Výsledky vyhledávání - "Hans Veit Coester"

Improving the Assessment of Flow-Mediated Dilation Through Detection of Peak Time in Healthy Subjects and Subjects With Type 2 Diabetes

Autor: Theresa Herbrand, Hans J. DeVries, Tim Heise, Malte Kelm, Christian Heiss, Annelie Fischer, Roberto Sansone, Hans-Veit Coester

Publikováno v: Angiology. 72(5)

The assessment of flow-mediated dilation (FMD) is widely used to quantify endothelial function. Historically, FMD was determined at 60 seconds post-cuff deflation. We investigated whether FMD would be more accurate if determined at maximum dilatory p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36918b195014524e0969c79fd4e37f33
https://pubmed.ncbi.nlm.nih.gov/33380161

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Injecting without pressing a button: An exploratory study of a shield‐triggered injection mechanism

Autor: Ole Rasmussen, Hans-Veit Coester, Eric Zijlstra, Leona Plum-Mörschel, Tim Heise, Marianne Qvist, Tord Rikte, Line Kynemund Pedersen, Thomas Sparre

Publikováno v: Diabetes, Obesity & Metabolism

Aims To evaluate the injection success and user perception of a shield‐triggered pen‐injector mechanism. Methods The trial (http://ClinicalTrials.gov NCT02627287) was an exploratory, two‐centre, one‐visit, open‐label, randomized controlled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1b3b775cf6c768304055b85d5ca315
https://doi.org/10.1111/dom.13203

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2216-PUB: More Precise Assessment of Flow-Mediated Dilation (FMD) by Measuring at Maximum Dilatory Peak Time (MDP) in Subjects With and Without Type 2 Diabetes (T2D)

Autor: Theresa Herbrand, Hans Veit Coester, Christian Heiss, Tim Heise, Malte Kelm, Roberto Sansone, J. Hans DeVries

Publikováno v: Diabetes. 68

FMD is widely used to quantify endothelial function. FMD is calculated from the artery’s baseline diameter and peak diameter during reactive hyperemia. To this day, many published FMD results are based on values assessed at predefined time points,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::abb4be6ffe49a70a48d252a1a3b6c2cc
https://doi.org/10.2337/db19-2216-pub

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Steady state is reached within 2-3 days of once-daily administration of degludec, a basal insulin with an ultralong duration of action

Autor: Hanne Haahr, Stefan Korsatko, Tim Heise, Sigrid Deller, Hans Veit Coester, Marcus Hompesch, Stine Segel, R. Kapur, Carsten Roepstorff, Leszek Nosek

Publikováno v: Journal of Diabetes. 8:132-138

Background Various factors influence the pharmacokinetic and pharmacodynamic properties of insulin analogs. The aim of the present study was to determine time to steady state of insulin degludec (IDeg), a basal insulin analog with an ultralong durati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e9d53599f06377dd6eadce84d95b6615
https://doi.org/10.1111/1753-0407.12266

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Glucose-Lowering Effect of Insulin Degludec is Independent of Subcutaneous Injection Region

Autor: Carsten Roepstorff, Henrik F. Thomsen, Roxana Sin, Hans-Veit Coester, Leszek Nosek, Hanne Haahr, Tim Heise

Publikováno v: Clinical Drug Investigation

Background and Objectives Patients with diabetes mellitus inject insulin in different regions of the body. This study investigated the pharmacokinetic and pharmacodynamic properties of insulin degludec (IDeg), a new-generation once-daily basal insuli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c99aa8620ed476e274116abb5ad7848
https://doi.org/10.1007/s40261-014-0218-x

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Insulin Injection Into Lipohypertrophic Tissue: Blunted and More Variable Insulin Absorption and Action and Impaired Postprandial Glucose Control

Autor: Susanne Famulla, Lars Kaltheuner, Lidia Hermanski, Annelie Fischer, Laurence J. Hirsch, Ulrike Hövelmann, Lutz Heinemann, Matthias Kaltheuner, Tim Heise, Hans Veit Coester

Publikováno v: Diabetes care. 39(9)

OBJECTIVE Lipohypertrophy (LHT) is common in insulin-treated patients but its exact impact on insulin absorption and action is unclear. RESEARCH DESIGN AND METHODS In this crossover study, 13 patients with type 1 diabetes received subcutaneous abdomi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6379c52d2f8e4d3cd1db654836447df2
https://pubmed.ncbi.nlm.nih.gov/27411698

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Insulin degludec/insulin aspart produces a dose-proportional glucose-lowering effect in subjects with type 1 diabetes mellitus

Autor: Hanne Haahr, Tim Heise, Hans-Veit Coester, Leszek Nosek, Oliver Klein, Anne Louise Svendsen

Publikováno v: Diabetes, obesitymetabolism. 17(7)

Aims To evaluate the pharmacodynamic dose–response relationship of insulin degludec/insulin aspart (IDegAsp), a novel, soluble co-formulation of the ultra-long-acting basal insulin, insulin degludec (IDeg), with the rapid-acting prandial insulin (I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::690dc78426097b9f56b80e82fedf8b3d
https://pubmed.ncbi.nlm.nih.gov/25772444

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Steady state is reached within 2-3 days of once-daily administration of degludec, a basal insulin with an ultralong duration of action

Autor: Tim, Heise, Stefan, Korsatko, Leszek, Nosek, Hans Veit, Coester, Sigrid, Deller, Carsten, Roepstorff, Stine, Segel, Rahul, Kapur, Hanne, Haahr, Marcus, Hompesch

Publikováno v: Journal of diabetes. 8(1)

Various factors influence the pharmacokinetic and pharmacodynamic properties of insulin analogs. The aim of the present study was to determine time to steady state of insulin degludec (IDeg), a basal insulin analog with an ultralong duration of actio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91a2ec393def9a5bc239bb67e8bd6ba3
https://pubmed.ncbi.nlm.nih.gov/25581159

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