Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Hans Raskov"'
Autor:
Lasse Kvich, Blaine Gabriel Fritz, Henrike Zschach, Thilde Terkelsen, Hans Raskov, Kathrine Høst-Rasmussen, Morten Ragn Jakobsen, Alexandra Gabriella Gheorghe, Ismail Gögenur, Thomas Bjarnsholt
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTExtensive research has explored the role of gut microbiota in colorectal cancer (CRC). Nonetheless, metatranscriptomic studies investigating the in situ functional implications of host-microbe interactions in CRC are scarce. Therefore, we cha
Externí odkaz:
https://doaj.org/article/12d099f554524bf1961caa72ca922e22
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34361- (2024)
In cancer, activation of platelets by tumor cells is critical to disease progression. Development of precise antiplatelet targeting may improve outcomes from anticancer therapy.Alongside a distinct shift in functionality such as pro-metastatic and pr
Externí odkaz:
https://doaj.org/article/b684712a944e4fb185f3220737eabd60
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 43, Iss , Pp 100923- (2023)
Background: Evidence suggests that the human gut microbiota modulates the treatment response of immune checkpoint inhibitors (ICI) in cancer. Thus, finding predictive biomarkers in the fecal gut microbiota of patients who are less likely to respond t
Externí odkaz:
https://doaj.org/article/752672dd91f242f183a2d9e5f3a2dc5e
Autor:
Susanne Brix, Ismail Gögenur, Mustafa Bulut, Lasse Bremholm Hansen, Mikail Gögenur, Lukas Balsevicius, Nesibe Colak, Tobias Freyberg Justesen, Anne-Marie Kanstrup Fiehn, Marianne Bøgevang Jensen, Kathrine Høst-Rasmussen, Britt Cappelen, Shruti Gaggar, Asma Tajik, Jawad Ahmad Zahid, Astrid Louise Bjørn Bennedsen, Tommaso Del Buono D’Ondes, Hans Raskov, Susanne Gjørup Sækmose, Ali Salanti
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background In colorectal cancer, the effects of immune checkpoint inhibitors are mostly limited to patients with deficient mismatch repair tumors, characterized by a high grade infiltration of CD8+T cells. Interventions aimed at increasing intratumor
Externí odkaz:
https://doaj.org/article/94c6d0a449c0483fae25a919b3acb501
Publikováno v:
Oncogenesis, Vol 11, Iss 1, Pp 1-16 (2022)
Abstract Neutrophils are central mediators of innate and adaptive immunity and first responders to tissue damage. Although vital to our health, their activation, function, and resolution are critical to preventing chronic inflammation that may contri
Externí odkaz:
https://doaj.org/article/7eaa2f78c92445f3bac313b5e7e77672
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Our understanding of the tumor microenvironment (TME), including the interplay between tumor cells, stromal cells, immune cells, and extracellular matrix components, is mandatory for the innovation of new therapeutic approaches in cancer. The cell-ce
Externí odkaz:
https://doaj.org/article/40dcc8a4cb1b4a96b0ec8b91f459a3e8
Publikováno v:
Clinical and Translational Medicine, Vol 7, Iss 1, Pp 1-4 (2018)
Abstract Background Research in the field of relation between microbes and colorectal carcinogenesis has gained increasing interest in past years. Recently, link between microbial biofilm and carcinogenesis in colon was demonstrated by several author
Externí odkaz:
https://doaj.org/article/318a1b21c0074524843d3688a19abf47
Publikováno v:
Raskov, H, Gaggar, S, Tajik, A, Orhan, A & Gögenur, I 2023, ' The Matrix Reloaded—The Role of the Extracellular Matrix in Cancer ', Cancers, vol. 15, no. 7, 2057 . https://doi.org/10.3390/cancers15072057
As the core component of all organs, the extracellular matrix (ECM) is an interlocking macromolecular meshwork of proteins, glycoproteins, and proteoglycans that provides mechanical support to cells and tissues. In cancer, the ECM can be remodelled i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e7bf816227009023531759369ea866a
https://curis.ku.dk/ws/files/345118782/The_Matrix_Reloaded.pdf
https://curis.ku.dk/ws/files/345118782/The_Matrix_Reloaded.pdf
Publikováno v:
Raskov, H, Gaggar, S, Tajik, A, Orhan, A & Gögenur, I 2023, ' Metabolic switch in cancer – Survival of the fittest ', European Journal of Cancer, vol. 180, pp. 30-51 . https://doi.org/10.1016/j.ejca.2022.11.025
Cell metabolism is characterised by the highly coordinated conversion of nutrients into energy and biomass. In solid cancers, hypoxia, nutrient deficiencies, and tumour vasculature are incompatible with accelerated anabolic growth and require a rewir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ee2a32d390ab2fe17f31707a55280b8
https://curis.ku.dk/portal/da/publications/metabolic-switch-in-cancer--survival-of-the-fittest(ca442500-a65e-4c85-bca8-b0b426521cf8).html
https://curis.ku.dk/portal/da/publications/metabolic-switch-in-cancer--survival-of-the-fittest(ca442500-a65e-4c85-bca8-b0b426521cf8).html
Autor:
Mikail Gögenur, Lukas Balsevicius, Mustafa Bulut, Nesibe Colak, Tobias Freyberg Justesen, Anne-Marie Kanstrup Fiehn, Marianne Bøgevang Jensen, Kathrine Høst-Rasmussen, Britt Cappelen, Shruti Gaggar, Asma Tajik, Jawad Ahmad Zahid, Astrid Louise Bjørn Bennedsen, Tommaso Del Buono D’Ondes, Hans Raskov, Susanne Gjørup Sækmose, Lasse Bremholm Hansen, Ali Salanti, Susanne Brix, Ismail Gögenur
Publikováno v:
Gögenur, M, Balsevicius, L, Bulut, M, Colak, N, Justesen, T F, Fiehn, A-M K, Jensen, M B, Høst-Rasmussen, K, Cappelen, B, Gaggar, S, Tajik, A, Zahid, J A, Bennedsen, A L B, D'Ondes, T D B, Raskov, H, Sækmose, S G, Hansen, L B, Salanti, A, Brix, S & Gögenur, I 2023, ' Neoadjuvant intratumoral influenza vaccine treatment in patients with proficient mismatch repair colorectal cancer leads to increased tumor infiltration of CD8+ T cells and upregulation of PD-L1: a phase 1/2 clinical trial ', Journal for ImmunoTherapy of Cancer, vol. 11, no. 5, e006774 . https://doi.org/10.1136/jitc-2023-006774
BackgroundIn colorectal cancer, the effects of immune checkpoint inhibitors are mostly limited to patients with deficient mismatch repair tumors, characterized by a high grade infiltration of CD8+T cells. Interventions aimed at increasing intratumora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f85e690fee350b864f70c666637cc7
https://orbit.dtu.dk/en/publications/53ac1b78-d29d-4cff-95bd-e42a69c92f71
https://orbit.dtu.dk/en/publications/53ac1b78-d29d-4cff-95bd-e42a69c92f71