Zobrazeno 1 - 1
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pro vyhledávání: '"Hans Ragnar Widlund"'
Autor:
Belinda Wang, Elsa Beyer Krall, Andrew James Aguirre, Miju Kim, Hans Ragnar Widlund, Mihir Bhavik Doshi, Ewa Sicinska, Rita Sulahian, Amy Goodale, Glenn Spencer Cowley, Federica Piccioni, John Gerard Doench, David Edward Root, William Chun Hahn
Publikováno v:
Cell Reports, Vol 18, Iss 6, Pp 1543-1557 (2017)
Intrinsic resistance and RTK-RAS-MAPK pathway reactivation has limited the effectiveness of MEK and RAF inhibitors (MAPKi) in RAS- and RAF-mutant cancers. To identify genes that modulate sensitivity to MAPKi, we performed genome-scale CRISPR-Cas9 los
Externí odkaz:
https://doaj.org/article/be8a210ebb1a489e99d35a897dbf44e3
