Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Hans-Dieter Riedel"'
Autor:
Lisa Reinhard, Christian Rupp, Hans-Dieter Riedel, Thomas Ruppert, Thomas Giese, Christa Flechtenmacher, Karl Heinz Weiss, Petra Kloeters-Plachky, Wolfgang Stremmel, Peter Schirmacher, Peter Sauer, Daniel Nils Gotthardt
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29821 (2012)
Background and aimsBile analysis has the potential to serve as a surrogate marker for inflammatory and neoplastic disorders of the biliary epithelium and may provide insight into biliary pathophysiology and possible diagnostic markers. We aimed to id
Externí odkaz:
https://doaj.org/article/4c9a56774a794a25ad324c6ba31a69cb
Autor:
Hasan Kulaksiz, Daniel Rost, Jörg König, Hans-Dieter Riedel, S. Rau, F. Autschbach, Adolf Stiehl, J. F. Riemann
Publikováno v:
European Journal of Clinical Investigation. 38:134-142
Background Cholangiocellular carcinomas and gallbladder carcinomas are highly aggressive tumours with a poor prognosis and are generally regarded as chemoresistant tumours. Overexpression of ATP-binding cassette transporters of the multidrug resistan
Autor:
Kostas Pantopoulos, Bill Andriopoulos, Sebastian Mueller, Julia Mangin, Ulrike Hebling, Hans Dieter Riedel, Jian Wang, Stephan Hegedüsch
Publikováno v:
Journal of Biological Chemistry. 282:20301-20308
Local and systemic inflammatory conditions are characterized by the intracellular deposition of excess iron, which may promote tissue damage via Fenton chemistry. Because the Fenton reactant H(2)O(2) is continuously released by inflammatory cells, a
Autor:
Sven G. Gehrke, U. Hebling, Hans-Dieter Riedel, D. Kieslich, Sebastian Mueller, Wolfgang Stremmel, S. Hegedusch, J. Mangin, K. Pantopoulos
Publikováno v:
Zeitschrift für Gastroenterologie. 41
Autor:
Hasan Kulaksiz, Franziska Theilig, Sebastian Bachmann, Wolfgang Stremmel, Birgit Kallinowski, Hans-Dieter Riedel, Sven G. Gehrke, Uta Merle, Evelyn Fein
Publikováno v:
Histochemistry and Cell Biology. 127:221-226
The newly discovered proteins hemojuvelin (Hjv) and transferrin receptor type 2 (TfR2) are involved in iron metabolism. Mutations in the Hjv and TfR2 gene cause hemochromatosis. We investigated the expression and cellular localization of Hjv and TfR2
Autor:
Hasan Kulaksiz, Sven G. Gehrke, Wolfgang Stremmel, Karin Bents, Iris Kaiser, Uta Merle, Thomas Herrmann, Hans-Dieter Riedel
Publikováno v:
Digestion. 72:25-32
Background/Aims: In HFE-related hereditary hemochromatosis an inappropriately low hepatic expression of the iron-regulatory peptide hepcidin (encoded by HAMP) has been suggested to cause iron overload. The aim of the present study was to evaluate whe
Autor:
Sven G. Gehrke, Birgit Kallinowski, Hans-Dieter Riedel, Inge Mathes, Karin Bents, Wolfgang Stremmel
Publikováno v:
Journal of Molecular Medicine. 81:780-787
Mild iron overload in chronic hepatitis C is associated with liver fibrosis, hepatitis C virus (HCV) genotype 1b infection, and an impaired response to interferon therapy. In this study we evaluated whether polymorphisms in the hemochromatosis gene H
Publikováno v:
Blood Cells, Molecules, and Diseases. 29:459-464
Since its introduction by Neher and Sakmann in 1976 the patch-clamp technique has been extensively used to study processes such as signalling and synaptic transmission, but also for monitoring endo- and exocytosis. Since biological membranes behave l
Autor:
Werner Kramer, Peter Sauer, Petra Klöters-Plachky, Siegfried Stengelin, Hans-Dieter Riedel, Wolfgang Stremmel, Fitscher Ba, Adolf Stiehl, C. Benz
Publikováno v:
Journal of Hepatology. 33:2-8
Accumulation of toxic bile acids in cholestasis contributes to liver injury and depends on their synthesis, secretion and intestinal absorption. In the present study, we investigated the effect of cholestasis on the active ileal absorption of bile ac
Autor:
I. Mohr, Hans-Dieter Riedel, S.G. Gehrke, Wolfgang Stremmel, Karen Brennan, T. Herrmann, Matthias W. Hentze, M.U. Muckenthaler, B.A. Fitscher
Publikováno v:
Blood. 94:3915-3921
Hereditary hemochromatosis (HH) is a common autosomal-recessive disorder of iron metabolism. More than 80% of HH patients are homozygous for a point mutation in a major histocompatibility complex (MHC) class I type protein (HFE), which results in a l