Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Hans-Dieter Royer"'
Autor:
Brigitte Royer‐Pokora, Manfred Beier, Artur Brandt, Constanze Duhme, Maike Busch, Carmen deTorres, Hans‐Dieter Royer, Jaume Mora
Publikováno v:
Cancer Medicine, Vol 7, Iss 4, Pp 1359-1368 (2018)
Abstract Wilms tumors (WT) with WT1 mutations do not respond well to preoperative chemotherapy by volume reduction, suggesting resistance to chemotherapy. The histologic pattern of this tumor subtype indicates an intrinsic mesenchymal differentiation
Externí odkaz:
https://doaj.org/article/975b471727b04cac8b1eaaf31c5b25c0
Autor:
Karsten Jürchott, Ralf-Jürgen Kuban, Till Krech, Nils Blüthgen, Ulrike Stein, Wolfgang Walther, Christian Friese, Szymon M Kiełbasa, Ute Ungethüm, Per Lund, Thomas Knösel, Wolfgang Kemmner, Markus Morkel, Johannes Fritzmann, Peter M Schlag, Walter Birchmeier, Tammo Krueger, Silke Sperling, Christine Sers, Hans-Dieter Royer, Hanspeter Herzel, Reinhold Schäfer
Publikováno v:
PLoS Genetics, Vol 6, Iss 12, p e1001231 (2010)
Transcriptional signatures are an indispensible source of correlative information on disease-related molecular alterations on a genome-wide level. Numerous candidate genes involved in disease and in factors of predictive, as well as of prognostic, va
Externí odkaz:
https://doaj.org/article/374dde0b6ad640c3b6dc0984ca6ebe07
Autor:
Hans-Dieter Royer, Carsten Denkert, Brigitte Royer-Pokora, Manfred Dietel, Manfred Beier, Jan Budczies, Matthias U. Kassack, Alexandra Hamacher, Inge Napierski, Sybille Wolf-Kümmeth, Georg von Jonquières, Anne Pölitz, Barbara Hildebrandt, Kati Servan, Niels Eckstein
Supplementary Materials and Methods, Tables 1-4, Figures 1-5 from Hyperactivation of the Insulin-like Growth Factor Receptor I Signaling Pathway Is an Essential Event for Cisplatin Resistance of Ovarian Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eebd652c5403ef4201ff35d78675274
https://doi.org/10.1158/0008-5472.22380036
https://doi.org/10.1158/0008-5472.22380036
Autor:
Sandra E. Dunn, Connie J. Eaves, Hans-Dieter Royer, Isabelle M. Berquin, Pauline Johnson, Afshin Raouf, Anna L. Stratford, Lawrence Lee, Alastair H. Davies, Arezoo Astanehe, Jing Wang, Kaiji Hu, Jennifer H. Law, Kristen M. Reipas, Abbas Fotovati, Karen To
Supplementary Methods and Materials, Figures 1-6 from Y-Box Binding Protein-1 Induces the Expression of CD44 and CD49f Leading to Enhanced Self-Renewal, Mammosphere Growth, and Drug Resistance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d82df214052211b4407e274eea205de
https://doi.org/10.1158/0008-5472.22386402.v1
https://doi.org/10.1158/0008-5472.22386402.v1
Autor:
Hans-Dieter Royer, Carsten Denkert, Brigitte Royer-Pokora, Manfred Dietel, Manfred Beier, Jan Budczies, Matthias U. Kassack, Alexandra Hamacher, Inge Napierski, Sybille Wolf-Kümmeth, Georg von Jonquières, Anne Pölitz, Barbara Hildebrandt, Kati Servan, Niels Eckstein
Platinum plays a central role in the therapy of ovarian cancer, and the emergence of platinum resistance is a major obstacle for clinical management of the disease. We treated A2780 ovarian cancer cells by weekly cycles of cisplatin over a period of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd194349894177406e13d95c1d31a870
https://doi.org/10.1158/0008-5472.c.6499425.v1
https://doi.org/10.1158/0008-5472.c.6499425.v1
Autor:
Constanze Duhme, Jaume Mora, Maike Busch, Hans-Dieter Royer, Carmen de Torres, Brigitte Royer-Pokora, Artur Brandt, Manfred Beier
Publikováno v:
Cancer Medicine
Wilms tumors (WT) with WT1 mutations do not respond well to preoperative chemotherapy by volume reduction, suggesting resistance to chemotherapy. The histologic pattern of this tumor subtype indicates an intrinsic mesenchymal differentiation potentia
Autor:
Hans-Dieter Royer, Nicole Görldt, Brigitte Royer-Pokora, Paul J. Romaniuk, Stefan G. E. Roberts, Maike Busch, Manfred Beier, Artur Brandt, Heinrich Schwindt, Eneda Toska
Publikováno v:
Human Molecular Genetics
The WT1 gene encodes a zinc finger transcription factor important for normal kidney development. WT1 is a suppressor for Wilms tumour development and an oncogene for diverse malignant tumours. We recently established cell lines from primary Wilms tum
Publikováno v:
The Journal of Experimental Medicine
Human T cell clones and a cDNA probe specific for constant regions of the beta subunit of the antigen/major histocompatibility complex (MHC) receptor, TiC beta 1 and TiC beta 2, were employed to determine whether these genes were differentially used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cac0c39538e8c3abd809dc17e00c4e1
https://doi.org/10.1084/jem.160.3.947
https://doi.org/10.1084/jem.160.3.947
Autor:
Ellis L. Reinherz, Oreste Acuto, Marina Fabbi, Hans Dieter Royer, Armand Bensussan, Thomas J. Campen, Claudio Milanese
Recent studies using cloned antigen-specific T lymphocytes and monoclonal antibodies directed at their various surface glycoprotein components have led to the identification of the human T-cell antigen receptor as a surface complex comprised of a clo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::102dfdf89d31209fbe2f7f00521c4080
https://ora.ox.ac.uk/objects/uuid:88a78194-0d44-463b-bfe1-d13e6a59b7db
https://ora.ox.ac.uk/objects/uuid:88a78194-0d44-463b-bfe1-d13e6a59b7db
Autor:
Ekkehard Pomplun, Jürgen Hescheler, Johannes Winkler, Alexander Dellweg, Harald Schicha, Stefan Arnhold, Hans-Dieter Royer, Ralf Kriehuber, F. Sudbrock, Klaus Schomäcker, Matthias Matzkies, Markus Dietlein, Thomas Fischer
Publikováno v:
International Journal of Radiation Biology. 88:961-971
We studied the response of human embryonic stem cells (hESC) to the β-emitter (131)I, which affects the entire cell and to the Auger electron emitter (125)I-deoxyuridine ((125)I-dU), primarily affecting the deoxyribonuleic acid (DNA). The effects we