Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Hans-Dietrich Stachel"'
Autor:
Helmar Görls, Rami A. Abdel-Rahem, Ahmad Q. Daraosheh, Hans-Dietrich Stachel, Hassan Abul-Futouh, Wolfgang Weigand
Publikováno v:
Zeitschrift für anorganische und allgemeine Chemie. 647:931-936
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15a22018f37ba40a2b73e8054dc8f5f3
https://doi.org/10.1002/zaac.202000439
https://doi.org/10.1002/zaac.202000439
Autor:
Christa E. Müller, Hans-Dietrich Stachel, Raghuram Rao Akkinepally, Hermann Poschenrieder, Anke C. Schiedel, Meryem Köse, Alexander Andreas Bauer, Joachim C. Burbiel
Publikováno v:
Bioorganicmedicinal chemistry. 24(21)
Adenosine kinase (AdK) is a key player in controlling intra- and extracellular concentrations of the signaling molecule adenosine. Extensive evidence points to an important role of AdK in several diseases, and suggests that AdK inhibition might be a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228429293e080d845822edbf2d1a9ba0
https://pubmed.ncbi.nlm.nih.gov/27595538
https://pubmed.ncbi.nlm.nih.gov/27595538
Autor:
Hans-Dietrich Stachel, Eduard Eckl, Sabine Jax, Hermann Poschenrieder, Kurt Polborn, Peter Mayer
Publikováno v:
Helvetica Chimica Acta. 89:971-982
Ozonations of alkoxy- and (acyloxy)-substituted alkylidene-lactams 1 and 5 or of the alkylidene-sultams 9 and 10 proceeded by regioselective cleavage of the exocyclic CC bonds (Schemes 1 and 2). These bonds are part of an enamide system and, therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7871377f7abefc398def499f1e1e4256
https://doi.org/10.1002/hlca.200690101
https://doi.org/10.1002/hlca.200690101
Publikováno v:
Liebigs Annalen. 1996:103-107
The synthesis of the hitherto unknown aza analog of ascorbic acid (±)-10a is described. Aldol type reaction of the tetramic acid derivative 4 with tert-butyldimethylsilyloxy acetaldehyde furnished a mixture of the aldol (±)-5b and the diastereomeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a5670f8311cd4605ace7849264ef22e
https://doi.org/10.1002/jlac.199619960116
https://doi.org/10.1002/jlac.199619960116
Autor:
Eduard Eckl, Peter Mayer, Wolfgang Weigand, Barbara Zimmer, Hans-Dietrich Stachel, Ralf Wünsch, Katharina Semmlinger
Publikováno v:
Helvetica Chimica Acta. 88:1208-1220
The 1,2-dithiolosultam derivative 14 was obtained from the (α-bromoalkylidene)propenesultam derivative 9 (Scheme 1). Regioselective cleavage of the two ester groups (1b or 2b) allowed the preparation of derivatives with different substituents at C(3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18659e6c4fbc57408bc66d549d6b90c9
https://doi.org/10.1002/hlca.200590101
https://doi.org/10.1002/hlca.200590101
Publikováno v:
European Journal of Medicinal Chemistry. 40:391-400
A series of oximes, deriving from 2-arylidene-pyrroline-3,4-diones (7, 8, 22, 23) has been prepared. The presence of tautomers in their solutions has been established by spectroscopic means. The compounds reacted with diazomethane chiefly by N-methyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e8219882bd8d25da48b75c7a14d742
https://doi.org/10.1016/j.ejmech.2004.11.010
https://doi.org/10.1016/j.ejmech.2004.11.010
Autor:
Wolfgang Weigand, Hans-Dietrich Stachel, Andreas Windt, Hermann Poschenrieder, Elisabeth Immerz-Winkler, Ralf Wünsch, Norbert Drescher
Publikováno v:
Helvetica Chimica Acta. 86:2471-2480
The title compounds were prepared starting from the dihydropyrrolones 4–6. Nucleophilic displacement and ring closure yielded the 1H-pyrrolo[3,2-c]isothiazol-5(4H)-ones 8 and 10. The fused systems formed salts with strong acids and electrophiles (1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fedd0cab4c2c1a437f626bf9f8dbeb80
https://doi.org/10.1002/hlca.200390200
https://doi.org/10.1002/hlca.200390200
Publikováno v:
Journal of Heterocyclic Chemistry. 40:61-69
Ozonolysis of the pyrrolidinediones 4 afforded the pyrrolidinetriones 5, which in the presence of Lewis acids were converted into maleimide 6. Analogously, ozonolysis of the pyrrolidinones 7 gave the pyrrolidinediones 8, which were converted into the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ad25703ec75a87c45451b8c3967aa4
https://doi.org/10.1002/jhet.5570400108
https://doi.org/10.1002/jhet.5570400108
Autor:
Hans-Dietrich Stachel, Ralf Wünsch, Christian Robl, Stefan Dick, Norbert Drescher, Christine Kreiner, Elisabeth Immerz-Winkler, Wolfgang Weigand, Eduard Eckl
Publikováno v:
Helvetica Chimica Acta. 85:4453-4467
The title compounds were prepared starting from pyrrolinone 4. Nucleophilic-displacement and ring-closure reactions yielded the dithiolopyrrole 5a, which formed salts with electrophiles (7, 8) as well as with bases. The crystal structure of 5a was de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dbfe34939b204d09c8e5083a1e43840
https://doi.org/10.1002/hlca.200290022
https://doi.org/10.1002/hlca.200290022
Publikováno v:
Archiv der Pharmazie. 333:211-216
A series of piperidine-2,3,5-triones (azagrevelfins) has been prepared. A new synthesis has been introduced using the rearrangement of spiroepoxides in the presence of triethyloxonium tetrafluoroborate. The binding affinity toward the N-methyl-D-aspa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::163dda40971608c1f565a5ae443236c8
https://doi.org/10.1002/1521-4184(20007)333:7<211::aid-ardp211>3.0.co
https://doi.org/10.1002/1521-4184(20007)333:7<211::aid-ardp211>3.0.co