthall, Jennifer Jackson, Stephanie Ubiparipovic, Ohan Mazigi, Peter Schofield, Deborah L. Burnett, Simon H. J. Brown, Marianne Martinello, Bernard Hudson, Nicole Gilroy, Jeffrey J. Post, Anthony Kelleher, Hans-Martin Jäck, Christopher C. Goodnow, Stuart G. Turville, William D. Rawlinson, Rowena A. Bull, Alastair G. Stewart, Philip M. Hansbro, Daniel Christ
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Here, Rouet et al. present a strategy for the identification of broadly neutralising antibodies against SARS-CoV-2 receptor binding domain from peripheral blood mononuclear cells of convalescent patients, which enabled the identification of a new cla
Externí odkaz:
https://doaj.org/article/d7c35bcc59bc4a9fb845343c96f9aa30
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
To achieve longevity, IgA plasma cells require a sophisticated anatomical microenvironment that provides cytokines, cell-cell contacts, and nutrients as well as metabolites. The intestinal epithelium harbors cells with distinct functions and represen
Externí odkaz:
https://doaj.org/article/602d1c30215d4345b2f317c1b3b979d1
Autor:
Louisa Ruhl, Isabell Pink, Jenny F. Kühne, Kerstin Beushausen, Jana Keil, Stella Christoph, Andrea Sauer, Lennart Boblitz, Julius Schmidt, Sascha David, Hans-Martin Jäck, Edith Roth, Markus Cornberg, Thomas F. Schulz, Tobias Welte, Marius M. Höper, Christine S. Falk
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-15 (2021)
Abstract The systemic processes involved in the manifestation of life-threatening COVID-19 and in disease recovery are still incompletely understood, despite investigations focusing on the dysregulation of immune responses after SARS-CoV-2 infection.
Externí odkaz:
https://doaj.org/article/292d99a4599e43ee926ae09f6d8a68b0