Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Hans-Joachim Merker"'
Publikováno v:
Micron. 38:572-579
By routine applied quantitative BAL methods are particularly helpful for the diagnosis of pulmonary sarcoidosis. Here the morphology of the alveolar cells does not play a role. However, morphological and especially electron microscopic investigations
Autor:
Olaf Burkhardt, Hans-Joachim Merker
Publikováno v:
Annals of Anatomy - Anatomischer Anzeiger. 184:55-60
Lymphocytes of human blood were isolated by Ficoll gradients and separated into a CD8 positive fraction using the "Immunobead Technique". Electron microscopic examination approximately 45 min after mixing with the beads at room temperature revealed a
Autor:
Olaf Burkhardt, Hans-Joachim Merker
Publikováno v:
Annals of Anatomy - Anatomischer Anzeiger. 184:45-53
Lymphocytes were isolated from the blood of healthy juvenile test persons by the FICOLL method. Subsequently, CD4-, CD8-, and CD19-positive cells were obtained by the use of magnetic beads. The sandwich technique and gold labelling method (preembeddi
Autor:
Peter Kossmehl, Roland Lauster, Sara-Joan Pinto-Sietsma, Hans-Joachim Merker, Svenja Sethmann, Yigal M. Pinto, Sonja Engler, Martin Paul, Berthold Hocher, Tobias Philipp, Heike Marquardt
Publikováno v:
Hypertension, 36(5), 747-754. Lippincott Williams and Wilkins
Hypertension, 36(5), 747-754. LIPPINCOTT WILLIAMS & WILKINS
Hypertension, 36(5), 747-754. LIPPINCOTT WILLIAMS & WILKINS
Abstract —Angiotensin II recruits transforming growth factor β 1 (TGFβ 1 ) and is related to left ventricular fibrosis. However, it is unclear whether chronic in vivo reduction in left ventricular TGFβ 1 expression blunts fibrosis and improves o
Publikováno v:
Biochemical Journal. 342:615-623
We have examined the mechanism by which collagen-binding integrins co-operate with insulin-like growth factor-I (IGF-I) receptors (IGF-IR) to regulate chondrocyte phenotype and differentiation. Adhesion of chondrocytes to anti-β1 integrin antibodies
Autor:
Hans-Joachim Merker, Mehdi Shakibaei
Publikováno v:
Cell and Tissue Research. 296:565-573
Integrins are cell-surface receptors that mediate cell attachment to extracellular matrix components. The pericellular matrix in cartilage not only is a mechanical framework, but is also important for chondrocyte differentiation and stabilization of
Since the thalidomide (Contergan) tragedy about 30 years ago the induction of prenatally-induced morphological or functional defects has been an area of extensive research. Risk assessment of prenatally-induced adverse health effects is still a diffi
Publikováno v:
Annals of Anatomy - Anatomischer Anzeiger. 180:223-235
Summary The common carotid arteries of normal adult rats were investigated electron-microscopically after tannic acid fixation. This fixation technique yields a better demonstrability of the structures of the connective tissue, the basal laminae and
Publikováno v:
Annals of Anatomy - Anatomischer Anzeiger. 179:137-147
Direct sprouting (angiogenesis) does not occur during the formation of capillary-like tubes in an aorta/ collagen gel in the in vitro model. However, emigration of cells which stretch, arrange themselves side by side, form contacts (unspecific, tight
Publikováno v:
Human & Experimental Toxicology. 16:146-153
1 Reproductive toxicity and toxicokinetics of lindane during lactation were studied. For the reproductive toxicity study the dams were treated with a single dose of 6 mg/kg on day 9 or 14 of lactation, or with 1 mg/kg on days 9 to 14 of lactation. Th