Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Hans-Jörg Habisch"'
Publikováno v:
British Journal of Cancer
Background: Pancreatic stellate cells (PSCs) promote metastasis as well as local growth of pancreatic cancer. However, the factors mediating the effect of PSCs on pancreatic cancer cells have not been clearly identified. Methods: We used a modified B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f8d2e9d36ada7203088220c84b6e952
https://doi.org/10.1038/bjc.2013.706
https://doi.org/10.1038/bjc.2013.706
Publikováno v:
Cancers
Cancers, Vol 2, Iss 3, Pp 1661-1682 (2010)
Cancers, Vol 2, Iss 3, Pp 1661-1682 (2010)
Pancreatic cancer is characterized by its late detection, aggressive growth, intense infiltration into adjacent tissue, early metastasis, resistance to chemo- and radiotherapy and a strong “desmoplastic reaction”. The dense stroma surrounding car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878fb4b5982a4424ddf5d2c0b19fe843
http://europepmc.org/articles/PMC3837330
http://europepmc.org/articles/PMC3837330
Autor:
Rolf E. Brenner, Monika Ehrhart-Bornstein, Stefan Fickert, Vladimir Vukicevic, Andreas Hermann, Catrin List, Peter Bernstein, Alexander Storch, Hans-Jörg Habisch
Publikováno v:
Cytotherapy. 12:17-30
Human adult bone marrow (BM)-derived mesenchymal stromal cells (hMSC) are reported to break germ layer commitment and differentiate into cells expressing neuroectodermal properties. Although it is of pivotal interest for cell replacement therapies fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d095a4f5caabeec9151b8ea2dfcf97d
https://doi.org/10.3109/14653240903313941
https://doi.org/10.3109/14653240903313941
Publikováno v:
Cytotherapy. 10:824-833
Bone marrow (BM)-derived mesenchymal stromal cells (MSC) are promising candidate cells for the development of neuroregenerative therapies. We have previously introduced the pro-neural conversion of human MSC to neural stem cell-like cells (m-NSC) by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c5780053ce2185ac45b76b69ba35ba
https://doi.org/10.1080/14653240802474331
https://doi.org/10.1080/14653240802474331
Autor:
Magdalena Kuzma-Kozakiewicz, Hans Jörg Habisch, Aleksandra Habich, Miroslaw Janowski, Barbara Lukomska, Albert C. Ludolph, Alexander Storch, Krystyna Domanska-Janik, Donat Binder
Publikováno v:
Neuroscience Letters. 430:169-174
The access of transplanted cells to large areas of the CNS is of critical value for cell therapy of chronic diseases associated with widespread neurodegeneration. Intrathecal cell application can match this requirement. Here we describe an efficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90397796485311b4128c06b6b8af5873
https://doi.org/10.1016/j.neulet.2007.10.050
https://doi.org/10.1016/j.neulet.2007.10.050
Autor:
Hans-Jörg Habisch, Regina Gastl, Jörg Fiedler, Stefan Liebau, Stefan Fickert, Johannes Schwarz, Andreas Hermann, Alexander Storch, Rolf E. Brenner
Publikováno v:
Journal of Neuroscience Research. 83:1502-1514
Human adult bone marrow-derived mesodermal stromal cells (hMSCs) are able to differentiate into multiple mesodermal tissues, including bone and cartilage. There is evidence that these cells are able to break germ layer commitment and differentiate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ddd2258a2a4f2a6b964de1adf6a070
https://doi.org/10.1002/jnr.20840
https://doi.org/10.1002/jnr.20840
Autor:
Kurt Schmidt, John Parkinson, Haiying Liang, Antonius C.F. Gorren, Richard C. Venema, Hans jörg Habisch, Bernd Mayer
Publikováno v:
Molecular Pharmacology. 63:682-689
A recombinant adenovirus containing the cDNA of human neuronal nitric-oxide synthase (nNOS) was constructed to characterize the interaction of nNOS with N-[(1,3-benzodioxol-5-yl)methyl]-1-[2-(1H-imidazole-1-yl)pyrimidin-4-yl]-4-(methoxycarbonyl)-pipe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c57db0a148d0c8241a5825c287c7d6
https://doi.org/10.1124/mol.63.3.682
https://doi.org/10.1124/mol.63.3.682
Autor:
Bernd Mayer, Ernst R. Werner, Laura Canevari, Hans-Jörg Habisch, Antonius C.F. Gorren, Kurt Schmidt, Gabriele Werner-Felmayer
Publikováno v:
Biochemical Journal. 348:579-583
Tetrahydrobiopterin [(6R)-5,6,7,8-tetrahydro-L-biopterin, H(4)biopterin] is one of several cofactors of nitric oxide synthases (EC 1.14.13.39). Here we compared the action of N(5)-substituted derivatives on recombinant rat neuronal nitric oxide synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::027fe41142e05ac27d339d85f71f5709
https://doi.org/10.1042/bj3480579
https://doi.org/10.1042/bj3480579
Autor:
Antonius C. F. Gorren, Bernd Mayer, Hans jörg Habisch, Ernst R. Werner, Richard C. Venema, Kurt Schmidt, Penelope Andrew, Regina Golser, Andrea Leber
Publikováno v:
Journal of Biological Chemistry. 275:5291-5296
Endothelial nitric-oxide synthase (type III) (eNOS) was reported to form an inhibitory complex with the bradykinin receptor B2 (B2R) from which the enzyme is released in an active form upon receptor activation (Ju, H., Venema, V. J., Marrero, M. B.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c15bd3c161c27b2a7bf27349836b0795
https://doi.org/10.1074/jbc.275.8.5291
https://doi.org/10.1074/jbc.275.8.5291
Autor:
Hans-Jörg Habisch, Eva Pitters, Christoph Riethmüller, Benjamin Hemmens, Bernd Mayer, Simon J.R. Heales, Kurt Schmidt, Antonius C.F. Gorren, Ernst R. Werner
Publikováno v:
Journal of Biological Chemistry. 274:16047-16051
Tetrahydrobiopterin ((6R)-5,6,7,8-tetrahydro-l-biopterin (H4biopterin)) is an essential cofactor of nitric-oxide synthases (NOSs), but its role in enzyme function is not known. Binding of the pterin affects the electronic structure of the prosthetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54e4023014db19876003c42f9c649a4f
https://doi.org/10.1074/jbc.274.23.16047
https://doi.org/10.1074/jbc.274.23.16047