Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Hans T. Beck"'
Isolation and Biochemical Characterization of a New Topoisomerase I Inhibitor from Ocotea leucoxylon
Autor:
Michael R. Mattern, Xiangyang Wang, David G. I. Kingston, Hans T. Beck, Sidney Michael Hecht, Bing-Nan Zhou, Randall K. Johnson, and Alonzo Ortiz
Publikováno v:
Journal of Natural Products. 63:217-221
In a continuation of our search for potential tumor inhibitors from plants, we found that a crude extract from Ocotea leucoxylon showed selective activity typical of inhibitors of the enzyme topoisomerase I in a yeast assay for DNA-damaging agents. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53bd7f5a2d8bab0c91ce2a94a0a9c7dd
https://doi.org/10.1021/np990442s
https://doi.org/10.1021/np990442s
Autor:
S. N. Tiwari, John G. Menke, Sheo B. Singh, Jeremy Moss, Ziqiang Guan, Neelam Sharma, Hans T. Beck, Nelson Zamora, Marvin J Schulman, John G. Ondeyka, Aisha Ali, Robert P. Borris, Nancy S. Hayes, Wil de Jong, Hiranthi Jayasuriya, Kithsiri Herath, Marc Slattery, Dennis W Stevenson, Flor Chavez, Karen L. MacNaul
Publikováno v:
Journal of natural products. 68(8)
It has been demonstrated that liver X receptors (LXR) play a significant role in cholesterol homeostasis. Agonists of LXR are expected to increase cellular cholesterol efflux, lower LDL, and raise HDL levels. Screening of a natural product library of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17005f1f2c635939f8623c59f8c173f8
https://pubmed.ncbi.nlm.nih.gov/16124770
https://pubmed.ncbi.nlm.nih.gov/16124770
Autor:
Mervyn C, Lötter, Hans T, Beck
Publikováno v:
BMC Ecology, Vol 4, Iss 1, p 9 (2004)
BMC Ecology
BMC Ecology
Background Mixed evergreen forests form the smallest, most widely distributed and fragmented biome in southern Africa. Within South Africa, 44% of this vegetation type has been transformed. Afromontane forest only covers 0.56 % of South Africa, yet i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::16d452edc55f4e1cb18aa0c71d29e9f1
http://www.biomedcentral.com/1472-6785/4/9
http://www.biomedcentral.com/1472-6785/4/9
Autor:
Hiranthi Jayasuriya, Lynn Gregory, Sheo B. Singh, Michael J. Balick, Deborah L. Zink, Weerachai Nanakorn, Wesley L Shoop, Robert P. Borris, Michael A. Goetz, Hans T. Beck
Publikováno v:
Journal of natural products. 67(2)
Four new congeners, rediocides B-E (2-5), of the previously reported rediocide A (1) were isolated from a methanol extract of the roots of the plant Trigonostemon reidioides. The structures of these minor analogues were elucidated by comparison of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6533ab4b4c78f10ede417d2226ad4db8
https://pubmed.ncbi.nlm.nih.gov/14987064
https://pubmed.ncbi.nlm.nih.gov/14987064
Autor:
Alex Elbrecht, Otto D. Hensens, Hans T. Beck, Robert P. Borris, Michael J. Balick, D. L. Zink, Yuli Chen, Tannis M. Jurgens
Publikováno v:
Insect biochemistry and molecular biology. 26(6)
We have identified a novel nonsteroidal ecdysteroid agonist. This compound was isolated from a methanol extract of Ajuga reptans L. (Lamiaceae) and the structure was identified by spectroscopic methods as 8- O -acetylharpagide. We have characterised
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8a59b400175e206ba22163f65a0272f
https://pubmed.ncbi.nlm.nih.gov/8969463
https://pubmed.ncbi.nlm.nih.gov/8969463
Autor:
Jon D. Polishook, Russell B. Lingham, Claude Dufresne, Lin Kong, Gregory E. Koch, Isabel Martin, John G. Ondeyka, Jerrold M. Liesch, Tannis M. Jurgens, Ermenegilda McCauley, Hans T. Beck, Robert P. Borris, Carmen Cascales, Steven R. King, Otto D. Hensens, Susan L. Raghoobar, Fernando Pelaez, Michael J. Salvatore, Suzanne E. Gartner, Deborah L. Zink, Maria Teresa Diez, Michael J. Balick, Amy Hsu
Publikováno v:
Journal of natural products. 57(6)
gamma-Pyrone-3-acetic acid (L-741,494) is a novel metabolite produced by a culture of the fungal genus Xylaria. This substance is a water-soluble, competitive, irreversible inhibitor of Interleukin-1 beta Converting Enzyme that is inactive against pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45e9a2ee1fd30271b159348c420e883a
https://pubmed.ncbi.nlm.nih.gov/7931364
https://pubmed.ncbi.nlm.nih.gov/7931364
Autor:
Deborah L. Zink, Easter G. Frazier, Michael J. Balick, Hans T. Beck, James M. Schaeffer, Tracey E. Jones, Tannis M. Jurgens, Robert P. Borris, Weerachai Nanakorn
Publikováno v:
Journal of natural products. 57(2)
Curcuma comosa is a member of the economically important plant family, Zingiberaceae. A methanolic extract of C. comosa was shown to be nematocidal when tested against the free-living nematode Caenorhabditis elegans. Five diphenylheptanoids [1-5], on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3cff168204057e526a092dcd8b22d32
https://pubmed.ncbi.nlm.nih.gov/8176399
https://pubmed.ncbi.nlm.nih.gov/8176399
Autor:
Robert P. Borris, Michael A. Goetz, Deborah L. Zink, † Michelle Zakson-Aiken, Suresh B. Singh, Michael J. Balick, Hiranthi Jayasuriya, Lyndia Slayton, Lynn Gregory, and Wesley Shoop, Weerachai Nanakorn, Sheo B. Singh, Hans T. Beck
Publikováno v:
Journal of the American Chemical Society. 122:4998-4999
Highly Modified Daphnane from Trigonostemon reidioides Exhibiting Potent Insecticidal Activity Hiranthi Jayasuriya,† Deborah L. Zink,† Suresh B. Singh,† Robert P. Borris,† Weerachai Nanakorn,‡ Hans T. Beck, Michael J. Balick, Michael A. Goe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53654f3a8c8d547e59b788a5ec6616c1
https://doi.org/10.1021/ja994074q
https://doi.org/10.1021/ja994074q
Autor:
Hans T Beck, Mervyn C Lötter
Publikováno v:
BMC Ecology. 4:9
Background Mixed evergreen forests form the smallest, most widely distributed and fragmented biome in southern Africa. Within South Africa, 44% of this vegetation type has been transformed. Afromontane forest only covers 0.56 % of South Africa, yet i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca2699d78eb99498876e14ee9352fb39
https://doi.org/10.1186/1472-6785-4-9
https://doi.org/10.1186/1472-6785-4-9
Autor:
Hans T. Beck
Publikováno v:
Brittonia. 44:306
Paullinia lachnocarpa has been known only from flowering and immature fruiting material collected in Ecuador. A recent collection with mature fruit shows that this biternate-leaved plant with multi-stelar stems and schizocarpic (indehiscent) fruit is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e61c3897754e306db2977f03940f5bfd
https://doi.org/10.2307/2806929
https://doi.org/10.2307/2806929