Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hans-Ludwig Schaefer"'
Autor:
Thomas Kopf, Hans-Ludwig Schaefer, Martin Troetzmueller, Harald Koefeler, Mark Broenstrup, Tatiana Konovalova, Gerd Schmitz
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106849 (2014)
Fenofibrate (FF) lowers plasma triglycerides via PPARα activation. Here, we analyzed lipidomic changes upon FF treatment of fructose fed rats. Three groups with 6 animals each were defined as control, fructose-fed and fructose-fed/FF treated. Male W
Externí odkaz:
https://doaj.org/article/dce91b03ad8b49c191c7cf76acc8a99d
Autor:
Marc D. Voss, Alexander Schiffer, Stefan Petry, Christine Rudolph, Hans-Ludwig Schaefer, Thomas Langer, Werngard Czechtizky, Ziyu Li, Harm Brummerhop
Publikováno v:
Biochemical and Biophysical Research Communications. 449:327-331
Phosphatidylinositol-5-phosphate 4-kinase, type II, beta (PIP5K2B) is linked to the pathogenesis of obesity, insulin resistance and diabetes. Here, we describe the identification of a novel pyrimidine-2,4-diamine PIP5K2B inhibitor, designated SAR088.
Autor:
Martin Gerl, Gabriele Biemer-Daub, Hans-Ludwig Schaefer, Johanna Kuhlmann, Werner Kramer, Ulrich Belz, Hans-Paul Juretschke, Marion Stein, Anja Beha, Manfred Quint, Claudia Neumann-Haefelin, Andreas W. Herling, Elke Kleinschmidt, Dieter Schmoll, Mark Broenstrup
Publikováno v:
Diabetes. 53(3)
The physiological dynamics of intramyocellular lipids (IMCLs) in different muscle types and of hepatocellular lipids (HepCLs) are still uncertain. The dynamics of IMCLs in the soleus, tibialis anterior, and extensor digitorum longus (EDL) muscles and
Autor:
Burger Hans-Joerg, Werner Kramer, Hans-Ludwig Schaefer, Gerrit Schubert, Andreas W. Herling, Horst Hemmerle
Publikováno v:
European journal of pharmacology. 386(1)
S 4048 (1-[2-(4-Chloro-phenyl)-cyclopropylmethoxy]-3, 4-dihydroxy-5-(3-imidazo[4, 5-b]pyridin-1-yl-3-phenyl-acryloyloxy)-cyclohexanecarboxylic acid), a derivative of chlorogenic acid, specifically inhibits the glucose-6-phosphate translocating compon