Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Hans-Jürgen Pietzsch"'
Autor:
Franziska Striese, Christin Neuber, Sandy Gräßel, Claudia Arndt, Martin Ullrich, Jörg Steinbach, Jens Pietzsch, Ralf Bergmann, Hans-Jürgen Pietzsch, Wiebke Sihver, Marcus Frenz, Anja Feldmann, Michael P. Bachmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9420 (2023)
Prostate specific membrane antigen (PSMA) is an excellent target for imaging and treatment of prostate carcinoma (PCa). Unfortunately, not all PCa cells express PSMA. Therefore, alternative theranostic targets are required. The membrane protein prost
Externí odkaz:
https://doaj.org/article/f1f82be2f6d34d6085c004a44449232e
Autor:
Santiago Andrés Brühlmann, Martin Walther, Martin Kreller, Falco Reissig, Hans-Jürgen Pietzsch, Torsten Kniess, Klaus Kopka
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 314 (2023)
Theranostic matched pairs of radionuclides have aroused interest during the last couple of years, and in that sense, copper is one element that has a lot to offer, and although 61Cu and 64Cu are slowly being established as diagnostic radionuclides fo
Externí odkaz:
https://doaj.org/article/81e626fb223d4ae986ac978a77c95224
Autor:
Andreas Heerwig, Alfred Kick, Paul Sommerfeld, Sophia Eimermacher, Frederick Hartung, Markus Laube, Dietmar Fischer, Hans-Jürgen Pietzsch, Jens Pietzsch, Reik Löser, Michael Mertig, Markus Pietsch, Robert Wodtke
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1650 (2023)
In addition to the classic functions of proteins, such as acting as a biocatalyst or binding partner, the conformational states of proteins and their remodeling upon stimulation need to be considered. A prominent example of a protein that undergoes c
Externí odkaz:
https://doaj.org/article/f9e5b111a7044fb98321b290584126db
Autor:
Santiago Andrés Brühlmann, Martin Kreller, Hans-Jürgen Pietzsch, Klaus Kopka, Constantin Mamat, Martin Walther, Falco Reissig
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1167 (2022)
Targeted Alpha Therapy is a research field of highest interest in specialized radionuclide therapy. Over the last decades, several alpha-emitting radionuclides have entered and left research topics towards their clinical translation. Especially, 225A
Externí odkaz:
https://doaj.org/article/e1bd40fef1c94cd9bfea8361bca86f00
Autor:
Treewut Rassamegevanon, Louis Feindt, Lydia Koi, Johannes Müller, Robert Freudenberg, Steffen Löck, Wiebke Sihver, Enes Çevik, Ariane Christel Kühn, Cläre von Neubeck, Annett Linge, Hans-Jürgen Pietzsch, Jörg Kotzerke, Michael Baumann, Mechthild Krause, Antje Dietrich
Publikováno v:
Cancers, Vol 13, Iss 22, p 5595 (2021)
Combination treatment of molecular targeted and external radiotherapy is a promising strategy and was shown to improve local tumor control in a HNSCC xenograft model. To enhance the therapeutic value of this approach, this study investigated the unde
Externí odkaz:
https://doaj.org/article/25dba7d79733444bab324fa7b79bf155
Autor:
Falco Reissig, David Bauer, Kristof Zarschler, Zbynek Novy, Katerina Bendova, Marie-Charlotte Ludik, Klaus Kopka, Hans-Jürgen Pietzsch, Milos Petrik, Constantin Mamat
Publikováno v:
Cancers, Vol 13, Iss 8, p 1974 (2021)
Currently, targeted alpha therapy is one of the most investigated topics in radiopharmaceutical cancer management. Especially, the alpha emitter 225Ac has excellent nuclear properties and is gaining increasing popularity for the treatment of various
Externí odkaz:
https://doaj.org/article/2c7382675f2e427390ef558d2dc42504
Autor:
Falco Reissig, David Bauer, Martin Ullrich, Martin Kreller, Jens Pietzsch, Constantin Mamat, Klaus Kopka, Hans-Jürgen Pietzsch, Martin Walther
Publikováno v:
Pharmaceuticals, Vol 13, Iss 10, p 272 (2020)
Barium-131 is a single photon emission computed tomography (SPECT)-compatible radionuclide for nuclear medicine and a promising diagnostic match for radium-223/-224. Herein, we report on the sufficient production route 133Cs(p,3n)131Ba by using 27.5
Externí odkaz:
https://doaj.org/article/d47137eec1fc4101b331b6b8c56d1e9f
Autor:
Susann Albert, Claudia Arndt, Anja Feldmann, Ralf Bergmann, Dominik Bachmann, Stefanie Koristka, Florian Ludwig, Pauline Ziller-Walter, Alexandra Kegler, Sebastian Gärtner, Marc Schmitz, Armin Ehninger, Marc Cartellieri, Gerhard Ehninger, Hans-Jürgen Pietzsch, Jens Pietzsch, Jörg Steinbach, Michael Bachmann
Publikováno v:
OncoImmunology, Vol 6, Iss 4 (2017)
Recent treatments of leukemias with chimeric antigen receptor (CAR) expressing T cells underline their impressive therapeutic potential. However, once adoptively transferred into patients, there is little scope left to shut them down after eliminatio
Externí odkaz:
https://doaj.org/article/440020276eed4d92a1364ec457dac05b
Autor:
Wiebke Sihver, Jens Pietzsch, Mechthild Krause, Michael Baumann, Jörg Steinbach, Hans-Jürgen Pietzsch
Publikováno v:
Pharmaceuticals, Vol 7, Iss 3, Pp 311-338 (2014)
The epidermal growth factor receptor (EGFR) has evolved over years into a main molecular target for the treatment of different cancer entities. In this regard, the anti-EGFR antibody cetuximab has been approved alone or in combination with: (a) chemo
Externí odkaz:
https://doaj.org/article/811e2bf1eabe4247b3131cadf7bfad32
Publikováno v:
Molecules, Vol 16, Iss 6, Pp 5228-5240 (2011)
Two basic and simple synthetic routes for mono- and bis-maleimide bearing 1,4,7-triazacyclononane-N,N’,N’’-triacetic acid (NOTA) chelators as new bifunctional chelators are described. The syntheses are characterized by their simplicity and shor
Externí odkaz:
https://doaj.org/article/d6d2f2775e104ea48fd0a22b99d67664