Isolating the effect of confounding from the observed survival benefit of screening participants — a methodological approach illustrated by data from the German mammography screening programme

Autor: Laura Buschmann, Ina Wellmann, Nadine Bonberg, Jürgen Wellmann, Hans-Werner Hense, André Karch, Heike Minnerup

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-13 (2024)

Abstract Background Mammography screening programmes (MSP) aim to reduce breast cancer mortality by shifting diagnoses to earlier stages. However, it is difficult to evaluate the effectiveness of current MSP because analyses can only rely on observat

Externí odkaz: https://doaj.org/article/9045ee210bed4e1280f4def852409e91

Incidence of advanced-stage breast cancer in regular participants of a mammography screening program: a prospective register-based study

Autor: Laura Khil, Jan Heidrich, Ina Wellmann, Vanessa Kääb-Sanyal, Stefanie Weigel, Walter Heindel, Hans-Werner Hense, Oliver Heidinger

Publikováno v: BMC Cancer, Vol 20, Iss 1, Pp 1-9 (2020)

Abstract Background The European Guidelines for breast cancer screening suggest that the impact of population-based mammography screening programmes (MSP) may be assessed using the relative reduction in the incidence of advanced breast cancer (ABC, t

Externí odkaz: https://doaj.org/article/ca9807a10e184528baa32b44809b7b8e

Digital breast tomosynthesis plus synthesised mammography versus digital screening mammography for the detection of invasive breast cancer (TOSYMA): a multicentre, open-label, randomised, controlled, superiority trial

Autor: Walter Heindel, Stefanie Weigel, Joachim Gerß, Hans-Werner Hense, Alexander Sommer, Miriam Krischke, Laura Kerschke

Publikováno v: The Lancet Oncology. 23:601-611

Two dimensional (2D) full-field digital mammography is the current standard of breast cancer screening. Digital breast tomosynthesis generates pseudo-three dimensional datasets of the breast from which synthesised 2D (s2D) mammograms can be reconstru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da23662670abbb46668eaff261f3736
https://doi.org/10.1016/s1470-2045(22)00194-2

Genetic Risk, Lifestyle, and Age-Related Macular Degeneration in Europe

Autor: A C C Coolen, Audrey Cougnard-Gregoire, Marius Ueffing, Timo Verzijden, Johanna M. Colijn, Bénédicte M. J. Merle, Hans-Werner Hense, Rufino Silva, Sascha Fauser, Carel B. Hoyng, Catherine Creuzot-Garcher, Caroline C W Klaver, Magda A. Meester-Smoor, Anneke I. den Hollander, Anita de Breuk, Cécile Delcourt

Publikováno v: Ophthalmology. 128:1039-1049

Purpose Age-related macular degeneration (AMD) is a common multifactorial disease in the elderly with a prominent genetic basis. Many risk variants have been identified, but the interpretation remains challenging. We investigated the genetic distribu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff1abdd581b2fed8a4fe481a0f40f255
https://doi.org/10.1016/j.ophtha.2020.11.024

Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: a meta-analysis in Europeans

Autor: Matthias M Mauschitz, Timo Verzijden, Alexander K Schuster, Hisham Elbaz, Norbert Pfeiffer, Anthony Khawaja, Robert N Luben, Paul J Foster, Franziska G Rauscher, Kerstin Wirkner, Toralf Kirsten, Jost B Jonas, Mukharram M Bikbov, Ruth Hogg, Tunde Peto, Audrey Cougnard-Grégoire, Geir Bertelsen, Maja Gran Erke, Fotis Topouzis, Dimitrios A Giannoulis, Caroline Brandl, Iris M Heid, Catherine P Creuzot-Garcher, Pierre-Henry Gabrielle, Hans-Werner Hense, Daniel Pauleikhoff, Patricia Barreto, Rita Coimbra, Stefano Piermarocchi, Vincent Daien, Frank G Holz, Cecile Delcourt, Robert P Finger

Publikováno v: European Eye Epidemiology (E3) Consortium 2022, ' Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: a meta-analysis in Europeans ', British Journal of Ophthalmology . https://doi.org/10.1136/bjo-2022-321985
British Journal of Ophthalmology. BMJ Publishing Group

Background/aimsTo investigate the association of commonly used systemic medications with prevalent age-related macular degeneration (AMD) in the general population.MethodsWe included 38 694 adults from 14 population-based and hospital-based studies f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ba90653013da2e52916b2e80e54c6a
https://pubmed.ncbi.nlm.nih.gov/36344262