Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hans-Joachim Gabiu"'
Autor:
Lareno L. Villones, Anna-Kristin Ludwig, Hiroyuki Kumeta, Seiya Kikuchi, Rika Ochi, Tomoyasu Aizawa, Shin-Ichiro Nishimura, Hans-Joachim Gabius, Hiroshi Hinou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Dystroglycan (DG), which constitutes a part of the dystrophin–glycoprotein complex, connects the extracellular matrix to the cytoskeleton. The matriglycans presented by the extracellular α-DG serve as a contact point with extracellular ma
Externí odkaz:
https://doaj.org/article/3b313ae12f4c4ebbae078d91bb584ce4
Autor:
Anneke Miedema, Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina Peferoen-Baert, Anna T. E. Pijnacker, Evelyn M. Wesseling, Marion H. C. Wijering, Hans-Joachim Gabius, Sandra Amor, Bart J. L. Eggen, Susanne M. Kooistra
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-18 (2022)
Abstract Multiple sclerosis (MS) is a disease of the central nervous system that is characterized by inflammation and focal areas of demyelination, ultimately resulting in axonal degradation and neuronal loss. Several lines of evidence point towards
Externí odkaz:
https://doaj.org/article/e6a6235939ee4b9089024f9f8ef305b6
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101116- (2021)
Background: Even though members of the family of adhesion/growth-regulatory galectins are increasingly detected to be co-expressed, they are still being routinely tested separately. The recent discovery of heterodimer formation among galectins-1, -3,
Externí odkaz:
https://doaj.org/article/4fc2bda2ad644348b6e9c750779b8b8c
Autor:
Paul V. Murphy, Antonio Romero, Qi Xiao, Anna-Kristin Ludwig, Srinivas Jogula, Nadezhda V. Shilova, Tanuja Singh, Adele Gabba, Bilal Javed, Dapeng Zhang, Francisco J. Medrano, Herbert Kaltner, Jürgen Kopitz, Nicolai V. Bovin, Albert M. Wu, Michael L. Klein, Virgil Percec, Hans-Joachim Gabius
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101919- (2021)
Summary: The small 3-O-sulfated galactose head group of sulfatides, an abundant glycosphingolipid class, poses the (sphinx-like) riddle on involvement of glycan bridging by tissue lectins (sugar code). First, synthesis of head group derivatives for f
Externí odkaz:
https://doaj.org/article/a0046aeb444a470d8b22c9dce74afb36
Autor:
Andrea Flores-Ibarra, Sabine Vértesy, Francisco J. Medrano, Hans-Joachim Gabius, Antonio Romero
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Among members of the family of adhesion/growth-regulatory galectins, galectin-3 (Gal-3) bears a unique modular architecture. A N-terminal tail (NT) consisting of the N-terminal segment (NTS) and nine collagen-like repeats is linked to the ca
Externí odkaz:
https://doaj.org/article/2c7acd4b69ae4cc98caad13f41be21b1
Autor:
Federico M. Ruiz, Francisco J. Medrano, Anna-Kristin Ludwig, Herbert Kaltner, Nadezhda V. Shilova, Nicolai V. Bovin, Hans-Joachim Gabius, Antonio Romero
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1854 (2021)
Galectins are multi-purpose effectors acting via interactions with distinct counterreceptors based on protein-glycan/protein recognition. These processes are emerging to involve several regions on the protein so that the availability of a detailed st
Externí odkaz:
https://doaj.org/article/29179773c8434d8f8b374cf9022f9da3
Autor:
Qi Xiao, Zhichun Wang, Dewight Williams, Pawaret Leowanawat, Mihai Peterca, Samuel E. Sherman, Shaodong Zhang, Daniel A. Hammer, Paul A. Heiney, Steven R. King, David M. Markovitz, Sabine André, Hans-Joachim Gabius, Michael L. Klein, Virgil Percec
Publikováno v:
ACS Central Science, Vol 2, Iss 12, Pp 943-953 (2016)
Externí odkaz:
https://doaj.org/article/3009908fbc0743e6ac8d56ab3c0ce45c
Autor:
João P. Ribeiro, Tammo Diercks, Jesús Jiménez-Barbero, Sabine André, Hans-Joachim Gabius, Francisco Javier Cañada
Publikováno v:
Biomolecules, Vol 5, Iss 4, Pp 3177-3192 (2015)
The characterization of the binding of reducing carbohydrates present as mixtures of anomers in solution to a sugar recepor (lectin) poses severe difficulties. In this situation, NMR spectroscopy enables the observation of signals for each anomer in
Externí odkaz:
https://doaj.org/article/bee0c40d74e740d1b80fbc3959049bf8
Publikováno v:
Molecules, Vol 20, Iss 2, Pp 1788-1823 (2015)
The view on the significance of the presence of glycans in glycoconjugates is undergoing a paradigmatic change. Initially mostly considered to be rather inert and passive, the concept of the sugar code identifies glycans as highly versatile platform
Externí odkaz:
https://doaj.org/article/9f23d8b63cde495f96979b2e1dec31ee
Publikováno v:
Molecules, Vol 18, Iss 4, Pp 4026-4053 (2013)
Coding of biological information is not confined to nucleic acids and proteins. Endowed with the highest level of structural versatility among biomolecules, the glycan chains of cellular glycoconjugates are well-suited to generate molecular messages/
Externí odkaz:
https://doaj.org/article/e4fed963d1364fbcaf01463338fe7bac