Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Hans-Jörg Fehling"'
Autor:
Kerstin Schmidt, Qinyu Zhang, Alpaslan Tasdogan, Andreas Petzold, Andreas Dahl, Borros M Arneth, Robert Slany, Hans Jörg Fehling, Andrea Kranz, Adrian Francis Stewart, Konstantinos Anastassiadis
Publikováno v:
eLife, Vol 7 (2018)
Hematopoietic stem cells require MLL1, which is one of six Set1/Trithorax-type histone 3 lysine 4 (H3K4) methyltransferases in mammals and clinically the most important leukemia gene. Here, we add to emerging evidence that all six H3K4 methyltransfer
Externí odkaz:
https://doaj.org/article/255da77bb5e54c95a3ee4ae0a15bcc60
Autor:
Bobby W. S. Li, Ralph Stadhouders, Marjolein J. W. de Bruijn, Melanie Lukkes, Dior M. J. M. Beerens, Maarten D. Brem, Alex KleinJan, Ingrid Bergen, Heleen Vroman, Mirjam Kool, Wilfred F. J. van IJcken, Tata Nageswara Rao, Hans Jörg Fehling, Rudi W. Hendriks
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Group 2 innate lymphoid cells (ILC2) are implicated in allergic asthma as an early innate source of the type 2 cytokines IL-5 and IL-13. However, their induction in house dust mite (HDM)-mediated airway inflammation additionally requires T cell activ
Externí odkaz:
https://doaj.org/article/316d513496904743be80e623bcd5de2e
Autor:
Lars Philipsen, Laura Knop, Andreas Müller, Ute Bank, Hans Jörg Fehling, Ulrich Kalinke, Juliane Mohr, Katrin Deiser, Amelie Witte, Thomas Schüler
Publikováno v:
European journal of immunology
The survival of peripheral T cells is dependent on their access to peripheral lymph nodes (pLNs) and stimulation by Interleukin-7 (IL-7). In pLNs fibroblastic reticular cells (FRCs) and lymphatic endothelial cells (LECs) produce IL-7 suggesting their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4204a564009879c455d5122d5698dbf
https://hdl.handle.net/10033/622180
https://hdl.handle.net/10033/622180
Autor:
Hans Jörg Fehling, Andreas Müller, Ulrich Kalinke, Ute Bank, Juliane Mohr, Thomas Schüler, Amelie Witte, Lars Philipsen, Laura Knop, Katrin Deiser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd8519f7ea7837c7821627447a21052
https://doi.org/10.1002/eji.201948368/v3/response1
https://doi.org/10.1002/eji.201948368/v3/response1
Autor:
Marjolein J. W. de Bruijn, Rudi W. Hendriks, James P. Di Santo, Ralph Stadhouders, Thomas Graf, Ai Ing Lim, Wilfred F. J. van IJcken, Antonio Gomez, Hans Jörg Fehling, Bobby W. S. Li, Tata Nageswara Rao
Publikováno v:
Journal of Allergy and Clinical Immunology, 142(6), 1793-1807. Mosby Inc.
Background Group 2 innate lymphoid cells (ILC2s) are major producers of the cytokines driving allergic asthma, and increased ILC2 numbers have been detected in blood and sputum of asthmatic patients. Asthma susceptibility has a strong genetic compone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4985a7f9ddea0672791c78eef556732e
https://doi.org/10.1016/j.jaci.2017.12.1006
https://doi.org/10.1016/j.jaci.2017.12.1006
Autor:
Francesca Odoardi, Judith Strauss, Markus Reindl, Tanja Litke, Alexander Flügel, Michael Haberl, César Cordero Gómez, Albert Saiz, Fred Lühder, Hans-Jörg Fehling, Anne-Christine Flach, Jürgen Wienands
Publikováno v:
Proceedings of the National Academy of Sciences. 113:3323-3328
Multiple sclerosis (MS) is caused by T cells that are reactive for brain antigens. In experimental autoimmune encephalomyelitis, the animal model for MS, myelin-reactive T cells initiate the autoimmune process when entering the nervous tissue and bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd64dfe04b45f0832544ef54f87ace9
https://doi.org/10.1073/pnas.1519608113
https://doi.org/10.1073/pnas.1519608113
Autor:
Andreas Dahl, Qinyu Zhang, Adrian Francis Stewart, Robert K. Slany, Alpaslan Tasdogan, Konstantinos Anastassiadis, Andreas Petzold, Kerstin Schmidt, Hans Jörg Fehling, Borros M Arneth, Andrea Kranz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3939a83db6bfbcc10faa2b1b0512f29
https://doi.org/10.7554/elife.27157.037
https://doi.org/10.7554/elife.27157.037
Autor:
Adrian Francis Stewart, Konstantinos Anastassiadis, Kerstin Schmidt, Andreas Dahl, Alpaslan Tasdogan, Andreas Petzold, Borros M Arneth, Robert K. Slany, Hans Jörg Fehling, Qinyu Zhang, Andrea Kranz
Publikováno v:
eLife
eLife, Vol 7 (2018)
eLife, Vol 7 (2018)
Hematopoietic stem cells require MLL1, which is one of six Set1/Trithorax-type histone 3 lysine 4 (H3K4) methyltransferases in mammals and clinically the most important leukemia gene. Here, we add to emerging evidence that all six H3K4 methyltransfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35d3be4745554c0fff14f2783ce5a446
https://pubmed.ncbi.nlm.nih.gov/29916805
https://pubmed.ncbi.nlm.nih.gov/29916805
Autor:
Naoko Satoh-Takayama, Hervé Luche, Christian A. J. Vosshenrich, Leila Ben Merzoug, James P. Di Santo, Marcello Albanesi, Solenne Marie, Sarah Lesjean, Hans Jörg Fehling
Publikováno v:
European Journal of Immunology. 44:3380-3391
To study gene functions specifically in NKp46+ cells we developed novel Cre mice allowing for conditional gene targeting in cells expressing Ncr1 (encoding NKp46). We generated transgenic Ncr1greenCre mice carrying an EGFPcre fusion under the control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e67f742554e03f4f5f6861f6f47695d
https://doi.org/10.1002/eji.201444643
https://doi.org/10.1002/eji.201444643
Autor:
Suresh Kumar, Carmen Blum, Hervé Luche, Alpaslan Tasdogan, Hans Reimer Rodewald, Tata Nageswara Rao, Hans Jörg Fehling, Vera C. Martins, Franziska Beckel
Publikováno v:
The Journal of Experimental Medicine
A novel pre-TCRα (pTα) reporter mouse reveals that expression of pTα is confined to the T lineage and does not occur on prethymic progenitors.
Expression of the pre–T cell receptor α (pTα) gene has been exploited in previous studies as a
Expression of the pre–T cell receptor α (pTα) gene has been exploited in previous studies as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be440f1d9469839a68ba087c3d98895
https://doi.org/10.1084/jem.20122609
https://doi.org/10.1084/jem.20122609