Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hans Wils"'
Autor:
Viacheslav Mylka, Irina Matetovici, Suresh Poovathingal, Jeroen Aerts, Niels Vandamme, Ruth Seurinck, Kevin Verstaen, Gert Hulselmans, Silvie Van den Hoecke, Isabelle Scheyltjens, Kiavash Movahedi, Hans Wils, Joke Reumers, Jeroen Van Houdt, Stein Aerts, Yvan Saeys
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-21 (2022)
Abstract Background Multiplexing of samples in single-cell RNA-seq studies allows a significant reduction of the experimental costs, straightforward identification of doublets, increased cell throughput, and reduction of sample-specific batch effects
Externí odkaz:
https://doaj.org/article/70cb4b7c707e493b8f024717bdd552fa
Autor:
Sara Turcinov, Erik af Klint, Bertrand Van Schoubroeck, Arlette Kouwenhoven, Sohel Mia, Karine Chemin, Hans Wils, Carl Van Hove, An De Bondt, Ken Keustermans, Jeroen Van Houdt, Joke Reumers, Nathan Felix, Navin L. Rao, Pieter Peeters, Frederik Stevenaert, Lars Klareskog, Murray McKinnon, Daniel Baker, Anish Suri, Vivianne Malmström
Publikováno v:
Arthritis & Rheumatology. 75:673-684
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::182d862e41f292d175f2242048da117e
https://doi.org/10.1002/art.42407
https://doi.org/10.1002/art.42407
Autor:
Theresa Schmid, Miray Cetin, Veronica Pinamonti, Ana Mellado Fuentes, Kristina Kromer, Taga Lerner, Jing Zhang, Tamara Boschert, Yonatan Herzig, Christopher Ehlert, Laura Fisch, Valeriia Dragan, Arlette Kouwenhoven, Bertrand Van Schoubroeck, Hans Wils, Carl Van Hove, Michael Platten, Edward Green, Frederik Stevenaert, Nathan J. Felix, John M. Lindner
Effective, unbiased, high-throughput methods to functionally identify both class II and class I HLA-presented T cell epitopes and their cognate T cell receptors (TCRs) are essential for and prerequisite to diagnostic and therapeutic applications, yet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82919b45ad4a89bdeb0ca5cb007d52b9
https://doi.org/10.1101/2023.05.16.540992
https://doi.org/10.1101/2023.05.16.540992
Autor:
Sara, Turcinov, Erik, Af Klint, Bertrand, Van Schoubroeck, Arlette, Kouwenhoven, Sohel, Mia, Karine, Chemin, Hans, Wils, Carl, Van Hove, An, De Bondt, Ken, Keustermans, Jeroen, Van Houdt, Joke, Reumers, Nathan, Felix, Navin L, Rao, Pieter, Peeters, Frederik, Stevenaert, Lars, Klareskog, Murray, McKinnon, Daniel, Baker, Anish, Suri, Vivianne, Malmström
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
CD4+ T cells are implicated in rheumatoid arthritis (RA) pathology from the strong association between RA and certain HLA-class II gene variants. Here, we studied the synovial T cell receptor (TCR) repertoire, T cell phenotypes and T cell specificiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5dce9d27be90cca7cdd8c971c05515b9
https://pubmed.ncbi.nlm.nih.gov/36409582
https://pubmed.ncbi.nlm.nih.gov/36409582
Autor:
Suresh Poovathingal, Ruth Seurinck, Silvie Van den Hoecke, Stein Aerts, Hans Wils, Gert Hulselmans, Jeroen Aerts, Niels Vandamme, Viacheslav Mylka, Jeroen Van Houdt, Irina Matetovici, Yvan Saeys, Joke Reumers
Multiplexing of samples in single-cell RNA-seq studies allows significant reduction of experimental costs, straightforward identification of doublets, increased cell throughput, and reduction of sample-specific batch effects. Recently published multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b151a83fc1a7dee20b228c2398e19d9f
https://doi.org/10.1101/2020.11.16.384222
https://doi.org/10.1101/2020.11.16.384222
Autor:
Paul Thomson, Petra Vinken, Laurent Leclercq, Dries De Maeyer, Xiaoli Meng, Laila Kafu, An De Bondt, Dean J. Naisbitt, Jan Snoeys, Hans Wils
Publikováno v:
ALLERGY
Background Atabecestat is an orally administered BACE inhibitor developed to treat Alzheimer's disease. Elevations in hepatic enzymes were detected in a number of in trial patients, which resulted in termination of the drug development programme. Imm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89f2c3d9fed4ccd1f4b9bf07611a8bd5
https://pubmed.ncbi.nlm.nih.gov/33150583
https://pubmed.ncbi.nlm.nih.gov/33150583
Publikováno v:
Methods in Molecular Biology ISBN: 9781493985579
Currently one of the few molecules that equally excites a neuroscientist, a cancer biologist, an immunologist, and a developmental biologist is progranulin (GRN/Grn)-a pluripotent growth factor that plays key roles in cell survival, proliferation, de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c692259fd171f148f36640aa9c754934
https://doi.org/10.1007/978-1-4939-8559-3_16
https://doi.org/10.1007/978-1-4939-8559-3_16
Autor:
Hans Wils, Samir Kumar-Singh, Chantal Ceuterick-de Groote, Geert Joris, Ivy Cuijt, Jonathan Janssens, Gernot Kleinberger, Christine Van Broeckhoven
Publikováno v:
Molecular Neurobiology
Molecular neurobiology
Molecular neurobiology
Mutations in TAR DNA-binding protein 43 (TDP-43) are associated with familial forms of amyotrophic lateral sclerosis (ALS), while wild-type TDP-43 is a pathological hallmark of patients with sporadic ALS and frontotemporal lobar degeneration (FTLD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c22960f3d8ca1378a07cead6c88f205e
https://doi.org/10.1007/s12035-013-8427-5
https://doi.org/10.1007/s12035-013-8427-5
Autor:
Peter Ponsaerts, Jean-Pierre Timmermans, Christine Van Broeckhoven, Hans Wils, Gernot Kleinberger, Samir Kumar-Singh, Geert Joris
Publikováno v:
Journal of Neurochemistry. 115:735-747
Null mutations in progranulin (GRN) are associated with frontotemporal lobar degeneration characterized by intraneuronal accumulation of TAR DNA-binding protein-43 (TDP-43). However, the mechanism by which GRN deficiency leads to neurodegeneration re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93946abeb1af23c21b6f2a69509c2a0d
https://doi.org/10.1111/j.1471-4159.2010.06961.x
https://doi.org/10.1111/j.1471-4159.2010.06961.x
Autor:
Samir Kumar-Singh, Christine Van Broeckhoven, Sandra Pereson, Eileen McGowan, Hans Wils, Dieter Deforce, Mado Vandewoestyne, Gernot Kleinberger, Bianca Van Broeck, Geert Joris, Ivy Cuijt, Mike Hutton
Publikováno v:
The Journal of Pathology. 219:173-181
Amyloid-beta (Abeta) plaques are pathological hallmarks of Alzheimer disease (AD). In addition, innate inflammatory responses, such as those mediated by microglia, are integral to the pathogenesis of AD. Interestingly, only dense-core plaques and not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5357375d638c435214ec8a7c60d60c05
https://doi.org/10.1002/path.2580
https://doi.org/10.1002/path.2580