Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Hans Senn"'
Autor:
Christian Czech, Peter Berndt, Kristina Busch, Oliver Schmitz, Jan Wiemer, Veronique Most, Harald Hampel, Jürgen Kastler, Hans Senn
Publikováno v:
PLoS ONE, Vol 7, Iss 2, p e31501 (2012)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive loss of cognitive functions. Today the diagnosis of AD relies on clinical evaluations and is only late in the disease. Biomarkers for early detection of the underly
Externí odkaz:
https://doaj.org/article/5d6acbd08c054654ab0d79588cca5d30
Publikováno v:
CHIMIA, Vol 61, Iss 10 (2007)
Externí odkaz:
https://doaj.org/article/9020971bf4084d13887c34c1c1690ea7
Double glass transitions in single-component homogeneous liquids due to intramolecular vitrification
Autor:
Ben Russell, Mario González-Jiménez, Nikita Tukachev, Laure-Anne Hayes, Tajrian Chowdhury, Uroš Javornik, Gregor Mali, Manlio Tassieri, Joy Farnaby, Hans Senn, Klaas Wynne
On supercooling a liquid, the viscosity rises rapidly until at the glass transition it vitrifies into an amorphous solid accompanied by a steep drop in the heat capacity. Therefore, a pure homogeneous liquid is not expected to display more than one g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b845f226a750d77cf3162e1cef78ee
https://doi.org/10.26434/chemrxiv-2022-zrbgt-v3
https://doi.org/10.26434/chemrxiv-2022-zrbgt-v3
Autor:
Ben Russell, Nikita Tukachev, Mario González-Jiménez, Laure-Anne Hayes, Tajrian Chowdhury, Uroš Javornik, Gregor Mali, Joy Farnaby, Manlio Tassieri, Hans Senn, Klaas Wynne
At the glass transition, a supercooled liquid vitrifies into an amorphous solid and all viscous relaxation processes cease. The experimental observation of secondary or β relaxations below the glass transition temperature in molecular and metallic g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6231a4d7b376f9c893e8e1a53ccfc04b
https://doi.org/10.26434/chemrxiv-2022-zrbgt
https://doi.org/10.26434/chemrxiv-2022-zrbgt
Autor:
Alexander, Amberg, Björn, Riefke, Götz, Schlotterbeck, Alfred, Ross, Hans, Senn, Frank, Dieterle, Matthias, Keck
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1641
Metabolomics, also often referred as "metabolic profiling," is the systematic profiling of metabolites in biofluids or tissues of organisms and their temporal changes. In the last decade, metabolomics has become more and more popular in drug developm
Autor:
Alexander Amberg, Björn Riefke, Götz Schlotterbeck, Alfred Ross, Hans Senn, Frank Dieterle, Matthias Keck
Publikováno v:
Methods in Molecular Biology ISBN: 9781493971701
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f41c0c89001c8eb0bf9e8c80d21f9164
https://doi.org/10.1007/978-1-4939-7172-5_13
https://doi.org/10.1007/978-1-4939-7172-5_13
Autor:
Mark Symes, Giacomo Cioncoloni, Isolda Roger, Claire Wilson, Hans Senn, Paul Wheatley, Stephen Sproules, Russell Morris
Publikováno v:
ECS Meeting Abstracts. :2089-2089
The selective and efficient electrocatalytic reduction of nitrite to nitric oxide (NO) is of tremendous importance, both for the development of NO-release systems for biomedical applications and for the removal of nitrogen oxide pollutants from the e
Autor:
Hans Senn, Laura Suter, Thomas Singer, Holger Fischer, Miklos Csato, Stefan Evers, Lucette Doessegger, Georg Schmitt, Elke-Astrid Atzpodien, Götz Schlotterbeck, Barbara Lenz
Publikováno v:
Therapeutic Advances in Drug Safety. 4:101-114
Background: Phospholipidosis (PLD) is a lysosomal storage disorder induced by a class of cationic amphiphilic drugs. However, drug-induced PLD is reversible. Evidence of PLD from animal studies with some compounds has led to discontinuation of develo
Publikováno v:
Pharmacogenomics. 7:1055-1075
The state-of-the-art of nuclear magnetic resonance spectroscopy, mass spectrometry and statistical tools for the acquisition and evaluation of complex multidimensional spectroscopic data in metabolic profiling is reviewed in this article. The continu
Publikováno v:
Chemical Research in Toxicology. 19:1175-1181
Selecting drug candidates based on toxicity is an important step in early drug development. In this case study, it is shown how metabonomics is applied to a ranking study, in which drug candidates with equal pharmacological activities are selected ba