Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Hans Wienk"'
Autor:
Dharjath Shahul Hameed, Gabrielle B. A. van Tilburg, Remco Merkx, Dennis Flierman, Hans Wienk, Farid El Oualid, Kay Hofmann, Rolf Boelens, Huib Ovaa
Publikováno v:
Frontiers in Chemistry, Vol 7 (2020)
Ubiquitination is a process in which a protein is modified by the covalent attachment of the C-terminal carboxylic acid of ubiquitin (Ub) to the ε-amine of lysine or N-terminal methionine residue of a substrate protein or another Ub molecule. Each o
Externí odkaz:
https://doaj.org/article/e816a26af1e746148099c3e686d06b53
Autor:
Nicole J. Bale, Dimitry Y. Sorokin, Ellen C. Hopmans, Michel Koenen, W. Irene C. Rijpstra, Laura Villanueva, Hans Wienk, Jaap S. Sinninghe Damsté
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
We analyzed the polar membrane lipids of 13 strains of halo(alkali)philic euryarchaea from hypersaline lakes. Nine belong to the class Halobacteria, representing two functional groups: aerobic polysaccharide utilizers and sulfur-respiring anaerobes.
Externí odkaz:
https://doaj.org/article/050b71d07e2b4887bac302b8c833501f
Autor:
Alessandro Emendato, Remo Guerrini, Erika Marzola, Hans Wienk, Rolf Boelens, Serena Leone, Delia Picone
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
Endocannabinoid peptides, or “pepcans,” are endogenous ligands of the CB1 cannabinoid receptor. Depending on their length, they display diverse activity: For instance, the nona-peptide Pepcan-9, also known as hemopressin, is a powerful inhibitor
Externí odkaz:
https://doaj.org/article/9f093e91903e43dbad4a62b2a0e41733
Autor:
Michiel L. Bexkens, Verena Zimorski, Maarten J. Sarink, Hans Wienk, Jos F. Brouwers, Johan F. De Jonckheere, William F. Martin, Fred R. Opperdoes, Jaap J. van Hellemond, Aloysius G.M. Tielens
Publikováno v:
Cell Reports, Vol 25, Iss 3, Pp 537-543.e3 (2018)
Summary: Naegleria gruberi is a free-living non-pathogenic amoeboflagellate and relative of Naegleria fowleri, a deadly pathogen causing primary amoebic meningoencephalitis (PAM). A genomic analysis of N. gruberi exists, but physiological evidence fo
Externí odkaz:
https://doaj.org/article/9bd6cd77821c451ca9fb2f16b37bb5e1
Autor:
Frank Schwede, Daniela Bertinetti, Carianne N Langerijs, Michael A Hadders, Hans Wienk, Johanne H Ellenbroek, Eelco J P de Koning, Johannes L Bos, Friedrich W Herberg, Hans-Gottfried Genieser, Richard A J Janssen, Holger Rehmann
Publikováno v:
PLoS Biology, Vol 13, Iss 1, p e1002038 (2015)
The second messenger cAMP is known to augment glucose-induced insulin secretion. However, its downstream targets in pancreatic β-cells have not been unequivocally determined. Therefore, we designed cAMP analogues by a structure-guided approach that
Externí odkaz:
https://doaj.org/article/53ea691117ff4f0aada85ec8fd78efc2
Autor:
David I. Stuart, Eva Pereiro, Harald Schwalbe, Anastassis Perrakis, Susan Daenke, Hans Wienk, Lucia Banci, Manfred S. Weiss
Publikováno v:
Journal of Visualized Experiments
Ahmad, M. U. D. et al. Nano-differential scanning fluorimetry for screening in fragment-based lead discovery. Journal of Visualized Experiments: JoVE. (171), e62469 (2021). Barbieri, L., Luchinat, E. Monitoring protein-ligand interactions in human ce
Autor:
Jeroen Molenaar, Alexander Fish, Sridhar Sreeramulu, Harald Schwalbe, Nadide Altincekic, Misbha Ud Din Ahmad, Christian Richter, Hans Wienk, Anastassis Perrakis
Publikováno v:
Journal of Visualized Experiments
Thermal shift assays (TSAs) examine how the melting temperature (Tm) of a target protein changes in response to changes in its environment (e.g., buffer composition). The utility of TSA, and specifically of nano-Differential Scanning Fluorimetry (nan
Autor:
Poul Nissen, Harald Schwalbe, Dmitri Svergun, David Stuart, Hans Wienk, Hartmut Oschkinat, Rolf Boelens, Jan Ellenberg, Anastassis Perrakis, Margarida Archer, Martin Austin Walsh
Publikováno v:
FEBS Letters
iNEXT Consortium 2018, ' iNEXT : a European facility network to stimulate translational structural biology ', FEBS Letters, vol. 592, no. 12, pp. 1909-1917 . https://doi.org/10.1002/1873-3468.13062
University of Oulu Repository-Jultika
PURE Aarhus University
European Union Open Data Portal
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ORCID
Microsoft Academic Graph
Sygma
NARCIS
iNEXT Consortium 2018, ' iNEXT : a European facility network to stimulate translational structural biology ', FEBS Letters, vol. 592, no. 12, pp. 1909-1917 . https://doi.org/10.1002/1873-3468.13062
University of Oulu Repository-Jultika
PURE Aarhus University
European Union Open Data Portal
UnpayWall
ORCID
Microsoft Academic Graph
Sygma
NARCIS
iNEXT, ‘Infrastructure for NMR, EM and X‐rays for Translational research’, is a EC‐funded Horizon 2020 network of national infrastructures aiming to facilitate EC‐supported, trans‐national user access to several high‐end structural biol
Publikováno v:
Protein Science. 25:1722-1733
Bacterial translation initiation factor IF2 complexed with GTP binds to the 30S ribosomal subunit, promotes ribosomal binding of fMet-tRNA, and favors the joining of the small and large ribosomal subunits yielding a 70S initiation complex ready to en
Publikováno v:
Cells
Volume 8
Issue 12
Volume 8
Issue 12
Signalling by cyclic adenosine monophosphate (cAMP) occurs via various effector proteins, notably protein kinase A and the guanine nucleotide exchange factors Epac1 and Epac2. These proteins are activated by cAMP binding to conserved cyclic nucleotid