Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Hans-Gerhard Burgert"'
Autor:
Andreas Hildenbrand, Precious Cramer, Milena Bertolotti, Nathalie Sophia Kaiser, Kathrin Kläsener, Clara Muriel Nickel, Michael Reth, Albert Heim, Hartmut Hengel, Hans-Gerhard Burgert, Zsolt Ruzsics
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe early transcription unit 3 (E3) of human adenoviruses (HAdVs) encodes several immunoevasins, including the E3/49K protein, which is unique for species D of HAdVs. It is expressed as surface transmembrane protein and shed. E3/49K of HA
Externí odkaz:
https://doaj.org/article/7a5ba3131ec940d5b423370471844f5a
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Recombinant adenovirus (rAd) vectors represent one of the most frequently used vehicles for gene transfer applications in vitro and in vivo. rAd genomes are constructed in Escherichia coli where their genomes can be maintained, propagated, and modifi
Externí odkaz:
https://doaj.org/article/f7efd861407a4a61b8173248defa23bc
Autor:
Vibhu Prasad, Maarit Suomalainen, Yllza Jasiqi, Silvio Hemmi, Patrick Hearing, Louise Hosie, Hans-Gerhard Burgert, Urs F. Greber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Adenovirus (AdV) can cause persistent infections, but underlying mechanisms are poorly understood. Here, Prasad et al. show that the AdV glycoprotein E3-19K activates the unfolded protein response sensor IRE1α, and that this triggers a feedforward l
Externí odkaz:
https://doaj.org/article/0c377f65c8de48bc8b345b4796d48f32
Publikováno v:
Journal of Immunology Research, Vol 2017 (2017)
Externí odkaz:
https://doaj.org/article/24160afaa04840dca2d20ebd7fb6f23c
Publikováno v:
BioTechniques, Vol 22, Iss 5, Pp 868-870 (1997)
Externí odkaz:
https://doaj.org/article/894ff98364fd44aeb93f1ad586cb2008
Publikováno v:
Journal of Virology. 97
The battle between viruses and their hosts is an ongoing arms race. Whereas the host tries to detect and eliminate the virus, the latter counteracts such antiviral measures to replicate and spread.
Autor:
Patrick Hearing, Maarit Suomalainen, Silvio Hemmi, Vibhu Prasad, Yllza Jasiqi, Urs F. Greber, Hans-Gerhard Burgert, Louise Hosie
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Persistent viruses cause chronic disease, and threaten the lives of immunosuppressed individuals. Here, we elucidate a mechanism supporting the persistence of human adenovirus (AdV), a virus that can kill immunosuppressed patients. Cell biological an
Autor:
Stefan Höning, Christina Seed, Keith N. Leppard, Sreenivasan Ponnambalam, Mark Windheim, Larissa Butler, Hans-Gerhard Burgert
Publikováno v:
Journal of Biological Chemistry. 291:6796-6812
The E3 transcription unit of human species C adenoviruses (Ads) encodes immunomodulatory proteins that mediate direct protection of infected cells. Recently, we described a novel immunomodulatory function for E3/49K, an E3 protein uniquely expressed
Autor:
J Southcombe, Elisabeth Kremmer, Christine S. Falk, Harald Renz, Hans-Gerhard Burgert, Janine Mihm, Martina Sester, Doris Urlaub, Mark Windheim, Lucy Chaplin, Kevin M. Dennehy, Carsten Watzl, Maren Claus, Myles Braithwaite
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 110, E4884-E4893 (2013)
The E3 transcription unit of human adenoviruses (Ads) encodes immunomodulatory proteins. Interestingly, the size and composition of the E3 region differs considerably among Ad species, suggesting that distinct sets of immunomodulatory E3 proteins may
Autor:
Heike Ziegler, Hans–Gerhard Burgert, Ulrich H. Koszinowski, Elisabeth Kremmer, Walter Muranyi
Publikováno v:
EMBO J. 19, 870-881 (2000)
Murine cytomegalovirus (MCMV) interferes with the MHC class I pathway of antigen presentation. The type I transmembrane glycoprotein gp40, encoded by the gene m152 , retains major histocompatibility complex (MHC) class I complexes in the endoplasmic