Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hans-Jörg Frasch"'
Publikováno v:
Microbiology-Reading, 163(7), 1030-1041. AMER SOC MICROBIOLOGY
Polyfructans are synthesized from sucrose by plants (mostly inulin) and by both Gram-negative and Gram-positive bacteria (mostly levan). In the phylum Actinobacteria only levan synthesis by Actinomyces species has been reported. We have identified a
Publikováno v:
Current Opinion in Biotechnology, 24(6), 1144-1150. CURRENT BIOLOGY LTD
Synthetic biology is revolutionizing the way in which the biosphere is explored for natural products. Through computational genome mining, thousands of biosynthetic gene clusters are being identified in microbial genomes, which constitute a rich sour
Autor:
Waldemar Vollmer, Stephan Hüttel, Evi Stegmann, Marlene Röttgen, Anna-Katharina von Thaler, Wolfgang Wohlleben, Hans-Jörg Frasch, Till F. Schäberle, Andreas Kulik
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:4283-4289
The prevailing resistance mechanism against glycopeptides in Gram-positive pathogens involves reprogramming the biosynthesis of peptidoglycan precursors, resulting in d -alanyl- d -lactate depsipeptide termini. Amycolatopsis balhimycina produces the
Publikováno v:
Current opinion in microbiology. 13(5)
Using molecular genetics, biochemistry and organic chemistry the biosynthesis of glycopeptides has been elucidated in detail. It can be categorised in three parts: precursor supply, linking of the peptide backbone and modification reactions. The impo