Zobrazeno 1 - 10
of 552
pro vyhledávání: '"Hans V. Westerhoff"'
Autor:
Yanhua Liu, Hans V. Westerhoff
Publikováno v:
npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract In multicellular organisms cells compete for resources or growth factors. If any one cell type wins, the co-existence of diverse cell types disappears. Existing dynamic Flux Balance Analysis (dFBA) does not accommodate changes in cell densit
Externí odkaz:
https://doaj.org/article/59701cf8180642b9ae6a6787733729a9
Autor:
Robert N. Goldberg, Robert T. Giessmann, Peter J. Halling, Carsten Kettner, Hans V. Westerhoff
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 303-316 (2023)
The measurement of values of apparent equilibrium constants K′ for enzyme-catalyzed reactions involve a substantial number of critical details, neglect of which could lead to systematic errors. Here, interferences, impurities in the substances used
Externí odkaz:
https://doaj.org/article/75af9735f6d14157b688b01859e67ecf
Autor:
Zahid Hassan, Hans V. Westerhoff
Publikováno v:
Toxics, Vol 12, Iss 1, p 89 (2024)
At a great many locations worldwide, the safety of drinking water is not assured due to pollution with arsenic. Arsenic toxicity is a matter of both systems chemistry and systems biology: it is determined by complex and intertwined networks of chemic
Externí odkaz:
https://doaj.org/article/55de6d1d77b94242b94ccfb37c2f7795
Publikováno v:
Life, Vol 13, Iss 11, p 2120 (2023)
Movile Cave, situated in Romania close to the Black Sea, constitutes a distinct and challenging environment for life. Its partially submerged ecosystem depends on chemolithotrophic processes for its energetics, which are fed by a continuous hypogenic
Externí odkaz:
https://doaj.org/article/65b05ec235f342f5a5884024870b2471
Autor:
Yanfei Zhang, Hans V. Westerhoff
Publikováno v:
Entropy, Vol 25, Iss 7, p 993 (2023)
Confronted with thermodynamically adverse output processes, free-energy transducers may shift to lower gears, thereby reducing output per unit input. This option is well known for inanimate machines such as automobiles, but unappreciated in biology.
Externí odkaz:
https://doaj.org/article/7dd4d28a6d7e4de8b0475a04b72aecbc
Autor:
Hans V. Westerhoff
Publikováno v:
Mathematics, Vol 11, Iss 11, p 2473 (2023)
Dynamic variables in the non-equilibrium systems of life are determined by catalytic activities. These relate to the expression of the genome. The extent to which such a variable depends on the catalytic activity defined by a gene has become more and
Externí odkaz:
https://doaj.org/article/3241b46290a94f1c8ea99e76eddffd47
System-Level Scenarios for the Elucidation of T Cell-Mediated Germinal Center B Cell Differentiation
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Germinal center (GC) reactions are vital to the correct functioning of the adaptive immune system, through formation of high affinity, class switched antibodies. GCs are transient anatomical structures in secondary lymphoid organs where specific B ce
Externí odkaz:
https://doaj.org/article/ec4019ff2f594d659270a9da72bde4d8
Autor:
Abulikemu Abudukelimu, Matteo Barberis, Frank Redegeld, Nilgun Sahin, Raju P. Sharma, Hans V. Westerhoff
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
We here apply a control analysis and various types of stability analysis to an in silico model of innate immunity that addresses the management of inflammation by a therapeutic peptide. Motivation is the observation, both in silico and in experiments
Externí odkaz:
https://doaj.org/article/592a5aed4107452b86b8f381e2e162c7
Autor:
Ewelina Weglarz-Tomczak, Thierry D. G. A. Mondeel, Diewertje G. E. Piebes, Hans V. Westerhoff
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 490 (2021)
How cancer cells utilize nutrients to support their growth and proliferation in complex nutritional systems is still an open question. However, it is certainly determined by both genetics and an environmental-specific context. The interactions betwee
Externí odkaz:
https://doaj.org/article/08ae7178c7024677b37d5f14792237a5
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Many a disease associates with inflammation. Upon binding of antigen-antibody complexes to immunoglobulin-like receptors, mast cells release tumor necrosis factor-α and proteases, causing fibroblasts to release endogenous antigens that may be cross
Externí odkaz:
https://doaj.org/article/55bd7b199f614be684db67fb207d585f