Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Hans Rorsman"'
Publikováno v:
Acta Pathologica Microbiologica Scandinavica. 69:179-184
Publikováno v:
Journal of Neurochemistry. 62:2030-2036
Model melanins, synthesized with different cysteinyldopamine/dopamine ratios in the incubates, were oxidized with KMnO4 and the resulting compounds were analyzed by HPLC. The ratios between a phaeomelanin-derived compound, thiazole-4,5-dicarboxylic a
Autor:
Evald Rosengren, Christine N. Metz, Lars Jacobsson, Hans Rorsman, Richard Bucala, Gerd Odh, Pierre Åman
Publikováno v:
Europe PubMed Central
BACKGROUND: Recent studies of melanin biosynthesis have uncovered an unusual enzymatic activity which converts the non-naturally occurring D-isomer of 2-carboxy-2,3-dihydroindole-5,6-quinone (dopachrome) into 5,6-dihydroxyindole-2-carboxylic acid (DH
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1268:300-310
Melanin synthesis in the mouse involves the interaction of many pigmentation loci. Tyrosinase, the product of the albino (c) locus, catalyses the first step of the pathway. The brown (b) locus protein has significant homology to tyrosinase and contro
Publikováno v:
Pigment Cell Research. 7:305-310
The mouse b locus controls black/brown coat coloration. Its product, the b-protein or TRP-1, has significant homology to tyrosinase, and this has led to suggestions that the b-protein is itself a melanogenic enzyme. In order to investigate its functi
Publikováno v:
Journal of Investigative Dermatology. 100:S209-S213
The effects of systems generating active oxygen species (su-peroxide anion, hydrogen peroxide, hydroxyl radical) on tyrosinase have been studied in cultured human melanoma cells. Tyrosinase activity was determined by measuring the quantity of 5-S-L-c
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1097:152-160
The pigment of the human substantia nigra was isolated after extraction of lipids and proteins with 2% sodium cholate in 30% ethanol followed by 2% sodium dodecyl sulfate in 10% glycerol. The pigment was hydrolysed with HI or degraded by treatment wi
Publikováno v:
Pigment Cell Research. 3:11-15
The effects of N-acetyl-L-cysteine (L-NAC), N,N-diacetyl-L-cystine (oxidized form of L-NAC) and N-acetyl-D-cysteine on the intracellular glutathione (GSH) level and their toxicity were investigated in the human melanoma cell culture IGR1. L-NAC appli
Autor:
Hans Rorsman
Publikováno v:
Pigment Cell Research; 17(2), pp 191-202 (2004)
As a redhead I have had a personal interest in red hair, freckles and sunburns since childhood. An observation of a formaldehyde-induced fluorescence in human epidermal melanocytes initiated my scientific interest in these cells. Prota and Nicolaus d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba7a819b498ed9aa5711f81f2d4b0e9
https://lup.lub.lu.se/record/121331
https://lup.lub.lu.se/record/121331
Autor:
Hans Rorsman, Jürgen Bernhagen, Evald Rosengren, Nguyen Tuyet Mai, Ralf Mischke, Robert Kleemann
Publikováno v:
European journal of biochemistry. 267(24)
Macrophage migration inhibitory factor (MIF) is a cytokine with broad regulatory functions in innate immunity. MIF belongs to the few cytokines displaying catalytic activities, i.e. MIF has a Pro2-dependent tautomerase and a Cys-Ala-Leu-Cys (CALC) cy