Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Hans Peter Wendel"'
Autor:
Josefin Weber, Carsten Linti, Christiane Lörch, Marbod Weber, Madelene Andt, Christian Schlensak, Hans Peter Wendel, Michael Doser, Meltem Avci-Adali
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract The liver is a vital organ with numerous functions, including metabolic functions, detoxification, and the synthesis of secretory proteins. The increasing prevalence of liver diseases requires the development of effective treatments, models,
Externí odkaz:
https://doaj.org/article/8ce0e14443554919a9f0af2306140695
Autor:
Sonia Golombek, Thomas Hoffmann, Ludmilla Hann, Markus Mandler, Sabine Schmidhuber, Josefin Weber, Young-Tae Chang, Roman Mehling, Andrea Ladinig, Christian Knecht, Johanna Leyens, Christian Schlensak, Hans Peter Wendel, Achim Schneeberger, Meltem Avci-Adali
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 642-654 (2023)
Loss of elastin due to aging, disease, or injury can lead to impaired tissue function. In this study, de novo tropoelastin (TE) synthesis is investigated in vitro and in vivo using different TE-encoding synthetic mRNA variants after codon optimizatio
Externí odkaz:
https://doaj.org/article/fb35e12ee64a40e1bef0ae30f9a604f7
Autor:
Tiago Granja, Harry Magunia, Patricia Schüssel, Claudius Fischer, Thomas Prüfer, David Schibilsky, Lina Serna-Higuita, Hans Peter Wendel, Christian Schlensak, Helene Häberle, Peter Rosenberger, Andreas Straub
Publikováno v:
Platelets, Vol 33, Iss 1, Pp 132-140 (2022)
Blood flow through left ventricular assist devices (LVAD) may induce activation and dysfunction of platelets. Dysfunctional platelets cause coagulation disturbances and form platelet-neutrophil conjugates (PNC), which contribute to inflammatory tissu
Externí odkaz:
https://doaj.org/article/224193a79db94d35ab1add160e7ab36f
Autor:
Yan Xu, Yichen Xu, Wentai Zhang, Ming Li, Hans-Peter Wendel, Jürgen Geis-Gerstorfer, Ping Li, Guojiang Wan, Shulan Xu, Tao Hu
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Zinc-based nanoparticles, nanoscale metal frameworks and metals have been considered as biocompatible materials for bone tissue engineering. Among them, zinc-based metals are recognized as promising biodegradable materials thanks to their moderate de
Externí odkaz:
https://doaj.org/article/e301321faddf4269828f139c8a8ec136
Autor:
David Schibilsky, Setsuo Takatani, Barbara Schibilsky, Tobias Graf, Diana Michels da Silva, Hans Peter Wendel, Meltem Avci-Adali, Christian Schlensak
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract The specific hemocompatibility properties of mechanical-circulatory-support (MCS)-pump technologies have not previously been described in a comparable manner. We thus investigated the hemocompatibility-indicating marker of a new magnetically
Externí odkaz:
https://doaj.org/article/3c09ace527474b75b80c2b7b34381cb0
Publikováno v:
Bioengineering, Vol 10, Iss 4, p 411 (2023)
Polytetrafluoroethylene (PTFE) is a commonly used biomaterial for the manufacturing of vascular grafts and several strategies, such as coatings, have been explored to improve the hemocompatibility of small-diameter prostheses. In this study, the hemo
Externí odkaz:
https://doaj.org/article/5b4801f544da40a685f7d294bbb66659
Autor:
Heidrun Steinle, Marbod Weber, Andreas Behring, Ulrike Mau-Holzmann, Christiane von Ohle, Aron-Frederik Popov, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 17, Iss , Pp 907-921 (2019)
The generation of induced pluripotent stem cells (iPSCs) from patient’s somatic cells and the subsequent differentiation into desired cell types opens up numerous possibilities in regenerative medicine and tissue engineering. Adult cardiomyocytes h
Externí odkaz:
https://doaj.org/article/fff8a0397eab4e55a6f4326f58019092
Autor:
Tatjana Michel, Sonia Golombek, Heidrun Steinle, Ludmilla Hann, Ana Velic, Boris Macek, Stefanie Krajewski, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali
Publikováno v:
Journal of Biological Engineering, Vol 13, Iss 1, Pp 1-11 (2019)
Abstract The application of synthetic modified messenger RNA (mRNA) is a promising approach for the treatment of a variety of diseases and vaccination. In the past few years, different modifications of synthetic mRNA were applied to render the mRNA m
Externí odkaz:
https://doaj.org/article/f2ac91389bdb445bbf44ad8f54392b17
Autor:
Denis Canjuga, Heidrun Steinle, Jana Mayer, Ann-Kristin Uhde, Gerd Klein, Hans Peter Wendel, Christian Schlensak, Meltem Avci-Adali
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1194 (2022)
Endothelial progenitor cells (EPCs) are one of the most important stem cells for the neovascularization of tissues damaged by ischemic diseases such as myocardial infarction, ischemic stroke, or critical limb ischemia. However, their low homing effic
Externí odkaz:
https://doaj.org/article/4b439f7ec8e94e89bc4086d8250378f5
Autor:
Lusine Danielyan, Matthias Schwab, Georg Siegel, Bianca Brawek, Olga Garaschuk, Nithi Asavapanumas, Marine Buadze, Ali Lourhmati, Hans-Peter Wendel, Meltem Avci-Adali, Marcel A. Krueger, Carsten Calaminus, Ulrike Naumann, Stefan Winter, Elke Schaeffeler, Annett Spogis, Sandra Beer-Hammer, Jonas J. Neher, Gabriele Spohn, Anja Kretschmer, Eva-Maria Krämer-Albers, Kerstin Barth, Hong Jun Lee, Seung U. Kim, William H. Frey, II, Claus D. Claussen, Dirk M. Hermann, Thorsten R. Doeppner, Erhard Seifried, Christoph H. Gleiter, Hinnak Northoff, Richard Schäfer
Publikováno v:
EBioMedicine, Vol 60, Iss , Pp 102989- (2020)
Background: Stem cells` (SC) functional heterogeneity and its poorly understood aetiology impedes clinical development of cell-based therapies in regenerative medicine and oncology. Recent studies suggest a strong correlation between the SC migration
Externí odkaz:
https://doaj.org/article/50fadaeaeb26482dbe9ab2d00b7b2fef