Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Hans-Dirk Düngen"'
Autor:
Djawid Hashemi, Xuewen Hou, Patrick Doeblin, Jakob Weiß, Rebecca Beyer, Marthe Neye, Jennifer Erley, Paulius Bucius, Radu Tanacli, Titus Kuehne, Marcus Kelm, Moritz Blum, Frank Edelmann, Wolfgang M. Kuebler, Hans-Dirk Düngen, Andreas Schuster, Lukas Stoiber, Sebastian Kelle
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Exercise intolerance is a debilitating symptom in heart failure (HF), adversely affecting both quality of life and long-term prognosis. Emerging evidence suggests that pulmonary artery (PA) compliance may be a contributing factor. This study
Externí odkaz:
https://doaj.org/article/d2d53e4b5e7444b78b939d86956fca78
Autor:
Caroline J. Coats, Ahmad Masri, Michael E. Nassif, Roberto Barriales‐Villa, Michael Arad, Nuno Cardim, Lubna Choudhury, Brian Claggett, Hans‐Dirk Düngen, Pablo Garcia‐Pavia, Albert A. Hagège, James L. Januzzi, Matthew M. Y. Lee, Gregory D. Lewis, Chang‐Sheng Ma, Martin S. Maron, Zi Michael Miao, Michelle Michels, Iacopo Olivotto, Artur Oreziak, Anjali T. Owens, John A. Spertus, Scott D. Solomon, Jacob Tfelt‐Hansen, Marion van Sinttruije, Josef Veselka, Hugh Watkins, Daniel L. Jacoby, Polina German, Stephen B. Heitner, Stuart Kupfer, Justin D. Lutz, Fady I. Malik, Lisa Meng, Amy Wohltman, Theodore P. Abraham
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Aficamten, a novel cardiac myosin inhibitor, reversibly reduces cardiac hypercontractility in obstructive hypertrophic cardiomyopathy. We present a prespecified analysis of the pharmacokinetics, pharmacodynamics, and safety of aficamten in
Externí odkaz:
https://doaj.org/article/ecd7f5b3949f4a8ca276c42cd7292a3f
Autor:
Xuewen Hou, Djawid Hashemi, Jennifer Erley, Marthe Neye, Paulius Bucius, Radu Tanacli, Titus Kühne, Marcus Kelm, Laura Motzkus, Moritz Blum, Frank Edelmann, Wolfgang M. Kuebler, Burkert Pieske, Hans-Dirk Düngen, Andreas Schuster, Lukas Stoiber, Sebastian Kelle
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Heart failure (HF) presents manifestations in both cardiac and vascular abnormalities. Pulmonary hypertension (PH) is prevalent in up 50% of HF patients. While pulmonary arterial hypertension (PAH) is closely associated with pulmonary artery
Externí odkaz:
https://doaj.org/article/ef2ae5a721e34cbca4be2f658c8d2ab4
Autor:
Jovan Veskovic, Mina Cvetkovic, Elvis Tahirovic, Marija Zdravkovic, Svetlana Apostolovic, Dragana Kosevic, Goran Loncar, Danilo Obradovic, Dragan Matic, Aleksandra Ignjatovic, Tatjana Cvetkovic, Maximilian G. Posch, Sara Radenovic, Arsen D. Ristić, Danilo Dokic, Nenad Milošević, Natasa Panic, Hans-Dirk Düngen
Publikováno v:
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Chronic heart failure (CHF) is a severe condition, often co-occurring with depression and anxiety, that strongly affects the quality of life (QoL) in some patients. Conversely, depressive and anxiety symptoms are associated with a
Externí odkaz:
https://doaj.org/article/e898f4781ca242b4ae8e3d6f34552580
Autor:
Michael Boettcher, Gerd Mikus, Dietmar Trenk, Hans‐Dirk Düngen, Frank Donath, Nikos Werner, Mahir Karakas, Nina Besche, Dominik Schulz‐Burck, Mireille Gerrits, James Hung, Corina Becker
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 5, Pp 1204-1214 (2022)
Abstract Vericiguat was developed for the treatment of symptomatic chronic heart failure (HF) in adult patients with reduced ejection fraction who are stabilized after a recent decompensation event. Guidelines recommend long‐acting nitrates, such a
Externí odkaz:
https://doaj.org/article/802eb1a41f814307a5c64af6075f3e09
Autor:
Tobias Daniel Trippel, Meinhard Mende, Hans‐Dirk Düngen, Djawid Hashemi, Johannes Petutschnigg, Kathleen Nolte, Christoph Herrmann‐Lingen, Lutz Binder, Gerd Hasenfuss, Burkert Pieske, Rolf Wachter, Frank Edelmann
Publikováno v:
ESC Heart Failure, Vol 8, Iss 2, Pp 829-841 (2021)
Abstract Aims Galectin‐3 (Gal‐3) predicts long‐term outcome among patients with heart failure (HF) with preserved ejection fraction (HFpEF). The ability of Gal‐3 to diagnose and predict incident HFpEF in a cohort at risk for HFpEF is of parti
Externí odkaz:
https://doaj.org/article/3dedc7953e8b45569391038e17609aff
Autor:
Peter McGranaghan, Anshul Saxena, Hans-Dirk Düngen, Muni Rubens, Sandeep Appunni, Joseph Salami, Emir Veledar, Philipp Lacour, Florian Blaschke, Danilo Obradovic, Goran Loncar, Elvis Tahirovic, Frank Edelmann, Burkert Pieske, Tobias Daniel Trippel
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The cardiac lipid panel (CLP) is a novel panel of metabolomic biomarkers that has previously shown to improve the diagnostic and prognostic value for CHF patients. Several prognostic scores have been developed for cardiovascular disease risk
Externí odkaz:
https://doaj.org/article/a41b0e9c9ddb425f95deab8acb9aae5f
Autor:
Peter McGranaghan, Hans‐Dirk Düngen, Anshul Saxena, Muni Rubens, Joseph Salami, Jasmin Radenkovic, Doris Bach, Svetlana Apostolovic, Goran Loncar, Marija Zdravkovic, Elvis Tahirovic, Jovan Veskovic, Stefan Störk, Emir Veledar, Burkert Pieske, Frank Edelmann, Tobias Daniel Trippel
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 3029-3039 (2020)
Abstract Aims The Cardiac Lipid Panel (CLP) is a newly discovered panel of metabolite‐based biomarkers that has shown to improve the diagnostic value of N terminal pro B type natriuretic peptide (NT‐proBNP). However, little is known about its use
Externí odkaz:
https://doaj.org/article/47cb22b8d6804216abd917e2f079cdec
Autor:
Radu Tanacli, Djawid Hashemi, Marthe Neye, Laura Astrid Motzkus, Moritz Blum, Elvis Tahirovic, Aleksandar Dordevic, Robin Kraft, Seyedeh Mahsa Zamani, Burkert Pieske, Hans‐Dirk Düngen, Sebastian Kelle
Publikováno v:
ESC Heart Failure, Vol 7, Iss 5, Pp 3240-3245 (2020)
Abstract Aims The diagnostic and treatment of patients with heart failure with preserved ejection fraction (HFpEF) are both hampered by an incomplete understanding of the pathophysiology of the disease. Novel imaging tools to adequately identify thes
Externí odkaz:
https://doaj.org/article/d42fb45f7afd4e43bd1afd1621baec6b
Autor:
Djawid Hashemi, Moritz Blum, Meinhard Mende, Stefan Störk, Christiane E. Angermann, Sabine Pankuweit, Elvis Tahirovic, Rolf Wachter, Burkert Pieske, Frank Edelmann, Hans‐Dirk Düngen, the German Competence Network for Heart Failure
Publikováno v:
ESC Heart Failure, Vol 7, Iss 3, Pp 942-952 (2020)
Abstract Aims Whereas syncopal episodes are a frequent complication of cardiovascular disorders, including heart failure (HF), little is known whether syncopes impact the prognosis of patients with HF. We aimed to assess the impact of a history of sy
Externí odkaz:
https://doaj.org/article/494b6b3e95ed4368bd68b35356e87c5a