Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Hans-Jurgen Wester"'
Autor:
Hans-Jurgen Wester, Heinz Hofler, Markus Schwaiger, Michael A. Cahill, Andre Schrattenholz, Ken Herrmann, Maria Burian, Florian Lordick, Karen Becker, Katja Specht, Katja Ott, Rupert Langer
Supplementary Data from Protein Expression Profiling in Esophageal Adenocarcinoma Patients Indicates Association of Heat-Shock Protein 27 Expression and Chemotherapy Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0edbcbe277eb4e2d05b8b3986493a0
https://doi.org/10.1158/1078-0432.22439739
https://doi.org/10.1158/1078-0432.22439739
Autor:
Hans-Jurgen Wester, Heinz Hofler, Markus Schwaiger, Michael A. Cahill, Andre Schrattenholz, Ken Herrmann, Maria Burian, Florian Lordick, Karen Becker, Katja Specht, Katja Ott, Rupert Langer
Purpose: To identify pretherapeutic predictive biomarkers in tumor biopsies of patients with locally advanced esophageal adenocarcinomas treated with neoadjuvant chemotherapy, we used an explorative proteomic approach to correlate pretherapeutic prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9431caca7721efb88230208c02126ec
https://doi.org/10.1158/1078-0432.c.6517164.v1
https://doi.org/10.1158/1078-0432.c.6517164.v1
Autor:
Nadine Holzleitner, Sebastian Fischer, Isabel Maniyankerikalam, Roswitha Beck, Constantin Lapa, Hans-Jürgen Wester, Thomas Günther
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background We recently introduced radiohybrid (rh)-based minigastrin analogs e.g., DOTA-rhCCK-18 (DOTA-D-Dap(p-SiFA)-(D-γ-Glu)8-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH2), that revealed substantially increased activity retention in the tumor. However
Externí odkaz:
https://doaj.org/article/793c094f567543f6a4050d4c4b105f85
Autor:
Alexander Wurzer, Francesco De Rose, Sebastian Fischer, Markus Schwaiger, Wolfgang Weber, Stephan Nekolla, Hans-Jürgen Wester, Matthias Eiber, Calogero D’Alessandria
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-14 (2024)
Abstract Background Radiohybrid PSMA-targeted ligands (rhPSMA) have been introduced as a novel platform for theranostic applications. Among a variety of rhPSMA-ligands developed for radioligand therapy, two stereoisomers [177Lu]Lu-rhPSMA-10.1 and -10
Externí odkaz:
https://doaj.org/article/ccf30793e8eb4523920eb4bb36e6f0e6
Autor:
Hui Wang, Marianne Remke, Thomas Horn, Kristina Schwamborn, Yiyao Chen, Katja Steiger, Wilko Weichert, Hans-Jürgen Wester, Margret Schottelius, Wolfgang A. Weber, Matthias Eiber
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Background Targeting prostate-specific membrane antigen (PSMA) has been highly successful for imaging and treatment of prostate cancer. However, heterogeneity in immunohistochemistry indicates limitations in the effect of imaging and radionu
Externí odkaz:
https://doaj.org/article/e730479a683c4bf18070e7f31822ee14
Autor:
Timo Grimmer, Hans-Jurgen Wester, Igor Yakushev, B Hooshyar Yousefi, Stefan Förster, Alexander Drzezga, Kuangyu Shi, M. Schwaiger
Publikováno v:
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin.
Autor:
Hans-Jurgen Wester, B Hooshyar Yousefi, M. Schwaiger, Kuangyu Shi, Wolfgang A. Weber, Igor Yakushev, Thomas Arzberger
Publikováno v:
57. Jahrestagung der Deutschen Gesellschaft für Nuklearmedizin.
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Background Over the last years, several strategies have been reported to improve the metabolic stability of minigastrin analogs. However, currently applied compounds still reveal limited in vitro and in vivo stability. We thus performed a gl
Externí odkaz:
https://doaj.org/article/b2cf2f4f6b9c494c9c68d658fa804ed7
Publikováno v:
Results in Chemistry, Vol 6, Iss , Pp 101076- (2023)
A method for the introduction of bifunctionalized 1,4,7,10-tetraazacyclododecane-N,N’,N’’,N’’’-tetraacetic acid (DOTA) into the bridging unit of peptide-based radiopharmaceuticals has been developed. The method is executed in the context
Externí odkaz:
https://doaj.org/article/14bbec5ebe624e79b8bdbc8d04dc33b5
Autor:
Alex J, Poot, Kevin W A, Adamzek, Albert D, Windhorst, Maria J W D, Vosjan, Saskia, Kropf, Hans-Jurgen, Wester, Guus A M S, van Dongen, Danielle J, Vugts
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 60(5)
Dozens of monoclonal antibodies (mAbs) have been approved for clinical use, and hundreds more are under development. To support these developments and facilitate a personalized medicine approach, PET imaging and quantification of mAbs, after chelatio