Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Hans Reiser"'
Autor:
Seraina Cooksley-Decasper, Hans Reiser, Daniela S Thommen, Barbara Biedermann, Michel Neidhart, Joanna Gawinecka, Gieri Cathomas, Fabian C Franzeck, Christophe Wyss, Roland Klingenberg, Paolo Nanni, Bernd Roschitzki, Christian Matter, Petra Wolint, Maximilian Y Emmert, Marc Husmann, Beatrice Amann-Vesti, Wilibald Maier, Steffen Gay, Thomas F Lüscher, Arnold von Eckardstein, Danielle Hof
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47985 (2012)
To date, no plaque-derived blood biomarker is available to allow diagnosis, prognosis or monitoring of atherosclerotic vascular diseases. In this study, specimens of thrombendarterectomy material from carotid and iliac arteries were incubated in prot
Externí odkaz:
https://doaj.org/article/bb51be72e980485c9302e17808f891b8
Autor:
William Plunkett, Hans Reiser, Michael J. Keating, Daniel B. Tumas, Adrian S. Ray, Cheng-Yu Tsai
Supplementary Data from Targeting DNA Repair in Chronic Lymphocytic Leukemia Cells with a Novel Acyclic Nucleotide Analogue, GS-9219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46e8726742734015537fc20eb4fe0a70
https://doi.org/10.1158/1078-0432.22439287.v1
https://doi.org/10.1158/1078-0432.22439287.v1
Autor:
William Plunkett, Hans Reiser, Michael J. Keating, Daniel B. Tumas, Adrian S. Ray, Cheng-Yu Tsai
Purpose: GS-9219 is a cell-permeable prodrug of the acyclic nucleotide analogue 9-(2-phosphonylmethoxyethyl)guanine (PMEG); the incorporation of the active metabolite PMEG diphosphate (PMEGpp) into DNA results in DNA chain termination due to the lack
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001a3bce799d9b04e4388e5e5ecef070
https://doi.org/10.1158/1078-0432.c.6516781
https://doi.org/10.1158/1078-0432.c.6516781
Autor:
Jörg Petersen, Eckart Schott, G Felten, Thomas Berg, T. Warger, Karl-Georg Simon, Markus Cornberg, Julian Schulze-Zur-Wiesch, Christoph Eisenbach, Stefan Mauss, Tania M. Welzel, Hans Reiser, Finite Chb study investigators, Marjoleine L. Op den Brouw, Lothar Gallo, Belinda Jump, Reinhart Zachoval, Dietmar M. Klass, Renate Heyne
Publikováno v:
Journal of Hepatology. 67:918-924
Background & Aims There is currently no virological cure for chronic hepatitis B but successful nucleos(t)ide analogue (NA) therapy can suppress hepatitis B virus (HBV) DNA replication and, in some cases, result in HBsAg loss. Stopping NA therapy oft
Autor:
Douglas H. Thamm, Michael J. Hawkins, Darius Babusis, Christie Anderson, David M. Vail, William J. Watkins, Hans Reiser, Grushenka H.I. Wolfgang, Jessica Lawrence, Robert Jeraj, M Vanderhoek, Mackenzie A. Wessel, Ilana N. Henne, Ilene D. Kurzman, Adrian S. Ray, Daniel B. Tumas, Cecilia S. Robat, Susan Plaza
Publikováno v:
Clinical Cancer Research. 15:3503-3510
Purpose: To assess, in dogs with naturally occurring non-Hodgkin's lymphoma, pharmacokinetics, safety, and activity of GS-9219, a prodrug of the nucleotide analogue 9-(2-phosphonylmethoxyethyl) guanine (PMEG), which delivers PMEG and its phosphorylat
Autor:
David A. Oare, I-hung Shih, Laura S. Lehman, Erik De Clercq, Eric Mabery, Steven S. Bondy, Weidong Zhong, Inge Vliegen, Matthew Paulson, Johan Neyts, Gerhard Pürstinger, Hans Reiser, Jan Paeshuyse, Nina Boddeker, Tine De Burghgraeve, William A. Lee
Publikováno v:
Journal of Hepatology
Background/Aims Following lead optimization, a set of substituted imidazopyridines was identified as potent and selective inhibitors of in vitro HCV replication. The particular characteristics of one of the most potent compounds in this series (5-[[3
Autor:
Nicolas Rodondi, Peter Vollenweider, Helena Marti Soler, Danielle Hof, Alexander Akhmedov, Dik Heg, Arnold von Eckardstein, Pedro Marques-Vidal, Ulf Landmesser, Thomas F. Lüscher, Stefan Zoller, Joanna Gawinecka, Stephan Windecker, Roland Klingenberg, Nina Fuchs, François Mach, Seraina Cooksley-Decasper, Christian M. Matter, Hans Reiser
Publikováno v:
Reiser, Hans; Klingenberg, Roland; Hof, Danielle; Cooksley-Decasper, Seraina; Fuchs, Nina; Akhmedov, Alexander; Zoller, Stefan; Marques-Vidal, Pedro; Marti Soler, Helena; Heg, Dik; Landmesser, Ulf; Rodondi, Nicolas; Mach, Francois; Windecker, Stephan; Vollenweider, Peter; Matter, Christian M; Lüscher, Thomas F; von Eckardstein, Arnold; Gawinecka, Joanna (2015). Circulating FABP4 Is a Prognostic Biomarker in Patients With Acute Coronary Syndrome but Not in Asymptomatic Individuals. Arteriosclerosis, thrombosis, and vascular biology, 35(8), pp. 1872-1879. Lippincott Williams & Wilkins 10.1161/ATVBAHA.115.305365
Arteriosclerosis thrombosis and vascular biology
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Arteriosclerosis thrombosis and vascular biology
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
Objective— Blood-borne biomarkers reflecting atherosclerotic plaque burden have great potential to improve clinical management of atherosclerotic coronary artery disease and acute coronary syndrome (ACS). Approach and Results— Using data integrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07406fb39c09d20f088c03869ab1ceaa
https://doi.org/10.5167/uzh-111377
https://doi.org/10.5167/uzh-111377
Autor:
Jesús González-Cabrero, Arlene H. Sharpe, Catherine J. Wise, Hans Reiser, Gordon J. Freeman, Yvette Latchman
Publikováno v:
Proceedings of the National Academy of Sciences. 96:1019-1023
We have generated mice deficient in the expression of the lymphocyte cell surface antigen CD48 (Blast-1, BCM1, sgp-60) by gene targeting in embryonic stem cells. Mice homozygous for the CD48 mutation (CD48−/−mice) are severely impaired in CD4+T c
Autor:
Hans Reiser, Yvette Latchman
Publikováno v:
European Journal of Immunology. 28:4325-4331
The physiological functions of murine CD2 and its ligand CD48 are uncertain. We have examined the role of the CD2-CD48 interaction in murine T cell activation using a series of Chinese hamster ovary (CHO) cell transfectants. CHO cells expressing I-Ad
Publikováno v:
The Journal of Immunology. 161:5809-5812
The CD48 molecule belongs to a subfamily of the Ig superfamily that also includes the CD2, CD58, 2B4, Signaling lymphocyte activation molecule (SLAM), and Ly-9 molecules. Receptor-ligand interactions are known to occur between several members of this