Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Hans-Georg Simon"'
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174563 (2017)
Signaling between the epicardium and underlying myocardium is crucial for proper heart development. The complex molecular interactions and regulatory networks involved in this communication are not well understood. In this study, we integrated mass s
Externí odkaz:
https://doaj.org/article/9aedf4e8a6d04c8188fd72a28b5492ff
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164042 (2016)
Upon vessel injury, platelets become activated and rapidly reorganize their actin cytoskeleton to adhere to the site of endothelial damage, triggering the formation of a fibrin-rich plug to prevent further blood loss. Inactivation of Pdlim7 provides
Externí odkaz:
https://doaj.org/article/dbdb666ab86345d4adda7cad1270c834
Autor:
Jennifer Krcmery, Rajesh Gupta, Rudyard W Sadleir, Molly J Ahrens, Sol Misener, Christine Kamide, Philip Fitchev, Douglas W Losordo, Susan E Crawford, Hans-Georg Simon
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80809 (2013)
The actin-associated protein Pdlim7 is essential for heart and fin development in zebrafish; however, the expression and function of this PDZ-LIM family member in the mammal has remained unclear. Here, we show that Pdlim7 predominantly localizes to a
Externí odkaz:
https://doaj.org/article/34ceea1eba494ea294f5d1f31cb4710e
Autor:
Sarah E Mercer, Chia-Ho Cheng, Donald L Atkinson, Jennifer Krcmery, Claudia E Guzman, David T Kent, Katherine Zukor, Kenneth A Marx, Shannon J Odelberg, Hans-Georg Simon
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52375 (2012)
The inability to functionally repair tissues that are lost as a consequence of disease or injury remains a significant challenge for regenerative medicine. The molecular and cellular processes involved in complete restoration of tissue architecture a
Externí odkaz:
https://doaj.org/article/b76d611a6820446692269f0b08a6b69f
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The spine apparatus is a specialized compartment of the neuronal smooth endoplasmic reticulum (ER) located in a subset of dendritic spines. It consists of stacks of ER cisterns that are interconnected by an unknown dense matrix and are continuous wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d26caa41e4eee41e80e150ccd113e1a
https://doi.org/10.1073/pnas.2203750119
https://doi.org/10.1073/pnas.2203750119
Autor:
Robert W. Dettman, Hans Georg Simon
Publikováno v:
Developmental Dynamics. 247:332-339
The collagen gel has been used to study epithelial-mesenchymal transformation (EMT) for over 30 years. With advances in the field of materials sciences, new options are available to design optically clear, three-dimensional nature-inspired matrix mim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7dc2e0d02cb27eb8850d0f948c52a4a4
https://doi.org/10.1002/dvdy.24560
https://doi.org/10.1002/dvdy.24560
Autor:
Sébastien Tabariès, Logan A. Walsh, Hans Georg Simon, Maude Vinette, Veronique Ouellet, Atilla Omeroglu, Peter M. Siegel, Mireille Dessureault, Yasmina Hachem, Ingrid Hedenfalk, Alexander McNulty, Matthew G. Annis, Siker Kimbung, Brennan Lavoie
Publikováno v:
Genesdevelopment. 33(3-4)
Claudin-2 promotes breast cancer liver metastasis by enabling seeding and early cancer cell survival. We now demonstrate that the PDZ-binding motif of Claudin-2 is necessary for anchorage-independent growth of cancer cells and is required for liver m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c742b22cfbc7281f75445b67296040
https://pubmed.ncbi.nlm.nih.gov/30692208
https://pubmed.ncbi.nlm.nih.gov/30692208
Publikováno v:
Developmental Biology. 382:457-469
Unlike humans, certain adult vertebrates such as newts and zebrafish possess extraordinary abilities to functionally regenerate lost appendages and injured organs, including cardiac muscle. Here, we present new evidence that a remodeled extracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96f5404dc847cd13f986c519872839f3
https://doi.org/10.1016/j.ydbio.2013.08.002
https://doi.org/10.1016/j.ydbio.2013.08.002
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0174563 (2017)
PLoS ONE, Vol 12, Iss 3, p e0174563 (2017)
Signaling between the epicardium and underlying myocardium is crucial for proper heart development. The complex molecular interactions and regulatory networks involved in this communication are not well understood. In this study, we integrated mass s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfc07ded5c95dae2044510c81b5cbe5
https://pubmed.ncbi.nlm.nih.gov/28358917
https://pubmed.ncbi.nlm.nih.gov/28358917
Autor:
Hans Georg Simon, Sarah Calve
Publikováno v:
The FASEB Journal. 26:2538-2545
During forelimb regeneration in the newt Notophthalmus viridescens, the dynamic expression of a transitional matrix rich in hyaluronic acid, tenascin-C, and fibronectin controls muscle cell behavior in vivo and in vitro. However, the influence of ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdfa14be94b0c5ac0f4320d9c94986f
https://doi.org/10.1096/fj.11-200162
https://doi.org/10.1096/fj.11-200162